Molecular docking, ADME/Tox prediction, and in vitro study of the cell growth inhibitory activity of five β-carboline alkaloids

Synthesis and antimicrobial activity of β-carboline derivatives with N 2 -alkyl modifications

(2018) Kenji Suzuki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Combining ligand-based and structure-based drug design approaches to study the structure-activity relationships of a β-carboline derivative series

(2018) T. Akabli et al.   STRUCTURAL CHEMISTRY

Recent insights into synthetic β -carbolines with anti-cancer activities

(2017) Sumit Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quantum chemical properties investigation and molecular docking analysis with DNA topoisomerase II of β-carboline indole alkaloids from Simaba guianensis: a combined experimental and theoretical DFT study

(2017) Renyer A. Costa et al.   STRUCTURAL CHEMISTRY

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

DNA binding and apoptotic induction ability of harmalol in HepG2: Biophysical and biochemical approaches

(2016) Sarita Sarkar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synthesis and Human Anticancer Cell Line Studies on Coumarin-β-carboline Hybrids as Possible Antimitotic Agents

(2016) S. Samundeeswari et al.   ChemistrySelect

Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability

(2015) Ahmed Kamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antimitotic drugs in the treatment of cancer

(2015) Rustelle Janse van Vuuren et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype

(2013) Lei Zhao et al.   PeerJ

Quantitative structure–activity relationship of antitumor and neurotoxic β-carbolines alkaloids: nine harmine derivatives

(2012) F. Lamchouri et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Inhibitory Effects of Herbal Alkaloids on the Tumor Necrosis Factor-α and Nitric Oxide Production in Lipopolysaccharide-Stimulated RAW264 Macrophages

(2011) Yoshimitsu Yamazaki et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-β-carboline)-3-carboxamides

(2010) Lilian T. Düsman Tonin et al.   BIOMEDICINE & PHARMACOTHERAPY

Search for alkaloids on callus culture of Passiflora alata

(2010) Michelli Wesz Machado et al.   BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1

(2010) Jing Zhang et al.   CANCER BIOLOGY & THERAPY

β-Carboline alkaloids bind DNA

(2010) Shohreh Nafisi et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Synthesis and antiviral activity of β-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1)

(2009) Anelise S. Nazari Formagio et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY