HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia
出版年份 2019 全文链接
标题
HSP70/HSF1 axis, regulated
via
a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF CANCER
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-05-02
DOI
10.1002/ijc.32383
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Regulation of the mammalian heat shock factor 1
- (2017) Sharadha Dayalan Naidu et al. FEBS Journal
- Clinical and Laboratory Prognostic Indicators in Chronic Lymphocytic Leukemia
- (2017) Elizabeth M. Sagatys et al. Cancer Control
- Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins
- (2016) Federica Frezzato et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases
- (2016) Sharadha Dayalan Naidu et al. MOLECULAR AND CELLULAR BIOLOGY
- HSF1: Guardian of Proteostasis in Cancer
- (2016) Chengkai Dai et al. TRENDS IN CELL BIOLOGY
- Fisetin Suppresses Macrophage-Mediated Inflammatory Responses by Blockade of Src and Syk
- (2015) Jun Ho Kim et al. Biomolecules & Therapeutics
- Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter
- (2015) J. A. Kim et al. CARCINOGENESIS
- Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival
- (2015) Valentina Trimarco et al. Oncotarget
- Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole
- (2014) Federica Frezzato et al. BRITISH JOURNAL OF HAEMATOLOGY
- Proteotoxicity is not the reason for the dependence of cancer cells on the major chaperone Hsp70
- (2014) Teresa A Colvin et al. CELL CYCLE
- Pleiotropic Role of HSF1 in Neoplastic Transformation
- (2014) Natalia Vydra et al. CURRENT CANCER DRUG TARGETS
- Flavonoids in modulation of cell survival signalling pathways
- (2014) Mohammad Lukman Mansuri et al. Genes and Nutrition
- HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy
- (2014) XIAOXIA WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia
- (2013) Huayuan Zhu et al. ANNALS OF HEMATOLOGY
- Hsp90 Inhibitor SNX-7081 Dysregulates Proteins Involved with DNA Repair and Replication and the Cell Cycle in Human Chronic Lymphocytic Leukemia (CLL) Cells
- (2013) Yiping Che et al. JOURNAL OF PROTEOME RESEARCH
- Inhibition of HSP70: A challenging anti-cancer strategy
- (2012) Anastasia R. Goloudina et al. CANCER LETTERS
- Heat shock factors: integrators of cell stress, development and lifespan
- (2010) Malin Åkerfelt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Functional Protein Network Activation Mapping Reveals New Potential Molecular Drug Targets for Poor Prognosis Pediatric BCP-ALL
- (2010) Benedetta Accordi et al. PLoS One
- Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance
- (2009) A. V. Kurtova et al. BLOOD
- Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia
- (2008) L. Trentin et al. BLOOD
- Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks
- (2008) Polychronis Kotoglou et al. CELL STRESS & CHAPERONES
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