Targeting Cancer with PCPA-Drug Conjugates: LSD1 Inhibition-Triggered Release of 4-Hydroxytamoxifen

Recent Progress in Histone Demethylase Inhibitors

(2016) Tom E. McAllister et al.   JOURNAL OF MEDICINAL CHEMISTRY

C–H activation enables a rapid structure–activity relationship study of arylcyclopropyl amines for potent and selective LSD1 inhibitors

(2016) Shin Miyamura et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection

(2015) Jens Hühner et al.   ELECTROPHORESIS

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

(2015) Madduri Srinivasarao et al.   NATURE REVIEWS DRUG DISCOVERY

ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation

(2015) U-H Park et al.   ONCOGENE

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients

(2014) Remco S Derr et al.   BMC CANCER

Lysine-Specific Demethylase 1-Selective Inactivators: Protein-Targeted Drug Delivery Mechanism

(2013) Daisuke Ogasawara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lysine Demethylases Inhibitors

(2011) Takayoshi Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

(2011) M. M. Singh et al.   NEURO-ONCOLOGY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

Pharmacogenomics of Tamoxifen Therapy

(2009) H. Brauch et al.   CLINICAL CHEMISTRY

A History of Cancer Chemotherapy

(2008) Vincent T. DeVita et al.   CANCER RESEARCH

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY