Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction–induced memory enhancement

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(2018) Mark P. Mattson et al.   NATURE REVIEWS NEUROSCIENCE

Ludwigia octovalvis extract improves glycemic control and memory performance in diabetic mice

(2017) Wei-Sheng Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Orexin A induces bidirectional modulation of synaptic plasticity: Inhibiting long-term potentiation and preventing depotentiation

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Physical interaction between neurofibromin and serotonin 5-HT6receptor promotes receptor constitutive activity

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Tequila Regulates Insulin-Like Signaling and Extends Life Span inDrosophila melanogaster

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Fasting: Molecular Mechanisms and Clinical Applications

(2014) Valter D. Longo et al.   Cell Metabolism

The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism

(2014) M. Jacobshagen et al.   DEVELOPMENT

Safety and efficacy of idalopirdine, a 5-HT 6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial

(2014) David Wilkinson et al.   LANCET NEUROLOGY

Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth

(2014) Fanny Duhr et al.   Nature Chemical Biology

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Potential role of the 5-HT6 receptor in depression and anxiety: an overview of preclinical data

(2014) Anna Wesołowska   Pharmacological Reports

mTOR signaling and its roles in normal and abnormal brain development

(2014) Nobuyuki Takei et al.   Frontiers in Molecular Neuroscience

The anti-aging effects of Ludwigia octovalvis on Drosophila melanogaster and SAMP8 mice

(2013) Wei-Sheng Lin et al.   AGE

Rapamycin extends murine lifespan but has limited effects on aging

(2013) Frauke Neff et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2013) Marianne Leger et al.   Nature Protocols

Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis

(2013) Christoph Anacker et al.   NEUROPSYCHOPHARMACOLOGY

To Favor Survival Under Food Shortage, the Brain Disables Costly Memory

(2013) P.-Y. Placais et al.   SCIENCE

5-HT6receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia

(2012) Julie Meffre et al.   EMBO Molecular Medicine

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

(2012) Mark J. Millan et al.   NATURE REVIEWS DRUG DISCOVERY

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

(2012) J. Halloran et al.   NEUROSCIENCE

Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice

(2012) W. Peng et al.   Science Translational Medicine

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

(2012) Eric R Kandel   Molecular Brain

A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction

(2011) S. Fusco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Potential Molecular Link Between the Glucocorticoid and Serotonergic Signaling Systems

(2010) Virginia R. Falkenberg et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice

(2009) Alexis M. Stranahan et al.   HIPPOCAMPUS

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Sex Differences in High-fat Diet-induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

(2009) Ling-Ling Hwang et al.   Obesity

Mullerian inhibiting substance contributes to sex-linked biases in the brain and behavior

(2009) P.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric restriction improves memory in elderly humans

(2009) A. V. Witte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making a neuron: Cdk5 in embryonic and adult neurogenesis

(2009) Sebastian Jessberger et al.   TRENDS IN NEUROSCIENCES

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat

(2008) B Marcos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6

(2008) O Riccio et al.   MOLECULAR PSYCHIATRY

Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

(2008) Min Wei et al.   PLoS Genetics

Functional interaction between 5-HT6 receptors and hypothalamic–pituitary–adrenal axis: Cognitive implications

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