Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's

α-synuclein genetic variability: A biomarker for dementia in Parkinson disease

(2016) Ilaria Guella et al.   ANNALS OF NEUROLOGY

Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression

(2016) Albert A. Davis et al.   NEUROBIOLOGY OF AGING

Gaucher disease types 1 and 3: Phenotypic characterization of large populations from the ICGG Gaucher Registry

(2015) Gregory A. Grabowski et al.   AMERICAN JOURNAL OF HEMATOLOGY

Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson’s disease

(2015) Joseph J. Locascio et al.   BRAIN

Glucocerebrosidase activity in Parkinson’s disease with and withoutGBAmutations

(2015) Roy N. Alcalay et al.   BRAIN

Impact of glucocerebrosidase mutations on motor and nonmotor complications in Parkinson's disease

(2015) Tomoko Oeda et al.   NEUROBIOLOGY OF AGING

Differential effects of severe vs mild GBA mutations on Parkinson disease

(2015) Z. Gan-Or et al.   NEUROLOGY

Glucocerebrosidase is shaking up the synucleinopathies

(2014) Marina Siebert et al.   BRAIN

GBA-associated Parkinson's disease: Reduced survival and more rapid progression in a prospective longitudinal study

(2014) Kathrin Brockmann et al.   MOVEMENT DISORDERS

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

Predictors of dementia in Parkinson's disease; findings from a 5-year prospective study using the SCOPA-COG

(2014) Kangdi Zhu et al.   PARKINSONISM & RELATED DISORDERS

iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis

(2014) David C. Schöndorf et al.   Nature Communications

Sleep and Circadian Rhythm Regulation in Early Parkinson Disease

(2014) David P. Breen et al.   JAMA Neurology

Glucocerebrosidase mutations influence the natural history of Parkinson’s disease in a community-based incident cohort

(2013) Sophie E. Winder-Rhodes et al.   BRAIN

Functional analysis of 11 novel GBA alleles

(2013) Erika Malini et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Determinants of delayed diagnosis in Parkinson’s disease

(2013) David P. Breen et al.   JOURNAL OF NEUROLOGY

The CamPaIGN study of Parkinson's disease: 10-year outlook in an incident population-based cohort

(2013) Caroline H Williams-Gray et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study

(2013) H. Ding et al.   NEUROLOGY

Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

(2012) Matthew E. Gegg et al.   ANNALS OF NEUROLOGY

α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease

(2012) Beate Ritz et al.   PLoS One

Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing

(2011) Valerie Cullen et al.   ANNALS OF NEUROLOGY

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2

(2011) Nathan Pankratz et al.   ANNALS OF NEUROLOGY

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

Is E326K glucocerebrosidase a polymorphic or pathological variant?

(2011) Benjamin Liou et al.   MOLECULAR GENETICS AND METABOLISM

Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study

(2011) Hongliu Ding et al.   MOVEMENT DISORDERS

CNS expression of glucocerebrosidase corrects  -synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

(2011) S. P. Sardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease

(2010) Suzanne Lesage et al.   HUMAN MOLECULAR GENETICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort

(2009) Caroline H. Williams-Gray et al.   BRAIN

A longitudinal program for biomarker development in Parkinson's disease: A feasibility study

(2009) Bernard Ravina et al.   MOVEMENT DISORDERS

Chipping away at diagnostics for neurodegenerative diseases

(2009) Clemens R. Scherzer   NEUROBIOLOGY OF DISEASE

Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease

(2009) S. Hoops et al.   NEUROLOGY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA)

(2008) Kathleen S. Hruska et al.   HUMAN MUTATION

Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset

(2008) W. C. Nichols et al.   NEUROLOGY

Genotype-phenotype correlations between GBA mutations and Parkinson disease risk and onset

(2008) Z. Gan-Or et al.   NEUROLOGY