Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5

Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

(2016) Simone Cavadini et al.   NATURE

Targeted inhibition of the COP9 signalosome for treatment of cancer

(2016) Anita Schlierf et al.   Nature Communications

Crystal structure of the human COP9 signalosome

(2014) Gondichatnahalli M. Lingaraju et al.   NATURE

SCF ubiquitin ligase-targeted therapies

(2014) Jeffrey R. Skaar et al.   NATURE REVIEWS DRUG DISCOVERY

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

(2013) Aude Echalier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal–ligand interactions: An analysis of zinc binding groups using the Protein Data Bank

(2012) Kentaro Kawai et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism

(2012) Ethan D. Emberley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of COP9 signalosome in cancer

(2011) Mong-Hong Lee et al.   CELL CYCLE

Structural regulation of cullin-RING ubiquitin ligase complexes

(2011) David M Duda et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response

(2011) Y-H Lee et al.   ONCOGENE

JAB1/CSN5: a new player in cell cycle control and cancer

(2010) Terry J Shackleford et al.   Cell Division

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Matrix metalloproteinases: Fold and function of their catalytic domains

(2009) Cynthia Tallant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH