标题
The role of autophagy in maintaining intestinal mucosal barrier
作者
关键词
-
出版物
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-04-25
DOI
10.1002/jcp.28722
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- DOP08 The regulatory landscape of intestinal cells—investigating the transcriptional effect of autophagy impairment observed in Crohn’s disease using organoid and network biology approaches
- (2019) A Treveil et al. Journal of Crohns & Colitis
- Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine
- (2018) Elizabeth Delorme-Axford et al. Autophagy
- Deficiency of Atg6 impairs beneficial effect of metformin on intestinal stem cell aging in Drosophila
- (2018) Hyun-Jin Na et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii -Mediated Inflammation
- (2018) Elise Burger et al. Cell Host & Microbe
- Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
- (2018) Johanna Pott et al. Cell Host & Microbe
- The autophagic network and cancer
- (2018) Marissa D. Rybstein et al. NATURE CELL BIOLOGY
- Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
- (2018) Eric C. Martens et al. NATURE REVIEWS MICROBIOLOGY
- Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease
- (2018) Shu-Ling Wang et al. Frontiers in Immunology
- Curcumin: A naturally occurring autophagy modulator
- (2018) Abolfazl Shakeri et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Autophagy maintains stem cells and intestinal homeostasis in Drosophila
- (2018) Péter Nagy et al. Scientific Reports
- Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury
- (2018) Maria Ruart et al. JOURNAL OF HEPATOLOGY
- The protection role of Atg16l1 in CD11c + dendritic cells in murine colitis
- (2017) Hong Zhang et al. IMMUNOBIOLOGY
- Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers
- (2017) Cong Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- New insights into autophagosome–lysosome fusion
- (2017) Shuhei Nakamura et al. JOURNAL OF CELL SCIENCE
- Autophagosome Maturation and Fusion
- (2017) Fulvio Reggiori et al. JOURNAL OF MOLECULAR BIOLOGY
- Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies
- (2017) Siew C Ng et al. LANCET
- Targeting Free Radicals in Oxidative Stress-Related Human Diseases
- (2017) Patrik Poprac et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration
- (2017) Jumpei Asano et al. Cell Reports
- Fine-tuning autophagy: from transcriptional to posttranslational regulation
- (2016) Joëlle Botti-Millet et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasiveEscherichia coliinfection
- (2016) Alexis Bretin et al. Autophagy
- Global patterns and trends in colorectal cancer incidence and mortality
- (2016) Melina Arnold et al. GUT
- NOD2 induces autophagy to control AIEC bacteria infectiveness in intestinal epithelial cells
- (2016) Anna Negroni et al. INFLAMMATION RESEARCH
- SalmonellaCo-opts Host Cell Chaperone-mediated Autophagy for Intracellular Growth
- (2016) Vikash Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory Bowel Disease Drugs: A Focus on Autophagy
- (2016) Kirsty M. Hooper et al. Journal of Crohns & Colitis
- The ATG16L1 risk allele associated with Crohn’s disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines
- (2016) M E Wildenberg et al. Mucosal Immunology
- The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
- (2016) Kotaro Tsuboyama et al. SCIENCE
- TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
- (2016) Eun A. Ra et al. Nature Communications
- The Mucosal Immune System and Its Regulation by Autophagy
- (2016) Agnieszka M. Kabat et al. Frontiers in Immunology
- Autophagy and oxidative stress in cardiovascular diseases
- (2015) Yu Mei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Secretory autophagy
- (2015) Marisa Ponpuak et al. CURRENT OPINION IN CELL BIOLOGY
- Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide
- (2015) J. L. Duan et al. FREE RADICAL RESEARCH
- Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation
- (2015) Prashant K. Nighot et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome
- (2015) T. Proikas-Cezanne et al. JOURNAL OF CELL SCIENCE
- P042. Response to corticosteroids in Ulcerative Colitis may be related to modulation of mTOR signaling pathway genes by microRNAs
- (2015) Journal of Crohns & Colitis
- Autophagy and autophagy-related proteins in the immune system
- (2015) Shusaku T Shibutani et al. NATURE IMMUNOLOGY
- The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer’s Disease
