β-Carotene in the human body: metabolic bioactivation pathways – from digestion to tissue distribution and excretion
出版年份 2019 全文链接
标题
β-Carotene in the human body: metabolic bioactivation pathways – from digestion to tissue distribution and excretion
作者
关键词
-
出版物
PROCEEDINGS OF THE NUTRITION SOCIETY
Volume 78, Issue 1, Pages 68-87
出版商
Cambridge University Press (CUP)
发表日期
2019-02-12
DOI
10.1017/s0029665118002641
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- OUP accepted manuscript
- (2018) AMERICAN JOURNAL OF CLINICAL NUTRITION
- Retinoic Acid Increases Fatty Acid Oxidation and Irisin Expression in Skeletal Muscle Cells and Impacts Irisin In Vivo
- (2018) Jaume Amengual et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Magnesium affects spinach carotenoid bioaccessibility in vitro depending on intestinal bile and pancreatic enzyme concentrations
- (2018) Joana Corte-Real et al. FOOD CHEMISTRY
- Effect of processing on the bioaccessibility of bioactive compounds – A review focusing on carotenoids, minerals, ascorbic acid, tocopherols and polyphenols
- (2018) Antonio Cilla et al. JOURNAL OF FOOD COMPOSITION AND ANALYSIS
- In Vitro Micellarization and Intestinal Cell Uptake of cis Isomers of Lycopene Exceed Those of All-trans Lycopene
- (2018) Mark L. Failla et al. JOURNAL OF NUTRITION
- Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients
- (2018) Renata Lucas et al. Nutrients
- Reduced adiponectin expression after high-fat diet is associated with selective up-regulation of ALDH1A1 and further retinoic acid receptor signaling in adipose tissue
- (2017) Jean-Francois Landrier et al. FASEB JOURNAL
- Lipid digestion, micelle formation and carotenoid bioaccessibility kinetics: Influence of emulsion droplet size
- (2017) L. Salvia-Trujillo et al. FOOD CHEMISTRY
- Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans
- (2017) Torsten Bohn et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases
- (2017) Joseph L. Napoli PHARMACOLOGY & THERAPEUTICS
- RPE65 has an additional function as the lutein tomeso-zeaxanthin isomerase in the vertebrate eye
- (2017) Rajalekshmy Shyam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overview of carotenoid bioavailability determinants: From dietary factors to host genetic variations
- (2017) Charles Desmarchelier et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
- Are lutein, lycopene, and β-carotene lost through the digestive process?
- (2017) Rachel E. Kopec et al. Food & Function
- Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability
- (2017) Patrick Borel et al. Nutrients
- Common SNP rs6564851 in the BCO1 Gene Affects the Circulating Levels of β-Carotene and the Daily Intake of Carotenoids in Healthy Japanese Women
- (2017) Suemi Yabuta et al. PLoS One
- Eicosapentaenoic acid inhibits intestinal β-carotene absorption by downregulation of lipid transporter expression via PPAR-α dependent mechanism
- (2016) Purna Chandra Mashurabad et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Dietary calcium impairs tomato lycopene bioavailability in healthy humans
- (2016) Patrick Borel et al. BRITISH JOURNAL OF NUTRITION
- An Endogenous Mammalian Retinoid X Receptor Ligand, At Last!
