Targeting miR‐193a‐AML1‐ETO‐β‐catenin axis by melatonin suppresses the self‐renewal of leukaemia stem cells in leukaemia with t (8;21) translocation

Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug

(2018) Hamed Nosrati et al.   BIOORGANIC CHEMISTRY

A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia

(2018) Laixi Bi et al.   BMC CANCER

Melatonin disturbs SUMOylation-mediated crosstalk between c-Myc and nestin via MT1 activation and promotes the sensitivity of paclitaxel in brain cancer stem cells

(2018) Hyemin Lee et al.   JOURNAL OF PINEAL RESEARCH

Homoharringtonine synergy with oridonin in treatment of t(8; 21) acute myeloid leukemia

(2018) Weina Zhang et al.   Frontiers of Medicine

Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit+cardiac progenitor cells by promoting miR-675

(2016) Benzhi Cai et al.   JOURNAL OF PINEAL RESEARCH

Homoharringtonine combined with aclarubicin and cytarabine synergistically induces apoptosis in t(8;21) leukemia cells and triggers caspase-3-mediated cleavage of the AML1-ETO oncoprotein

(2016) Jiang Cao et al.   Cancer Medicine

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia

(2015) Chun-Wei Chen et al.   NATURE MEDICINE

Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup

(2014) M.-A. Hospital et al.   BLOOD

Melatonin and ubiquitin: what’s the connection?

(2014) Jerry Vriend et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Melatonin for prevention of metabolic side-effects of olanzapine in patients with first-episode schizophrenia: Randomized double-blind placebo-controlled study

(2014) Amirhossein Modabbernia et al.   JOURNAL OF PSYCHIATRIC RESEARCH

AML1-ETO mediates hematopoietic self-renewal and leukemogenesis through a COX/ -catenin signaling pathway

(2013) Y. Zhang et al.   BLOOD

Melatonin Signaling and Its Modulation of PfNF-YB Transcription Factor Expression in Plasmodium falciparum

(2013) Wânia Lima et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The inhibition of TNF-α-induced leucocyte apoptosis by melatonin involves membrane receptor MT1/MT2 interaction

(2013) Javier Espino et al.   JOURNAL OF PINEAL RESEARCH

Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway

(2012) Y. Li et al.   BLOOD

Preclinical Efficacy of Melatonin to Reduce Methotrexate-Induced Oxidative Stress and Small Intestinal Damage in Rats

(2012) Viswa Kalyan Kolli et al.   DIGESTIVE DISEASES AND SCIENCES

Melatonin uses in oncology: breast cancer prevention and reduction of the side effects of chemotherapy and radiation

(2012) Emilio J Sanchez-Barcelo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Targeting of AML1-ETO in t(8;21) Leukemia by Oridonin Generates a Tumor Suppressor-Like Protein

(2012) T. Zhen et al.   Science Translational Medicine

Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5′-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells

(2011) Wonil Koh et al.   JOURNAL OF PINEAL RESEARCH

A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

(2011) Jörg H. Stehle et al.   JOURNAL OF PINEAL RESEARCH

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Melatonin exerts differential actions on X-ray radiation-induced apoptosis in normal mice splenocytes and Jurkat leukemia cells

(2009) Seong Soon Jang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

(2009) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon- induced inhibitory signaling

(2007) Y. Lee et al.   BLOOD

Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARα

(2007) Oliver H. Krämer et al.   FASEB JOURNAL