- (2015) Zhenzhen Liu et al. Oxidative Medicine and Cellular Longevity
- Autophagy in colorectal cancer: An important switch from physiology to pathology
- (2015) Florin Burada World Journal of Gastrointestinal Oncology
- Mo1778 Abnormal Activation of Crinophagy in Crohn's Disease Paneth Cells
- (2015) Elodie Thachil et al. GASTROENTEROLOGY
- Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells
- (2014) Ying Yang et al. AMINO ACIDS
- Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
- (2014) Wenjie Guo et al. Autophagy
- NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
- (2014) Marta Wlodarska et al. CELL
- Oxidative stress and autophagy: the clash between damage and metabolic needs
- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- Getting ready for building: signaling and autophagosome biogenesis
- (2014) A. Abada et al. EMBO REPORTS
- The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead
- (2014) Aleksandar D. Kostic et al. GASTROENTEROLOGY
- A Novel Role of Autophagy in Intestinal Epithelial Stem Cell Proliferation and Renewal
- (2014) S. Shaffiey et al. JOURNAL OF SURGICAL RESEARCH
- A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3
- (2014) Aditya Murthy et al. NATURE
- Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
- (2014) K. G. Lassen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation
- (2013) Bo Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
- (2013) Sandra Cabrera et al. Autophagy
- Energy deprivation by silibinin in colorectal cancer cells
- (2013) Komal Raina et al. Autophagy
- Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria
- (2013) Jamaal L. Benjamin et al. Cell Host & Microbe
- Autophagy and human diseases
- (2013) Peidu Jiang et al. CELL RESEARCH
- Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration
- (2013) Ciara Metcalfe et al. Cell Stem Cell
- Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy
- (2013) M. Selvakumaran et al. CLINICAL CANCER RESEARCH
- Autophagy proteins control goblet cell function by potentiating reactive oxygen species production
- (2013) Khushbu K Patel et al. EMBO JOURNAL
- Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice From Salmonella Infection
- (2013) Kara L. Conway et al. GASTROENTEROLOGY
- Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy
- (2013) Hang Thi Thu Nguyen et al. GASTROENTEROLOGY
- A Critical Role for TLR4 Induction of Autophagy in the Regulation of Enterocyte Migration and the Pathogenesis of Necrotizing Enterocolitis
- (2013) M. D. Neal et al. JOURNAL OF IMMUNOLOGY
- Paneth cells as a site of origin for intestinal inflammation
- (2013) Timon E. Adolph et al. NATURE
- Emerging regulation and functions of autophagy
- (2013) Patricia Boya et al. NATURE CELL BIOLOGY
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease
- (2012) Lyndsay Murrow et al. Annual Review of Pathology-Mechanisms of Disease
- Resistance of colon cancer to 5-fluorouracil may be overcome by combination with chloroquine, an in vivo study
- (2012) Kazuhito Sasaki et al. ANTI-CANCER DRUGS
- Autophagy is active in normal colon mucosa
- (2012) Jean-Francois Groulx et al. Autophagy
- Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota
- (2012) Hachung Chung et al. CELL
- Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response
- (2012) Pierre Lapaquette et al. CELLULAR MICROBIOLOGY
- Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut
- (2012) Nadine Wittkopf et al. Clinical & Developmental Immunology
- Common alleles that influence autophagy and the risk for inflammatory bowel disease
- (2012) Agnès Gardet et al. CURRENT OPINION IN IMMUNOLOGY
- The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
- (2012) Javier Muñoz et al. EMBO JOURNAL
- Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells
- (2012) HISANORI MIKI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity
- (2012) Koutaro Ishibashi et al. MOLECULAR BIOLOGY OF THE CELL
- mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
- (2012) Ömer H. Yilmaz et al. NATURE
- Paneth Cells and Necrotizing Enterocolitis: A Novel Hypothesis for Disease Pathogenesis
- (2012) Steven J. McElroy et al. Neonatology
- Tight Junction Pore and Leak Pathways: A Dynamic Duo
- (2011) Le Shen et al. Annual Review of Physiology
- Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
- (2011) Jacques Amar et al. EMBO Molecular Medicine
