Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals

An ingestible bacterial-electronic system to monitor gastrointestinal health

(2018) Mark Mimee et al.   SCIENCE

Phosphatase activity tunes two-component system sensor detection threshold

(2018) Brian P. Landry et al.   Nature Communications

Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors

(2018) Ye Chen et al.   Nature Communications

Orthogonality and Burdens of Heterologous AND Gate Gene Circuits in E. coli

(2018) Qijun Liu et al.   ACS Synthetic Biology

Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention

(2018) Chun Loong Ho et al.   Nature Biomedical Engineering

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

(2017) David T Riglar et al.   NATURE BIOTECHNOLOGY

Remote detection of buried landmines using a bacterial sensor

(2017) Shimshon Belkin et al.   NATURE BIOTECHNOLOGY

A Microfluidic Biodisplay

(2017) Francesca Volpetti et al.   ACS Synthetic Biology

Development of a Pigment-Based Whole-Cell Zinc Biosensor for Human Serum

(2017) Daniel M. Watstein et al.   ACS Synthetic Biology

A Cell-Free Biosensor for Detecting Quorum Sensing Molecules in P. aeruginosa-Infected Respiratory Samples

(2017) Ke Yan Wen et al.   ACS Synthetic Biology

Development of SimCells as a novel chassis for functional biosensors

(2017) Cordelia P. N. Rampley et al.   Scientific Reports

Development of a highly specific and sensitive cadmium and lead microbial biosensor using synthetic CadC-T7 genetic circuitry

(2016) Hyun Ju Kim et al.   BIOSENSORS & BIOELECTRONICS

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

(2016) Keith Pardee et al.   CELL

Synchronous long-term oscillations in a synthetic gene circuit

(2016) Laurent Potvin-Trottier et al.   NATURE

Post-translational control of genetic circuits usingPotyvirusproteases

(2016) Jesus Fernandez-Rodriguez et al.   NUCLEIC ACIDS RESEARCH

Genetic circuit design automation

(2016) A. A. K. Nielsen et al.   SCIENCE

Amplification of small molecule-inducible gene expression via tuning of intracellular receptor densities

(2015) Baojun Wang et al.   NUCLEIC ACIDS RESEARCH

Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR

(2015) Chih-Chiang Chang et al.   NUCLEIC ACIDS RESEARCH

Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates

(2015) Alexis Courbet et al.   Science Translational Medicine

Regulatable and Modulable Background Expression Control in Prokaryotic Synthetic Circuits by Auxiliary Repressor Binding Sites

(2015) Davide Merulla et al.   ACS Synthetic Biology

Tunable protein degradation in bacteria

(2014) D Ewen Cameron et al.   NATURE BIOTECHNOLOGY

Biotechnological domestication of pseudomonads using synthetic biology

(2014) Pablo I. Nikel et al.   NATURE REVIEWS MICROBIOLOGY

Engineering modular and tunable genetic amplifiers for scaling transcriptional signals in cascaded gene networks

(2014) Baojun Wang et al.   NUCLEIC ACIDS RESEARCH

Design of orthogonal genetic switches based on a crosstalk map of  s, anti- s, and promoters

(2013) V. A. Rhodius et al.   Molecular Systems Biology

A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria

(2013) Nuria Quiles-Puchalt et al.   NUCLEIC ACIDS RESEARCH

Reprogramming Microbes to Be Pathogen-Seeking Killers

(2013) In Young Hwang et al.   ACS Synthetic Biology

Tuning Response Curves for Synthetic Biology

(2013) Jordan Ang et al.   ACS Synthetic Biology

A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals

(2012) Baojun Wang et al.   BIOSENSORS & BIOELECTRONICS

Four steps to avoid a synthetic-biology disaster

(2012) Genya V. Dana et al.   NATURE

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids

(2012) Fuzhong Zhang et al.   NATURE BIOTECHNOLOGY

Customizing cell signaling using engineered genetic logic circuits

(2012) Baojun Wang et al.   TRENDS IN MICROBIOLOGY

A pH-based biosensor for detection of arsenic in drinking water

(2011) K. de Mora et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Selective detection of gold using genetically engineered bacterial reporters

(2011) Sebastián Cerminati et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of a microfluidics biosensor for agarose-bead immobilized Escherichia coli bioreporter cells for arsenite detection in aqueous samples

(2011) Nina Buffi et al.   LAB ON A CHIP

A sensing array of radically coupled genetic ‘biopixels’

(2011) Arthur Prindle et al.   NATURE

Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology

(2011) Baojun Wang et al.   Nature Communications

Where microbiology meets microengineering: design and applications of reporter bacteria

(2010) Jan Roelof van der Meer et al.   NATURE REVIEWS MICROBIOLOGY

Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model

(2010) F. Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automated design of synthetic ribosome binding sites to control protein expression

(2009) Howard M Salis et al.   NATURE BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

A Stochastic Single-Molecule Event Triggers Phenotype Switching of a Bacterial Cell

(2008) P. J. Choi et al.   SCIENCE

Engineering BioBrick vectors from BioBrick parts

(2008) Reshma P Shetty et al.   Journal of Biological Engineering

Internal arsenite bioassay calibration using multiple bioreporter cell lines

(2007) Anke Wackwitz et al.   Microbial Biotechnology