标题
BCL-2 family isoforms in apoptosis and cancer
作者
关键词
-
出版物
Cell Death & Disease
Volume 10, Issue 3, Pages -
出版商
Springer Nature
发表日期
2019-02-21
DOI
10.1038/s41419-019-1407-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD
- (2018) Silvia Escudero et al. MOLECULAR CELL
- S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth
- (2018) Patrick Casara et al. Oncotarget
- BCL-XL directly modulates RAS signalling to favour cancer cell stemness
- (2017) Sophie de Carné Trécesson et al. Nature Communications
- Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax
- (2017) Joel D. Leverson et al. Cancer Discovery
- BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
- (2016) Fabien Llambi et al. CELL
- Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death
- (2016) Giampaolo Morciano et al. MOLECULAR BIOLOGY OF THE CELL
- Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models
- (2016) E. A. Punnoose et al. MOLECULAR CANCER THERAPEUTICS
- The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
- (2016) András Kotschy et al. NATURE
- BCL2 gene polymorphisms and splicing variants in chronic myeloid leukemia
- (2015) Vicent Guillem et al. LEUKEMIA RESEARCH
- Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy
- (2015) Joel D. Leverson et al. Science Translational Medicine
- First MCL-1-selective BH3 mimetics as potential therapeutics for targeted treatment of cancer
- (2015) S Besbes et al. Cell Death & Disease
- Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
- (2015) J D Leverson et al. Cell Death & Disease
- Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
- (2014) S. Suryani et al. CLINICAL CANCER RESEARCH
- The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis
- (2014) P. Bielli et al. EMBO REPORTS
- Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5′ splice site selection
- (2014) Pamela Bielli et al. NUCLEIC ACIDS RESEARCH
- RETRACTED: Long non-coding RNAINXSis a critical mediator ofBCL-XSinduced apoptosis
- (2014) Carlos DeOcesano-Pereira et al. NUCLEIC ACIDS RESEARCH
- Overexpression of Mcl-1L Splice Variant Is Associated with Poor Prognosis and Chemoresistance in Oral Cancers
- (2014) Vinayak Palve et al. PLoS One
- Chemical Perturbation of Mcl-1 Pre-mRNA Splicing to Induce Apoptosis in Cancer Cells
- (2013) Yang Gao et al. ACS Chemical Biology
- Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival
- (2013) Frédérique Braun et al. CELL CYCLE
- Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle
- (2013) Guillermo Risso et al. CELL CYCLE
- Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation
- (2013) Laura Vela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Interaction between Bcl-xLand the Voltage-dependent Anion Channel (VDAC) Promotes Mitochondrial Ca2+Uptake
- (2013) Huiya Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure-guided design of a selective BCL-XL inhibitor
- (2013) Guillaume Lessene et al. Nature Chemical Biology
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- MCL-1ES Induces MCL-1L-Dependent BAX- and BAK-Independent Mitochondrial Apoptosis
- (2013) Jae-Hong Kim et al. PLoS One
- BCL2 Suppresses PARP1 Function and Nonapoptotic Cell Death
- (2012) Chaitali Dutta et al. CANCER RESEARCH
- Disruption of the VDAC2–Bak interaction by Bcl-xS mediates efficient induction of apoptosis in melanoma cells
- (2012) M Plötz et al. CELL DEATH AND DIFFERENTIATION
- Phase II Study of Single-Agent Navitoclax (ABT-263) and Biomarker Correlates in Patients with Relapsed Small Cell Lung Cancer
- (2012) C. M. Rudin et al. CLINICAL CANCER RESEARCH
- Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis
- (2012) Colins O. Eno et al. MOLECULAR BIOLOGY OF THE CELL
- The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members
- (2012) Corentin Laulier et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
- (2012) Jean-Paul Decuypere et al. Cells
- Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes
- (2011) C. Laulier et al. CANCER RESEARCH
- Phase I Study of Navitoclax (ABT-263), a Novel Bcl-2 Family Inhibitor, in Patients With Small-Cell Lung Cancer and Other Solid Tumors
- (2011) Leena Gandhi et al. JOURNAL OF CLINICAL ONCOLOGY
- Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease
- (2011) Andrew W. Roberts et al. JOURNAL OF CLINICAL ONCOLOGY
- TCERG1 Regulates Alternative Splicing of the Bcl-x Gene by Modulating the Rate of RNA Polymerase II Transcription
- (2011) M. Montes et al. MOLECULAR AND CELLULAR BIOLOGY
- A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
- (2011) Fabien Llambi et al. MOLECULAR CELL
- Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak
- (2011) C Wang et al. ONCOGENE
- Molecular Basis of Bcl-XL-p53 Interaction: Insights from Molecular Dynamics Simulations
- (2011) Nagakumar Bharatham et al. PLoS One
- Mcl-1 levels need not be lowered for cells to be sensitized for ABT-263/737-induced apoptosis
- (2011) R Yamaguchi et al. Cell Death & Disease
- Molecular biology of Bax and Bak activation and action
- (2010) Dana Westphal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- BH3-only proteins: Orchestrators of apoptosis
- (2010) Aisha Shamas-Din et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis
- (2010) Michael J. Moore et al. CELL
- Mcl-1; the molecular regulation of protein function
- (2010) Luke W. Thomas et al. FEBS LETTERS
- Apoptosis Protection by Mcl-1 and Bcl-2 Modulation of Inositol 1,4,5-Trisphosphate Receptor-dependent Ca2+Signaling
- (2010) Emily F. Eckenrode et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells
- (2010) Tadi Satish Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The DNA Damage Response Pathway Regulates the Alternative Splicing of the Apoptotic MediatorBcl-x
- (2010) Lulzim Shkreta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
- (2010) Wyndham H Wilson et al. LANCET ONCOLOGY
- Anti-tumor activity of splice-switching oligonucleotides
- (2010) John A. Bauman et al. NUCLEIC ACIDS RESEARCH
- LDH correlation with survival in advanced melanoma from two large, randomised trials (Oblimersen GM301 and EORTC 18951)
- (2009) Sanjiv S. Agarwala et al. EUROPEAN JOURNAL OF CANCER
- MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death
- (2009) Jae-Hong Kim et al. FEBS LETTERS
- Heterogeneous Nuclear Ribonucleoprotein K Represses the Production of Pro-apoptotic Bcl-xSSplice Isoform
- (2009) Timothée Revil et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells
- (2009) Jeng-Jer Shieh et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Apoptosis induction by Bcl-2 proteins independent of the BH3 domain
- (2008) Amir M. Hossini et al. BIOCHEMICAL PHARMACOLOGY
- ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
- (2008) C. Tse et al. CANCER RESEARCH
- E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35
- (2008) G Merdzhanova et al. CELL DEATH AND DIFFERENTIATION
- MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth
- (2008) Julia Schultz et al. CELL RESEARCH
- Bcl2 Inhibits Abasic Site Repair by Down-regulating APE1 Endonuclease Activity
- (2008) Jinfeng Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antagonistic Effects of the SRp30c Protein and Cryptic 5 ′ Splice Sites on the Alternative Splicing of the Apoptotic Regulator Bcl-x
- (2008) Philippe Cloutier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein phosphatase 1 activation and alternative splicing of Bcl‐X and Mcl‐1 by EGCG + ibuprofen
- (2008) Myoung H. Kim JOURNAL OF CELLULAR BIOCHEMISTRY
- Novel Splicing Factor RBM25 Modulates Bcl-x Pre-mRNA 5' Splice Site Selection
- (2008) A. Zhou et al. MOLECULAR AND CELLULAR BIOLOGY
- Bcl2 Negatively Regulates DNA Double-Strand-Break Repair through a Nonhomologous End-Joining Pathway
- (2008) Qinhong Wang et al. MOLECULAR CELL
- JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
- (2008) Yongjie Wei et al. MOLECULAR CELL
- BCL-2 family antagonists for cancer therapy
- (2008) Guillaume Lessene et al. NATURE REVIEWS DRUG DISCOVERY
- The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology
- (2008) Claudio Hetz et al. TRENDS IN CELL BIOLOGY
- Bcl-2 Protein Family Members: Versatile Regulators of Calcium Signaling in Cell Survival and Apoptosis
- (2007) Yiping Rong et al. Annual Review of Physiology
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