Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner

Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress

(2018) Susan J. Gelman et al.   Cell Reports

Systematic Identification of Oncogenic EGFR Interaction Partners

(2017) Julia Petschnigg et al.   JOURNAL OF MOLECULAR BIOLOGY

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells

(2017) A L Schroyer et al.   ONCOGENE

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells

(2017) Lorenzo Bazzani et al.   Oncotarget

Quantification of lactate from various metabolic pathways and quantification issues of lactate isotopologues and isotopmers

(2017) Wei Zhang et al.   Scientific Reports

Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT)

(2016) Mi Lai et al.   MOLECULAR & CELLULAR PROTEOMICS

Transketolase counteracts oxidative stress to drive cancer development

(2016) Iris Ming-Jing Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A key role for transketolase-like 1 in tumor metabolic reprogramming

(2016) Santiago Diaz-Moralli et al.   Oncotarget

Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?

(2015) Maria Peiris-Pagès et al.   Cell Metabolism

The Long Intergenic Noncoding RNA UFC1, a Target of MicroRNA 34a, Interacts With the mRNA Stabilizing Protein HuR to Increase Levels of β-Catenin in HCC Cells

(2015) Chuanhui Cao et al.   GASTROENTEROLOGY

A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity

(2015) Richard M. Monaghan et al.   NATURE CELL BIOLOGY

Standardizing chromatin research: a simple and universal method for ChIP-seq

(2015) Laura Arrigoni et al.   NUCLEIC ACIDS RESEARCH

Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival

(2015) D Dayde et al.   ONCOGENE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

EGFR and NF-κB: partners in cancer

(2015) Kateryna Shostak et al.   TRENDS IN MOLECULAR MEDICINE

Surgical Treatment for Hepatocellular Carcinoma

(2015) MazenM Hassanain et al.   Saudi Journal of Gastroenterology

Basal Autophagy and Feedback Activation of Akt Are Associated with Resistance to Metformin-Induced Inhibition of Hepatic Tumor Cell Growth

(2015) Hua Yang et al.   PLoS One

Akt Phosphorylation and Regulation of Transketolase Is a Nodal Point for Amino Acid Control of Purine Synthesis

(2014) Arindam Saha et al.   MOLECULAR CELL

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?

(2014) H Lincet et al.   ONCOGENE

Low glucose promotes CD133mAb-elicited cell death via inhibition of autophagy in hepatocarcinoma cells

(2013) Haiyang Chen et al.   CANCER LETTERS

A Fast Workflow for Identification and Quantification of Proteomes

(2013) Chen Ding et al.   MOLECULAR & CELLULAR PROTEOMICS

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

Proteome-wide profiling of activated transcription factors with a concatenated tandem array of transcription factor response elements

(2013) C. Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear EGFR as a molecular target in cancer

(2013) Toni M. Brand et al.   RADIOTHERAPY AND ONCOLOGY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Metabolic changes in cancer: beyond the Warburg effect

(2012) W. Wu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Analysis of the Human Endogenous Coregulator Complexome

(2011) Anna Malovannaya et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

(2011) C Alberti et al.   ONCOGENE

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

(2009) Mohamed IF Shariff et al.   Expert Review of Gastroenterology & Hepatology

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

(2008) D. Y. Chiang et al.   CANCER RESEARCH

Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

(2008) Nilkantha Sen et al.   NATURE CELL BIOLOGY