- Antimicrobial peptides important in innate immunity
- (2011) Andreas Cederlund et al. FEBS Journal
- Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection
- (2011) Netanya G. Sandler et al. GASTROENTEROLOGY
- Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review
- (2011) Natalie A. Molodecky et al. GASTROENTEROLOGY
- Crohn's disease: NOD2, autophagy and ER stress converge
- (2011) T. Fritz et al. GUT
- The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding
- (2011) Diane Mathis et al. IMMUNOLOGICAL REVIEWS
- A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
- (2011) Hua Tian et al. NATURE
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
- (2011) Charles L. Bevins et al. NATURE REVIEWS MICROBIOLOGY
- Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging
- (2011) D. R. Green et al. SCIENCE
- ER stress and the unfolded protein response in intestinal inflammation
- (2010) Michael A. McGuckin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis
- (2010) Andrew A. Maynard et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine
- (2010) Ken Cadwell et al. CELL
- LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
- (2010) Hilla Weidberg et al. EMBO JOURNAL
- The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease
- (2010) Susanne Billmann-Born et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
- (2010) Toshiro Sato et al. NATURE
- Eaten alive: a history of macroautophagy
- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
- Genome-wide association identifies multiple ulcerative colitis susceptibility loci
- (2010) Dermot P B McGovern et al. NATURE GENETICS
- Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease
- (2010) Jean Frédéric Colombel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Succession of microbial consortia in the developing infant gut microbiome
- (2010) J. E. Koenig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intestinal epithelial cells in inflammatory bowel diseases
- (2010) Giulia Roda WORLD JOURNAL OF GASTROENTEROLOGY
- Early but not late administration of glucagon-like peptide-2 following ileo-cecal resection augments putative intestinal stem cell expansion
- (2009) Aaron P. Garrison et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The paradox of autophagy and its implication in cancer etiology and therapy
- (2009) Avital Eisenberg-Lerner et al. APOPTOSIS
- Identification ofAtg5-dependent transcriptional changes and increases in mitochondrial mass inAtg5-deficient T lymphocytes
- (2009) Linda M. Stephenson et al. Autophagy
- A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease
- (2009) Ken Cadwell et al. Autophagy
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Paneth Cell Development, Differentiation, and Function: New Molecular Cues
- (2009) Thaddeus S. Stappenbeck GASTROENTEROLOGY
- Immune Responses to the Microbiota at the Intestinal Mucosal Surface
- (2009) Breck A. Duerkop et al. IMMUNITY
- STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
- (2009) Geethanjali Pickert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Proteomic Analyses of the Two Mucus Layers of the Colon Barrier Reveal That Their Main Component, the Muc2 Mucin, Is Strongly Bound to the Fcgbp Protein
- (2009) Malin E. V. Johansson et al. JOURNAL OF PROTEOME RESEARCH
- ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
- (2009) Chang Hwa Jung et al. MOLECULAR BIOLOGY OF THE CELL
- Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium
- (2008) Laurens G. van der Flier et al. Annual Review of Physiology
- Epithelial cell–cell junctions and plasma membrane domains
- (2008) Ben N.G. Giepmans et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Autophagy Gives a Nod and a Wink to the Inflammasome and Paneth Cells in Crohn's Disease
- (2008) Vojo Deretic et al. DEVELOPMENTAL CELL
- The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Jiefei Geng et al. EMBO REPORTS
- Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
- (2008) M C Arrieta et al. GUT
- The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
- (2008) C. M. Van Itallie et al. JOURNAL OF CELL SCIENCE
- Munc13-2−/−baseline secretion defect reveals source of oligomeric mucins in mouse airways
- (2008) Yunxiang Zhu et al. JOURNAL OF PHYSIOLOGY-LONDON
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
- (2008) S. Vaishnava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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