Rats bred for high anxiety exhibit distinct fear‐related coping behavior, hippocampal physiology, and synaptic plasticity‐related gene expression

Running exercise mitigates the negative consequences of chronic stress on dorsal hippocampal long-term potentiation in male mice

(2018) Roxanne M. Miller et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy

(2018) Allie J. Widman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine Neurons Reflect the Uncertainty in Fear Generalization

(2018) Yong S. Jo et al.   NEURON

Selectively Bred Rats Provide a Unique Model of Vulnerability to PTSD-Like Behavior and Respond Differentially to FGF2 Augmentation Early in Life

(2017) Katherine E Prater et al.   NEUROPSYCHOPHARMACOLOGY

Hippocampal GR- and CB1-mediated mGluR5 differentially produces susceptibility and resilience to acute and chronic mild stress in rats

(2017) Hongli Sun et al.   NEUROSCIENCE

Expression of BDNF and trkB in the hippocampus of a rat genetic model of vulnerability (Roman low-avoidance) and resistance (Roman high-avoidance) to stress-induced depression

(2017) M. Pina Serra et al.   Brain and Behavior

DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction

(2016) D. Zou et al.   CURRENT MOLECULAR MEDICINE

The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent

(2016) Janna Aarse et al.   HIPPOCAMPUS

Midbrain circuits for defensive behaviour

(2016) Philip Tovote et al.   NATURE

Direct Ventral Hippocampal-Prefrontal Input Is Required for Anxiety-Related Neural Activity and Behavior

(2016) Nancy Padilla-Coreano et al.   NEURON

Altered metabolic activity in the developing brain of rats predisposed to high versus low depression-like behavior

(2016) C.R. McCoy et al.   NEUROSCIENCE

Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety

(2015) Joshua L. Cohen et al.   DEVELOPMENTAL NEUROSCIENCE

Maternal Care Differentially Affects Neuronal Excitability and Synaptic Plasticity in the Dorsal and Ventral Hippocampus

(2015) Huy-Binh Nguyen et al.   NEUROPSYCHOPHARMACOLOGY

Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats

(2015) M.E. Glover et al.   NEUROSCIENCE

The adaptive and maladaptive continuum of stress responses – a hippocampal perspective

(2015) Deepika Suri et al.   REVIEWS IN THE NEUROSCIENCES

An excitatory synapse hypothesis of depression

(2015) Scott M. Thompson et al.   TRENDS IN NEUROSCIENCES

Lesions to the CA2 region of the hippocampus impair social memory in mice

(2014) Erica L. Stevenson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amygdala Inputs to the Ventral Hippocampus Bidirectionally Modulate Social Behavior

(2014) A. C. Felix-Ortiz et al.   JOURNAL OF NEUROSCIENCE

The hippocampal CA2 region is essential for social memory

(2014) Frederick L. Hitti et al.   NATURE

Estradiol replacement extends the window of opportunity for hippocampal function

(2014) Lindsey C. Vedder et al.   NEUROBIOLOGY OF AGING

Male rats that differ in novelty exploration demonstrate distinct patterns of sexual behavior.

(2013) Jennifer A. Cummings et al.   BEHAVIORAL NEUROSCIENCE

Active Avoidance Learning Requires Prefrontal Suppression of Amygdala-Mediated Defensive Reactions

(2013) J. M. Moscarello et al.   JOURNAL OF NEUROSCIENCE

Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty

(2013) Shelly B. Flagel et al.   NEUROPHARMACOLOGY

High novelty-seeking rats are resilient to negative physiological effects of the early life stress

(2013) Sarah M. Clinton et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

DNA Methylation in the Developing Hippocampus and Amygdala of Anxiety-Prone versus Risk-Taking Rats

(2012) Rebecca K. Simmons et al.   DEVELOPMENTAL NEUROSCIENCE

Estradiol-induced increase in novel object recognition requires hippocampal NR2B-containing NMDA receptors

(2012) Lindsey C. Vedder et al.   HIPPOCAMPUS

Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats

(2012) Marco Pignatelli et al.   NEUROPHARMACOLOGY

Seizure Susceptibility and Epileptogenesis in a Rat Model of Epilepsy and Depression Co-Morbidity

(2012) S Alisha Epps et al.   NEUROPSYCHOPHARMACOLOGY

Differential hippocampal neuron density between inbred Roman high- (low anxious) and low-avoidance (high anxious) rats

(2012) A. Garcia-Falgueras et al.   NEUROSCIENCE LETTERS

Neonatal fibroblast growth factor treatment enhances cocaine sensitization

(2012) Sarah M. Clinton et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Variations in postnatal maternal care and the epigenetic regulation of metabotropic glutamate receptor 1 expression and hippocampal function in the rat

(2012) R. C. Bagot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational Concepts of mGluR5 in Synaptic Diseases of the Brain

(2012) Thomas M. Piers et al.   Frontiers in Pharmacology

High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups

(2011) Ilan A. Kerman et al.   BRAIN RESEARCH

Developmental underpinnings of differences in rodent novelty-seeking and emotional reactivity

(2011) Sarah M. Clinton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

P.2.b.009 The melanin-concentrating hormone system and emotional-like behaviour

(2011) M.J. García-Fuster et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety

(2011) Larry S Zweifel et al.   NATURE NEUROSCIENCE

Towards a glutamate hypothesis of depression

(2011) Gerard Sanacora et al.   NEUROPHARMACOLOGY

Novelty-seeking behavior predicts vulnerability in a rodent model of depression

(2011) Kristen A. Stedenfeld et al.   PHYSIOLOGY & BEHAVIOR

Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals

(2011) C. A. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inborn differences in environmental reactivity predict divergent diurnal behavioral, endocrine, and gene expression rhythms

(2011) Ilan A. Kerman et al.   PSYCHONEUROENDOCRINOLOGY

Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

(2011) Jennifer A Cummings et al.   Biology of Sex Differences

Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse

(2009) M. J. García-Fuster et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A New Role for FGF2 as an Endogenous Inhibitor of Anxiety

(2009) J. A. Perez et al.   JOURNAL OF NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Rapid avoidance acquisition in Wistar–Kyoto rats

(2008) R.J. Servatius et al.   BEHAVIOURAL BRAIN RESEARCH

Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11β-hydroxysteroid dehydrogenase type 2

(2008) P. J. Lucassen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Maternal Care and Hippocampal Plasticity: Evidence for Experience-Dependent Structural Plasticity, Altered Synaptic Functioning, and Differential Responsiveness to Glucocorticoids and Stress

(2008) D. L. Champagne et al.   JOURNAL OF NEUROSCIENCE

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

(2008) G Shaltiel et al.   MOLECULAR PSYCHIATRY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats

(2008) Brooke A. Davis et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Local facilitation of hippocampal metabotropic glutamate receptor-dependent long-term depression by corticosterone and dexamethasone

(2008) Francis Chaouloff et al.   PSYCHONEUROENDOCRINOLOGY

Prenatal stress does not alter innate novelty-seeking behavioral traits, but differentially affects individual differences in neuroendocrine stress responsivity

(2008) Sarah Clinton et al.   PSYCHONEUROENDOCRINOLOGY

Rats selectively-bred for behavior related to affective disorders: Proclivity for intake of alcohol and drugs of abuse, and measures of brain monoamines

(2007) J.M. Weiss et al.   BIOCHEMICAL PHARMACOLOGY

Environmental novelty is signaled by reduction of the hippocampal theta frequency

(2007) A. Jeewajee et al.   HIPPOCAMPUS