- (2016) Ángel R. de Lera et al. ChemMedChem
- Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells
- (2016) Kosuke Takeda et al. DIABETES
- Molecular aspects of β, β-carotene-9′, 10′-oxygenase 2 in carotenoid metabolism and diseases
- (2016) Lei Wu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Carotenoid and polyphenol bioaccessibility and cellular uptake from plum and cabbage varieties
- (2016) Anouk Kaulmann et al. FOOD CHEMISTRY
- Stability and metabolism of Arbutus unedo bioactive compounds (phenolics and antioxidants) under in vitro digestion and colonic fermentation
- (2016) Juana I. Mosele et al. FOOD CHEMISTRY
- TSLP expression in the skin is mediated via RARγ-RXR pathways
- (2016) Johanna Mihály et al. IMMUNOBIOLOGY
- Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins
- (2016) Sara E. Thomas et al. JOURNAL OF LIPID RESEARCH
- Biomarkers of Dietary Intake Are Correlated with Corresponding Measures from Repeated Dietary Recalls and Food-Frequency Questionnaires in the Adventist Health Study-2
- (2016) Gary E Fraser et al. JOURNAL OF NUTRITION
- Molecular Basis for Vitamin A Uptake and Storage in Vertebrates
- (2016) Sylwia Chelstowska et al. Nutrients
- Consuming High-Carotenoid Fruit and Vegetables Influences Skin Yellowness and Plasma Carotenoids in Young Women: A Single-Blind Randomized Crossover Trial
- (2016) Kristine Pezdirc et al. Journal of the Academy of Nutrition and Dietetics
- Retinoic acid is abundantly detected in different depots of adipose tissue by SERS
- (2016) Jayakumar Perumal et al. Adipocyte
- Neonatal vitamin A supplementation associated with increased atopy in girls
- (2015) S. Aage et al. ALLERGY
- High provitamin A carotenoid serum concentrations, elevated retinyl esters, and saturated retinol-binding protein in Zambian preschool children are consistent with the presence of high liver vitamin A stores
- (2015) Stephanie Mondloch et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Tissue- and sex-specific effects of β-carotene 15,15′ oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice
- (2015) Youn-Kyung Kim et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Stability of bacterial carotenoids in the presence of iron in a model of the gastric compartment – Comparison with dietary reference carotenoids
- (2015) Charlotte Sy et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
- (2015) M. Luisa Bonet et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass
- (2015) Pierre-Jacques Brun et al. FASEB JOURNAL
- Mastication effects on carotenoid bioaccessibility from mango fruit tissue
- (2015) Dorrain Y. Low et al. FOOD RESEARCH INTERNATIONAL
- Carotenoids from fruits and vegetables: Chemistry, analysis, occurrence, bioavailability and biological activities
- (2015) Ramesh Kumar Saini et al. FOOD RESEARCH INTERNATIONAL
- Lycopene bioavailability is associated with a combination of genetic variants
- (2015) Patrick Borel et al. FREE RADICAL BIOLOGY AND MEDICINE
- All-transretinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes
- (2015) Franck Tourniaire et al. JOURNAL OF LIPID RESEARCH
- A Combination of Single-Nucleotide Polymorphisms Is Associated with Interindividual Variability in Dietary β-Carotene Bioavailability in Healthy Men
- (2015) Patrick Borel et al. JOURNAL OF NUTRITION
- Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors
- (2015) R. Rühl et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Dietary intake of carotenoids and risk of type 2 diabetes
- (2015) I. Sluijs et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Enterocyte fatty acid-binding proteins (FABPs): Different functions of liver and intestinal FABPs in the intestine
- (2015) Angela M. Gajda et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Relationship between Carotenoids, Retinol, and Estradiol Levels in Older Women
- (2015) Marcello Maggio et al. Nutrients
- 9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice
- (2015) Ralph Rühl et al. PLoS Genetics
- Interindividual variability of lutein bioavailability in healthy men: characterization, genetic variants involved, and relation with fasting plasma lutein concentration
- (2014) Patrick Borel et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Steroid concentrations in patients with atopic dermatitis: reduced plasma dehydroepiandrosterone sulfate and increased cortisone levels
- (2014) J. Mihály et al. BRITISH JOURNAL OF DERMATOLOGY
- Nuclear Receptors, RXR, and the Big Bang
- (2014) Ronald M. Evans et al. CELL
- In VitroModels for Studying Secondary Plant Metabolite Digestion and Bioaccessibility
- (2014) M. Alminger et al. COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
- The Human Enzyme That Converts Dietary Provitamin A Carotenoids to Vitamin A Is a Dioxygenase
