Enhanced Oral Bioavailability, Anti-Tumor Activity and Hepatoprotective Effect of 6-Shogaol Loaded in a Type of Novel Micelles of Polyethylene Glycol and Linoleic Acid Conjugate

A novel formulation of [6]-gingerol: Proliposomes with enhanced oral bioavailability and antitumor effect

(2018) Qilong Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nine New Gingerols from the Rhizoma of Zingiber officinale and Their Cytotoxic Activities

(2018) Zezhi Li et al.   MOLECULES

Controlling and Predicting Nanoparticle Formation by Block Copolymer Directed Rapid Precipitations

(2018) Robert F. Pagels et al.   NANO LETTERS

Heat-induced conversion of gingerols to shogaols in ginger as affected by heat type (dry or moist heat), sample type (fresh or dried), temperature and time

(2017) Mun Yhung Jung et al.   FOOD SCIENCE AND BIOTECHNOLOGY

6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines

(2017) Ulana Kotowski et al.   PHYTOTHERAPY RESEARCH

Transcriptome analysis reveals the genetic basis underlying the biosynthesis of volatile oil, gingerols, and diarylheptanoids in ginger (Zingiber officinale Rosc.)

(2017) Yusong Jiang et al.   Botanical Studies

Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability

(2016) Hui-yun Zhang et al.   ACTA PHARMACOLOGICA SINICA

Preparation and evaluation of icariside II-loaded binary mixed micelles using Solutol HS15 and Pluronic F127 as carriers

(2016) Jian Hou et al.   DRUG DELIVERY

Improved oral bioavailability and anticancer efficacy on breast cancer of paclitaxel via Novel Soluplus ® —Solutol ® HS15 binary mixed micelles system

(2016) Jian Hou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Quercetin-loaded freeze-dried nanomicelles: Improving absorption and anti-glioma efficiency in vitro and in vivo

(2016) Gang Wang et al.   JOURNAL OF CONTROLLED RELEASE

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation

(2016) Hui-Yun Zhang et al.   Oncotarget

Critical determinant of intestinal permeability and oral bioavailability of pegylated all trans -retinoic acid prodrug-based nanomicelles: Chain length of poly (ethylene glycol) corona

(2015) Zhenbao Li et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms

(2015) Jung-Ju Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antioxidant, enzyme inhibitory and antiproliferative activity of polyphenolic-rich fraction of commercial dry ginger powder

(2015) Karunrat Sakulnarmrat et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Targeting Cancer Stem Cells in Breast Cancer: Potential Anticancer Properties of 6-Shogaol and Pterostilbene

(2015) Chi-Hao Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer

(2015) Sahdeo Prasad et al.   Gastroenterology Research and Practice

A PEG-Fmoc conjugate as a nanocarrier for paclitaxel

(2014) Peng Zhang et al.   BIOMATERIALS

6-Shogaol from Dried Ginger Inhibits Growth of Prostate Cancer Cells Both In Vitro and In Vivo through Inhibition of STAT3 and NF- B Signaling

(2014) A. Saha et al.   Cancer Prevention Research

Silybum marianum oil attenuates oxidative stress and ameliorates mitochondrial dysfunction in mice treated with D-galactose

(2014) Ying Dong et al.   Pharmacognosy Magazine

Enhanced oral bioavailability of capsaicin in mixed polymeric micelles: Preparation, in vitro and in vivo evaluation

(2014) Yuan Zhu et al.   Journal of Functional Foods

Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP

(2014) Angela X. Gao et al.   ACS Macro Letters

[6]-Shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2

(2013) Myoung Ok Kim et al.   CARCINOGENESIS

Glutathione conjugation attenuates biological activities of 6-dehydroshogaol from ginger

(2013) Guodong Zhang et al.   FOOD CHEMISTRY

Cytotoxic effect of novel Flammulina velutipes sterols and its oral bioavailability via mixed micellar nanoformulation

(2013) Chengxue Yi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

[6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway

(2012) Cheng Yao et al.   ACTA PHARMACOLOGICA SINICA

Vitamin E TPGS as a molecular biomaterial for drug delivery

(2012) Zhiping Zhang et al.   BIOMATERIALS

In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin

(2012) Feng Li et al.   FOOD CHEMISTRY

Formulation of Docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS2k) micelles for targeted and synergistic chemotherapy

(2011) Yu Mi et al.   BIOMATERIALS

Antioxidant and hepatoprotective activities of phenolic rich fraction of Seabuckthorn (Hippophae rhamnoides L.) leaves

(2011) D.T. Maheshwari et al.   FOOD AND CHEMICAL TOXICOLOGY

PLGA Nanoparticles Improve the Oral Bioavailability of Curcumin in Rats: Characterizations and Mechanisms

(2011) Xiaoxia Xie et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe (Part I)

(2010) Akitoshi Asami et al.   Journal of Natural Medicines

6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice

(2010) Hou Wu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

6-Shogaol inhibits monosodium urate crystal-induced inflammation – An in vivo and in vitro study

(2009) Evan Prince Sabina et al.   FOOD AND CHEMICAL TOXICOLOGY

Increased Growth Inhibitory Effects on Human Cancer Cells and Anti-inflammatory Potency of Shogaols from Zingiber officinale Relative to Gingerols

(2009) Shengmin Sang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2009) Jen-Yu Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

6-Shogaol induces apoptosis in human colorectal carcinoma cellsviaROS production, caspase activation, and GADD 153 expression

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH