Review
Public, Environmental & Occupational Health
Tobias M. Appel, Natalia Quijano-Martinez, Elsa De La Cadena, Maria F. Mojica, Maria Virginia Villegas
Summary: Species of Raoultella and Klebsiella share many similarities and are practically indistinguishable in clinical microbiology laboratories due to technological limitations. There has been an increase in case reports of human Raoultella infections since the late 2000s, leading some authors to suggest Raoultella spp. as rare and/or emerging pathogens. Further studies are needed to clarify the epidemiology and clinical relevance of human Raoultella infections, as well as the impact of advancements in identification techniques on the reported cases. Raoultella spp. may be more underdiagnosed than considered rare or emerging pathogens.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Joana Cohen, Mohsin Altaf, Muhammad Mushtaq, Dustin Stanley
Summary: Raoultella planticola is a rare gram-negative, aerobic bacteria found in soil and water, with few case reports. This study presents a case of acute cystitis caused by R. planticola in a female patient with atrial fibrillation and recurrent UTIs.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Review
Pharmacology & Pharmacy
James M. Hungerford
Summary: Histamine intoxications occur when the histamine-metabolizing enzymes in the human body are compromised, leading to symptoms similar to those of endogenous histamine release caused by allergies or infections. While exogenous histamine is responsible for scombrotoxin fish poisoning, it is essential for immune responses, gastric acid regulation, and neurotransmission within the physiological range. Proper handling and monitoring of fish products are crucial to prevent high histamine levels, which can be detected through various screening methods including HPLC and commercial test kits.
Article
Zoology
Lu-Chao Lv, Yao-Yao Lu, Xun Gao, Wan-Yun He, Ming-Yi Gao, Kai-Bin Mo, Jian-Hua Liu
Summary: This study characterized NDM-5-producing Enterobacteriaceae from aquatic products in Guangzhou, China, identifying bla(NDM-5) in Citrobacter freundii and Escherichia coli strains on various plasmids. The transfer of bla(NDM-5) between different plasmids was likely facilitated by the Tn7051 transposon, expanding the transmission vectors of this carbapenemase gene.
ZOOLOGICAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Gregory A. Ballash, Amy L. Albers, Dixie F. Mollenkopf, Emily Sechrist, Rachael J. Adams, Thomas E. Wittum
Summary: Fresh retail meat products, including processed ones, are important sources of zoonotic foodborne pathogens and antimicrobial resistant bacteria. A high proportion of these products were found to be contaminated with MRSA, Salmonella, and various types of antibiotic resistant bacteria, with some even harboring epidemic carbapenemase-producing genotypes.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Applied
Heba Mohamed Mohamed El-Sherbiny, Khalid Ibrahim Sallam
Summary: The study evaluated the residual metal content and potential health risks posed by consumption of European sardine and Atlantic mackerel samples collected from the Mediterranean Sea Coast, Egypt. Results showed a significant increase in lead content after grilling mackerel, but the estimated daily intakes of the three metals in cooked fish samples were below approved limits, indicating no health risks for general consumers.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Infectious Diseases
Paulo Victor Batista Marini, Eliandro Reis Tavares, Cintia Werner Motter, Leticia Busato Migliorini, Romario Oliveira de Sales, Nayara Helisandra Fedrigo, Danielle Rosani Shinohara, Mariangela Hungria, Sueli Fumie Yamada-Ogatta, Maria Cristina Bronharo Tognim
Summary: In this study, the whole genome sequence of a Brazilian isolate of R. planticola and the genomic context of antibiotic resistance markers were reported. The isolate coharbored multiple antibiotic resistance genes, including bla(KPC-2), bla(NDM-1), and bla(CTX-M-15), which were associated with plasmids and mobile genetic elements. This comprehensive knowledge is crucial for implementing control measures against the rapid dissemination of this neglected microorganism and its genetic resistance background.
MICROBIAL DRUG RESISTANCE
(2023)
Article
Environmental Sciences
Seyda Fikirdesici Ergen, Ahmet Altindag, Yavuz Selim Bas
Summary: Due to the increasing harmful effects of metal(loid)s over time, it has become important to increase environmental awareness in environmental studies. The cumulative presence of metal(loid)s in nature, their interactions with each other, and the risks posed by fish consumption for human health are crucial to investigate. This study determined the concentrations of different metals in muscle and gill tissues of two types of fish and assessed the health risks of consuming these fish. It was found that the concentrations of certain metals exceeded the limit values and there was a high correlation between certain metal(loid)s, posing a risk to public health.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2023)
Review
Toxicology
Cesare de Gregorio, Giuseppe Ferrazzo, Ioanna Koniari, Nicholas G. Kounis
Summary: Scombroid syndrome is a toxic illness caused by ingestion of improperly stored fish contaminated by histamine-producing Gram-negative bacteria, leading to myocardial ischemia and potentially acute coronary syndrome in some patients. Current studies suggest scombroid-related ACS as a benign condition, except for patients with a history of coronary artery disease, previous ACS, or anaphylaxis. Hemodynamic failure in the acute stage is a potential concern even in apparently healthy individuals.
CLINICAL TOXICOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Evelyn Pereira, Elisa L. Elliot, Lauren Shade Singleton, Mark Otto, Adiam Tesfai, Matthew Doyle, Heather Hawk, Steven Bloodgood, Ronald A. Benner, Mary P. Ross, Allison Scott, Matthew C. Kristof, Teresa Fox, Brandon Bridgman, Nicholas Long, Kimberly Livsey, Alister Rubenstein, Kimberly Garner, David Nicholas, Yayu Chuang, Brendalee Viveiros, Christopher Waggener, Karl Klontz, Stelios Viazis
Summary: Scombrotoxin fish poisoning (SFP) outbreak linked to imported tuna. Sensory evaluation and chemical testing used to analyze imported tuna samples. Traceback, laboratory, and epidemiologic data utilized to protect public health. Challenges highlighted in SFP outbreaks associated with imported foods.
JOURNAL OF FOOD PROTECTION
(2021)
Review
Medicine, General & Internal
Roshan M. Lalmalani, Jaryl H. S. Gan, Simon Stacey
Summary: Scombroid is a foodborne illness caused by improper handling of fish, resulting in high histamine levels. This study reports two cases in Singapore, where a father and son developed symptoms suggestive of Scombroid after consuming imported tuna from Vietnam. The diagnosis was confirmed by elevated histamine levels in the fish. The paper discusses the pathophysiology, signs, symptoms, and management of Scombroid.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Nursing
Juan M. Gonzalez, Stephen McGhee, Johis Ortega
Summary: Scombroid poisoning is a common fish-borne related illness that can mimic fish allergies, leading to misdiagnosis. Nurse practitioners should be familiar with its presentation and management.
JNP-JOURNAL FOR NURSE PRACTITIONERS
(2021)
Article
Medicine, General & Internal
Roger Taylor, Joshua Burg, Nnennaya Opara
Summary: Scombroid poisoning is a common form of food poisoning caused by high histamine content in fresh, canned, or smoked fish due to improper handling and storage, with a short incubation period and severe symptoms.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Review
Cardiac & Cardiovascular Systems
Giuseppe Ferrazzo, Silvia Perfetti, Ioanna Koniari, Gianluca Di Bella, Nicholas G. Kounis, Cesare de Gregorio
Summary: Ingesting mistreated fish products can cause scombroid syndrome, a histaminergic illness. This syndrome usually manifests as rash, gastrointestinal and breathing problems, hypotension, and other histamine-related symptoms. While cardiac complications are rare, some patients experience chest pain similar to acute coronary syndrome upon admission. The underlying mechanism appears to involve transient coronary artery vasospasm. We conducted a literature search from 1997 to 2022 and identified 18 studies with 25 patients suspected of having ischemic heart scombroid syndrome. We discuss the main pathophysiological, clinical, diagnostic, therapeutic, and prognostic features, and propose a simplified diagnostic flowchart. Despite the potential for hemodynamic instability during the acute phase, even in young patients, the prognosis is generally favorable.
GIORNALE ITALIANO DI CARDIOLOGIA
(2023)
Article
Dermatology
Anja Ziegler, Eman Hamza, Sigridur Jonsdottir, Claudio Rhyner, Bettina Wagner, Gertraud Schupbach, Vilhjalmur Svansson, Sigurbjorg Torsteinsdottir, Eliane Marti
VETERINARY DERMATOLOGY
(2018)
Article
Immunology
Hanaa Ahmed-Hassan, Mohamed Sarjoon Abdul-Cader, Maha Ahmed Sabry, Eman Hamza, Shayan Sharif, Eva Nagy, Mohamed Faizal Abdul-Careem
Article
Virology
Hanaa Ahmed-Hassan, Mohamed Sarjoon Abdul-Cader, Upasama De Silva Senapathi, Maha Ahmed Sabry, Eman Hamza, Eva Nagy, Shayan Sharif, Mohamed Faizal Abdul-Careem
Article
Virology
Hanaa Ahmed-Hassan, Mohamed Sarjoon Abdul-Cader, Maha Ahmed Sabry, Eman Hamza, Mohamed Faizal Abdul-Careem
Article
Multidisciplinary Sciences
Mahmoud Elhariri, Dalia Hamza, Rehab Elhelw, Eman Hamza
SCIENTIFIC REPORTS
(2018)
Article
Food Science & Technology
Mahmoud Elhariri, Rehab Elhelw, Salah Selim, Mai Ibrahim, Dalia Hamza, Eman Hamza
FOODBORNE PATHOGENS AND DISEASE
(2020)
Article
Public, Environmental & Occupational Health
Dalia Hamza, Sohad Dorgham, Elshaimaa Ismael, Sherein Ismail Abd El-Moez, Mahmoud Elhariri, Rehab Elhelw, Eman Hamza
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2020)
Article
Infectious Diseases
Maha A. Sabry, Khaled A. Abdel-Moein, Fatma Abdel-Kader, Eman Hamza
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2020)
Article
Veterinary Sciences
Lucia Unger, Carlos Abril, Vinzenz Gerber, Vidhya Jagannathan, Christoph Koch, Eman Hamza
Summary: The study suggests that serum eca-miR-331 may not be sensitive or specific enough as a single biomarker for ES, but when combined with other miRNAs, it may be helpful for diagnosing ES.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Jeanne Cosandey, Eman Hamza, Vinzenz Gerber, Alessandra Ramseyer, Tosso Leeb, Vidhya Jagannathan, Klaudia Blaszczyk, Lucia Unger
Summary: MicroRNAs have been proposed as biomarkers for equine sarcoids, and this study aimed to validate their diagnostic and prognostic potential. Sex and breed influenced the expression levels of certain microRNAs, with one microRNA able to distinguish between horses affected by sarcoids and tumor-free horses.
Article
Immunology
Anja Ziegler, Judith Olzhausen, Eman Hamza, Ana Stojiljkovic, Michael H. Stoffel, Mattia Garbani, Claudio Rhyner, Eliane Marti
Summary: Allergen-specific immunotherapy (AIT) is the only curative approach for allergy treatment. Targeting dendritic cells (DC) can enhance the immunogenicity of antigens and improve AIT efficacy. This study aimed to evaluate the effects of antigen-targeting to equine DC and investigate the impact of immune modulators MPLA and CpG-ODN on the immune response. The results showed that fusion of DC-binding peptides to antigens enhanced antigen uptake and T-cell activation. The addition of immune modulators further enhanced the immune response by increasing or suppressing the production of different cytokines.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
(2022)
Article
Veterinary Sciences
E. Hamza, J. Cosandey, V Gerber, C. Koch, L. Unger
Summary: This study explored the use of three whole blood miRNAs in diagnosing and predicting the outcome of therapy for equine sarcoid (ES) disease. The results showed that eca-miR-127 could be used as a diagnostic biomarker for ES, while eca-miR-379 and eca-miR-432 might allow for monitoring the success of ES therapy.
VETERINARY RESEARCH COMMUNICATIONS
(2023)
Article
Agriculture, Dairy & Animal Science
Fatma Abdel-Kader, Eman Hamza, Khaled A. Abdel-Moein, Maha A. Sabry
Summary: This study identified virulent extended-spectrum cephalosporin-resistant Salmonella in poultry shops, with some strains showing resistance to carbapenems. These resistant strains may be transmitted to humans through food consumption.
Article
Agriculture, Dairy & Animal Science
Osman Mohamed Hamed, Maha Ahmed Sabry, Nawal A. Hassanain, Eman Hamza, Ahmed G. Hegazi, Marwa Badawy Salman