- (2014) Carlo dela Seña et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dietary Carotenoids Are Associated with Cardiovascular Disease Risk Biomarkers Mediated by Serum Carotenoid Concentrations
- (2014) Ying Wang et al. JOURNAL OF NUTRITION
- Competitive regulation of human intestinal β-carotene 15,15′-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear factor (HNF)-1α and HNF-4α
- (2014) Noriaki Yamaguchi et al. LIFE SCIENCES
- Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention
- (2014) Anouk Kaulmann et al. NUTRITION RESEARCH
- Increased FADS2-Derived n-6 PUFAs and Reduced n-3 PUFAs in Plasma of Atopic Dermatitis Patients
- (2014) Johanna Mihály et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung
- (2014) Rosaria Piga et al. TOXICOLOGY
- β-Carotene regulates expression of β-carotene 15,15′-monoxygenase in human alveolar epithelial cells
- (2013) Xiaoming Gong et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- From fatty-acid sensing to chylomicron synthesis: Role of intestinal lipid-binding proteins
- (2013) Marjorie Buttet et al. BIOCHIMIE
- Dietary, anthropometric, and lifestyle correlates of serum carotenoids in postmenopausal women
- (2013) Agata Wawrzyniak et al. EUROPEAN JOURNAL OF NUTRITION
- Iron-induced oxidation of (all-E)-β-carotene under model gastric conditions: kinetics, products, and mechanism
- (2013) Charlotte Sy et al. FREE RADICAL BIOLOGY AND MEDICINE
- Non-Pro-Vitamin A and Pro-Vitamin A Carotenoids in Atopy Development
- (2013) R. Rühl INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Genetics and Diet Regulate Vitamin A Production via the Homeobox Transcription Factor ISX
- (2013) Glenn P. Lobo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism
- (2013) Jaume Amengual et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)
- (2013) Carlo dela Seña et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Retinol and retinyl esters: biochemistry and physiology
- (2013) Sheila M. O'Byrne et al. JOURNAL OF LIPID RESEARCH
- Carotenoid metabolism in mammals, including man: formation, occurrence, and function of apocarotenoids
- (2013) Abdulkerim Eroglu et al. JOURNAL OF LIPID RESEARCH
- CD36 and SR-BI Are Involved in Cellular Uptake of Provitamin A Carotenoids by Caco-2 and HEK Cells, and Some of Their Genetic Variants Are Associated with Plasma Concentrations of These Micronutrients in Humans
- (2013) Patrick Borel et al. JOURNAL OF NUTRITION
- Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin
- (2013) Janine Gericke et al. PLoS One
- Serum Carotenoids Reduce Progression of Early Atherosclerosis in the Carotid Artery Wall among Eastern Finnish Men
- (2013) Jouni Karppi et al. PLoS One
- Retinoid X receptors in macrophage biology
- (2013) Tamás Rőszer et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- β-Carotene 15,15′-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent
- (2012) Sara J Hendrickson et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis
- (2012) Weiya Jiang et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Stability and bioaccessibility of different forms of carotenoids and vitamin A during in vitro digestion
- (2012) Julie Courraud et al. FOOD CHEMISTRY
- Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein
- (2012) Jaume Amengual et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4)
- (2012) Philomena Alapatt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of physicochemical properties of carotenoids on their bioaccessibility, intestinal cell uptake, and blood and tissue concentrations
- (2012) Charlotte Sy et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina
- (2012) Joanna J Kaylor et al. Nature Chemical Biology
- Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids
- (2011) Earl H. Harrison BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Alcohol and aldehyde dehydrogenases: Retinoid metabolic effects in mouse knockout models
- (2011) Sandeep Kumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Retinyl ester hydrolases and their roles in vitamin A homeostasis
- (2011) Renate Schreiber et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives
- (2011) Hui Sun BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Analysis, occurrence, and function of 9-cis-retinoic acid
- (2011) Maureen A. Kane BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lipid metabolism in mammalian tissues and its control by retinoic acid
- (2011) M. Luisa Bonet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Physiological insights into all-trans-retinoic acid biosynthesis
- (2011) Joseph L. Napoli BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- An interaction between carotene-15,15′-monooxygenase expression and consumption of a tomato or lycopene-containing diet impacts serum and testicular testosterone
- (2011) Nikki A. Ford et al. INTERNATIONAL JOURNAL OF CANCER
- Contribution of violaxanthin, neoxanthin, phytoene and phytofluene to total carotenoid intake: Assessment in Luxembourg
