A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50

(2017) Ketan Malhotra et al.   Science Advances

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP‐dependent biogenesis pathway

(2016) Monika Sinzel et al.   EMBO REPORTS

GxxxG motifs hold the TIM23 complex together

(2015) Keren Demishtein-Zohary et al.   FEBS Journal

Cooperation of TOM and TIM23 Complexes during Translocation of Proteins into Mitochondria

(2015) Karin Waegemann et al.   JOURNAL OF MOLECULAR BIOLOGY

Unlocking the presequence import pathway

(2015) Christian Schulz et al.   TRENDS IN CELL BIOLOGY

The structure of Tim50(164–361) suggests the mechanism by which Tim50 receives mitochondrial presequences

(2015) Jingzhi Li et al.   Acta Crystallographica Section F-Structural Biology Communications

NMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain

(2014) Bytul Rahman et al.   FEBS LETTERS

Molecular Basis of the Dynamic Structure of the TIM23 Complex in the Mitochondrial Intermembrane Space

(2014) Rakhi Bajaj et al.   STRUCTURE

Signal recognition initiates reorganization of the presequence translocase during protein import

(2013) Oleksandr Lytovchenko et al.   EMBO JOURNAL

Molecular Insights Revealing Interaction of Tim23 and Channel Subunits of Presequence Translocase

(2013) G. Pareek et al.   MOLECULAR AND CELLULAR BIOLOGY

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes

(2012) Michael Gebert et al.   JOURNAL OF CELL BIOLOGY

Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex

(2011) Christian Schulz et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for the Function of Tim50 in the Mitochondrial Presequence Translocase

(2011) Xinguo Qian et al.   JOURNAL OF MOLECULAR BIOLOGY

Understanding the molecular mechanism of protein translocation across the mitochondrial inner membrane: Still a long way to go

(2010) Milit Marom et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences

(2010) Laura de la Cruz et al.   PROTEIN SCIENCE

Tim23–Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import

(2009) Yasushi Tamura et al.   JOURNAL OF CELL BIOLOGY

Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria

(2009) Dejana Mokranjac et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex

(2008) Lada Gevorkyan-Airapetov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quaternary Structure of the Mitochondrial TIM23 Complex Reveals Dynamic Association between Tim23p and Other Subunits

(2007) Nathan N. Alder et al.   MOLECULAR BIOLOGY OF THE CELL