Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway
出版年份 2019 全文链接
标题
Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-03-29
DOI
10.1038/s41467-019-09491-5
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes
- (2016) Hiroshi Kobayashi et al. Nature Communications
- Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7
- (2015) Rachel H. Church et al. BIOCHEMICAL JOURNAL
- Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?
- (2015) Robert Erdmann et al. JOURNAL OF PATHOLOGY
- Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway
- (2015) Carolina Lavoz et al. JOURNAL OF PATHOLOGY
- BMP signalling: agony and antagony in the family
- (2015) Derek P. Brazil et al. TRENDS IN CELL BIOLOGY
- Cyclic Adenosine Monophosphate-Response Element–Binding Protein Mediates the Proangiogenic or Proinflammatory Activity of Gremlin
- (2013) Michela Corsini et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- MMP13 is a critical target gene during the progression of osteoarthritis
- (2013) Meina Wang et al. ARTHRITIS RESEARCH & THERAPY
- Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A
- (2011) A. J. Ehrlicher et al. NATURE
- Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage
- (2011) Heather Stanton et al. Nature Protocols
- Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
- (2010) S. Mitola et al. BLOOD
- NF-κB Signaling: Multiple Angles to Target OA
- (2010) Kenneth B. Marcu et al. CURRENT DRUG TARGETS
- Chronic exposure of bone morphogenetic protein-2 favors chondrogenic expression in human articular chondrocytes amplified in monolayer cultures
- (2010) S. Claus et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- (2010) Taku Saito et al. NATURE MEDICINE
- Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
- (2010) Siyoung Yang et al. NATURE MEDICINE
- The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse
- (2010) S.S. Glasson et al. OSTEOARTHRITIS AND CARTILAGE
- Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells
- (2010) T. Tetsunaga et al. OSTEOARTHRITIS AND CARTILAGE
- Matrix metalloproteinase 13âdeficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
- (2009) C. B. Little et al. ARTHRITIS AND RHEUMATISM
- Periodic knee injections of BMP-7 delay cartilage degeneration induced by excessive running in rats
- (2009) Ichiro Sekiya et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Modulating hedgehog signaling can attenuate the severity of osteoarthritis
- (2009) Alvin C Lin et al. NATURE MEDICINE
- Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
- (2009) Frank Echtermeyer et al. NATURE MEDICINE
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling
- (2009) Jin Nam et al. PLoS One
- Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
- (2009) Andre F Steinert et al. ARTHRITIS RESEARCH & THERAPY
- Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction
- (2008) Mei Zhu et al. ARTHRITIS AND RHEUMATISM
- Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice
- (2008) Mei Zhu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Focus on Molecules: Gremlin
- (2007) Robert J. Wordinger et al. EXPERIMENTAL EYE RESEARCH
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