- (2011) Eric Biehler et al. JOURNAL OF FOOD COMPOSITION AND ANALYSIS
- The Role of Dietary Fiber in the Bioaccessibility and Bioavailability of Fruit and Vegetable Antioxidants
- (2011) Hugo Palafox-Carlos et al. JOURNAL OF FOOD SCIENCE
- Divalent Minerals Decrease Micellarization and Uptake of Carotenoids and Digestion Products into Caco-2 Cells
- (2011) Eric Biehler et al. JOURNAL OF NUTRITION
- Single Nucleotide Polymorphisms Upstream from the β-Carotene 15,15'-Monoxygenase Gene Influence Provitamin A Conversion Efficiency in Female Volunteers
- (2011) Georg Lietz et al. JOURNAL OF NUTRITION
- Serum Retinoic Acid and Atopy Among Children of Different Ethnic Origin Living in Germany
- (2011) Christoph Grüber et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Gene expression response of mouse lung, liver and white adipose tissue to β-carotene supplementation, knockout of Bcmo1 and sex
- (2011) Yvonne G. J. van Helden et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Carotenoids and Their Isomers: Color Pigments in Fruits and Vegetables
- (2011) Hock-Eng Khoo et al. MOLECULES
- Beta-Carotene Reduces Body Adiposity of Mice via BCMO1
- (2011) Jaume Amengual et al. PLoS One
- Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes
- (2011) Emmanuelle Reboul et al. PROGRESS IN LIPID RESEARCH
- Vitamin A Metabolism: An Update
- (2011) Diana N. D’Ambrosio et al. Nutrients
- Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid
- (2010) Igor Shmarakov et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Molecular and dietary regulation of β,β-carotene 15,15′-monooxygenase 1 (BCMO1)
- (2010) Georg Lietz et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1−/− mice
- (2010) Yvonne G. J. van Helden et al. CARCINOGENESIS
- Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene
- (2010) Yvonne G. J. van Helden et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Beta-carotene affects gene expression in lungs of male and female Bcmo1 −/− mice in opposite directions
- (2010) Yvonne G. J. van Helden et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Retinol dehydrogenases (RDHs) in the visual cycle
- (2010) Ryan O. Parker et al. EXPERIMENTAL EYE RESEARCH
- ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β,β-carotene absorption and vitamin A production
- (2010) Glenn P. Lobo et al. FASEB JOURNAL
- A mitochondrial enzyme degrades carotenoids and protects against oxidative stress
- (2010) Jaume Amengual et al. FASEB JOURNAL
- Endogenous Ligands for Nuclear Receptors: Digging Deeper
- (2010) Michael Schupp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lecithin: retinol acyltransferase protein is distributed in both hepatic stellate cells and endothelial cells of normal rodent and human liver
- (2010) Keisuke Nagatsuma et al. LIVER INTERNATIONAL
- Retinoid X receptor gamma signaling accelerates CNS remyelination
- (2010) Jeffrey K Huang et al. NATURE NEUROSCIENCE
- Retinoyl β-Glucuronide: A Biologically Active Form of Vitamin A
- (2010) Arun B. Barua NUTRITION REVIEWS
- Serum carotenoids and atopy among children of different ethnic origin living in Germany
- (2010) Ralph Rühl et al. PEDIATRIC ALLERGY AND IMMUNOLOGY
- Common Variation in the β-Carotene 15,15′-Monooxygenase 1 Gene Affects Circulating Levels of Carotenoids: A Genome-wide Association Study
- (2009) Luigi Ferrucci et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The metabolism of triglyceride-rich lipoproteins revisited: New players, new insight
- (2009) Geesje M. Dallinga-Thie et al. ATHEROSCLEROSIS
- RPE65, Visual Cycle Retinol Isomerase, Is Not Inherently 11-cis-specific
- (2009) T. Michael Redmond et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver
- (2009) Renate Schreiber et al. JOURNAL OF LIPID RESEARCH
- Digestive Stability of Xanthophylls Exceeds That of Carotenes As Studied in a Dynamic in Vitro Gastrointestinal System
- (2009) Stéphanie Blanquet-Diot et al. JOURNAL OF NUTRITION
- In vitro and in vivo characterization of retinoid synthesis from β-carotene
- (2008) Yvette Fierce et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein
- (2008) Patrick Borel et al. BRITISH JOURNAL OF NUTRITION
- Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers
- (2008) W. C. Leung et al. FASEB JOURNAL
- Xanthophylls are preferentially taken up compared with β-carotene by retinal cells via a SRBI-dependent mechanism,
- (2008) Alexandrine During et al. JOURNAL OF LIPID RESEARCH
- Modulation of plasma all-trans retinoic acid concentrations by the consumption of carotenoid-rich vegetables
- (2008) Ralph Rühl et al. NUTRITION
- Retinoid receptor-activating ligands are produced within the mouse thymus during postnatal development
- (2007) Ildikó Kiss et al. EUROPEAN JOURNAL OF IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now