CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell

SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis

(2018) Fei Liu et al.   ONCOGENE

hnRNPDL extensively regulates transcription and alternative splicing

(2018) Ruth Zhen Li et al.   GENE

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

(2017) Sara K. Donnelly et al.   JOURNAL OF CELL BIOLOGY

Crk-like adapter protein is overexpressed in cervical carcinoma, facilitates proliferation, invasion and chemoresistance, and regulates Src and Akt signaling

(2016) Hong Ji et al.   Oncology Letters

Cervical Cancer Mortality Trends in China, 1991-2013, and Predictions for the Future

(2015) Pei-Ling Du et al.   Asian Pacific Journal of Cancer Prevention

Hsp90 regulates autophagy and plays a role in cancer therapy

(2015) Benli Wang et al.   TUMOR BIOLOGY

Alternative splicing in cancer: implications for biology and therapy

(2014) J Chen et al.   ONCOGENE

CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer

(2014) Lin Fu et al.   TUMOR BIOLOGY

CRKL promotes cell proliferation in gastric cancer and is negatively regulated by miR-126

(2013) Junqing Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Regulation of splicing by SR proteins and SR protein-specific kinases

(2013) Zhihong Zhou et al.   CHROMOSOMA

Effect of Rac1 downregulation mediated by shRNA on the biological behaviour of human cervical cancer cells

(2013) Ai Li Xu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials

(2013) Guglielmo Ronco et al.   LANCET

Hallmarks of alternative splicing in cancer

(2013) S Oltean et al.   ONCOGENE

Feasibility and safety of carboplatin plus paclitaxel as neoadjuvant chemotherapy for locally advanced cervical cancer: a pilot study

(2013) Roberto Angioli et al.   TUMOR BIOLOGY

Overexpression of CRKL correlates with malignant cell proliferation in breast cancer

(2013) Tingting Zhao et al.   TUMOR BIOLOGY

Embryonic stem cell-specific signature in cervical cancer

(2013) Jorge Organista-Nava et al.   TUMOR BIOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Pathway-Specific Analysis of Gene Expression Data Identifies the PI3K/Akt Pathway as a Novel Therapeutic Target in Cervical Cancer

(2012) Julie K. Schwarz et al.   CLINICAL CANCER RESEARCH

The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus

(2012) Zhihong Zhou et al.   MOLECULAR CELL

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cyclic AMP-dependent Protein Kinase Regulates the Alternative Splicing of Tau Exon 10

(2011) Jianhua Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional consequences of developmentally regulated alternative splicing

(2011) Auinash Kalsotra et al.   NATURE REVIEWS GENETICS

KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases

(2011) Chen Xie et al.   NUCLEIC ACIDS RESEARCH

Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis

(2011) Y.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non-Small Cell Lung Cancers

(2011) H. W. Cheung et al.   Cancer Discovery

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

(2010) C. J. David et al.   GENES & DEVELOPMENT

Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trial

(2010) Guglielmo Ronco et al.   LANCET ONCOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

(2009) Raymond B Birge et al.   Cell Communication and Signaling

Cancer-associated regulation of alternative splicing

(2009) Julian P Venables et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer

(2009) Y H Kim et al.   ONCOGENE

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

Alternative Splicing and Tumor Progression

(2008) Claudia Ghigna et al.   CURRENT GENOMICS

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE