Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5′-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells

Tanshinone IIA Induces Mitochondria Dependent Apoptosis in Prostate Cancer Cells in Association with an Inhibition of Phosphoinositide 3-Kinase/AKT Pathway

(2010) Suk-Hyun Won et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors

(2010) IM Pires et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells

(2010) Quein Ahn et al.   CANCER LETTERS

Targeting the checkpoint kinase Chk1 in cancer therapy

(2010) Callie Merry et al.   CELL CYCLE

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

(2010) Hiroyuki Niida et al.   EMBO JOURNAL

Metformin: Taking away the candy for cancer?

(2010) Mathilde Jalving et al.   EUROPEAN JOURNAL OF CANCER

Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells

(2010) Toran Sanli et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Apoptotic Effect of Quercetin on HT-29 Colon Cancer Cells via the AMPK Signaling Pathway

(2010) Hyeong-Jin Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF

(2010) Seán M. Kilbride et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition

(2010) Wen-bin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways

(2010) Kyoung Ja Kwon et al.   Journal of Clinical Neurology

Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)

(2010) Anna Leja-Szpak et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and Doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines

(2010) Lu-Lu Fan   WORLD JOURNAL OF GASTROENTEROLOGY

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

(2009) S. Fogarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death

(2009) Vanesa Martín et al.   CANCER LETTERS

Activation of the AMP-activated protein kinase–p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells

(2009) Yung-Chung Hsu et al.   CELLULAR SIGNALLING

Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

(2009) Seong Soo Joo et al.   JOURNAL OF PINEAL RESEARCH

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

(2009) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway

(2009) Sara Casado-Zapico et al.   JOURNAL OF PINEAL RESEARCH

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Targeting AMPK: A new therapeutic opportunity in breast cancer

(2008) Sirwan M. Hadad et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY