标题
Antigen-specific therapeutic approaches for autoimmunity
作者
关键词
-
出版物
NATURE BIOTECHNOLOGY
Volume 37, Issue 3, Pages 238-251
出版商
Springer Nature
发表日期
2019-02-26
DOI
10.1038/s41587-019-0015-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells
- (2018) Leona Gabryšová et al. NATURE IMMUNOLOGY
- Effects of ATX-MS-1467 immunotherapy over 16 weeks in relapsing multiple sclerosis
- (2018) Jeremy Chataway et al. NEUROLOGY
- Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases
- (2018) Naru Zhang et al. VACCINE
- Lactococcus lactis As a Versatile Vehicle for Tolerogenic Immunotherapy
- (2018) Dana P. Cook et al. Frontiers in Immunology
- Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis
- (2018) Robert A. LaMothe et al. Frontiers in Immunology
- Autoreactive T cells in type 1 diabetes
- (2017) Alberto Pugliese JOURNAL OF CLINICAL INVESTIGATION
- Tolerogenic insulin peptide therapy precipitates type 1 diabetes
- (2017) Marie-Louise Bergman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Peptide–MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices
- (2017) Santiswarup Singha et al. Nature Nanotechnology
- Antigen-specific immunotherapies in rheumatic diseases
- (2017) Judit Pozsgay et al. Nature Reviews Rheumatology
- Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease
- (2017) Novalia Pishesha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type 1 diabetes induction in humanized mice
- (2017) Shulian Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
- (2017) Mohammad Alhadj Ali et al. Science Translational Medicine
- Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
- (2017) A. James M. Daveson et al. EBioMedicine
- Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
- (2016) G M Bell et al. ANNALS OF THE RHEUMATIC DISEASES
- Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells
- (2016) Tatiana Takiishi et al. DIABETES
- Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes
- (2016) Natalia Marek-Trzonkowska et al. Journal of Translational Medicine
- Expanding antigen-specific regulatory networks to treat autoimmunity
- (2016) Xavier Clemente-Casares et al. NATURE
- Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
- (2016) C. T. Ellebrecht et al. SCIENCE
- Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2
- (2016) Ada Yeste et al. Science Signaling
- Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2
- (2016) Ada Yeste et al. Science Signaling
- Thioreductase-Containing Epitopes Inhibit the Development of Type 1 Diabetes in the NOD Mouse Model
- (2016) Elin Malek Abrahimians et al. Frontiers in Immunology
- Tr1-Like T Cells – An Enigmatic Regulatory T Cell Lineage
- (2016) Anna Malgorzata White et al. Frontiers in Immunology
- Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes
- (2015) Ezio Bonifacio et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Intraperitoneal Administration of Autologous Tolerogenic Dendritic Cells for Refractory Crohn’s Disease: A Phase I Study
- (2015) Aranzazu Jauregui-Amezaga et al. Journal of Crohns & Colitis
- Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
- (2015) Antonella Carambia et al. JOURNAL OF HEPATOLOGY
- Use of Autoantigen-Loaded Phosphatidylserine-Liposomes to Arrest Autoimmunity in Type 1 Diabetes
- (2015) Irma Pujol-Autonell et al. PLoS One
- Adoptive cellular therapy: A race to the finish line
- (2015) Carl H. June et al. Science Translational Medicine
- Insulin B chain 9–23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3 + T regs
- (2015) Mahzad Akbarpour et al. Science Translational Medicine
- Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients
- (2015) Helen Benham et al. Science Translational Medicine
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens
- (2015) Alizée J. Grimm et al. Scientific Reports
- Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase
- (2015) K. M. Lorentz et al. Science Advances
- A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease
- (2014) Zoe Hunter et al. ACS Nano
- Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice
- (2014) S. Robert et al. DIABETES
- Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs
- (2014) Cezmi A. Akdis et al. JOURNAL OF CLINICAL INVESTIGATION
- Redirecting Therapeutic T Cells against Myelin-Specific T Lymphocytes Using a Humanized Myelin Basic Protein-HLA-DR2- Chimeric Receptor
- (2014) I. Moisini et al. JOURNAL OF IMMUNOLOGY
- Improved Efficacy of a Tolerizing DNA Vaccine for Reversal of Hyperglycemia through Enhancement of Gene Expression and Localization to Intracellular Sites
- (2014) N. Solvason et al. JOURNAL OF IMMUNOLOGY
- IL-10: The Master Regulator of Immunity to Infection
- (2014) Kevin N. Couper et al. JOURNAL OF IMMUNOLOGY
- Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance
- (2014) Roberto A. Maldonado et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy
- (2014) Bronwen R. Burton et al. Nature Communications
- GAD-treatment of children and adolescents with recent-onset type 1 diabetes preserves residual insulin secretion after 30 months
- (2013) Johnny Ludvigsson et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease
- (2013) Michael Bodd et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis
- (2013) Matthew S. Macauley et al. JOURNAL OF CLINICAL INVESTIGATION
- Dendritic Cell-Dependent In Vivo Generation of Autoregulatory T Cells by Antidiabetogenic MHC Class II
- (2013) S. Tsai et al. JOURNAL OF IMMUNOLOGY
- Engineered Regulatory T Cells Coexpressing MHC Class II:Peptide Complexes Are Efficient Inhibitors of Autoimmune T Cell Function and Prevent the Development of Autoimmune Arthritis
- (2013) Z. Qian et al. JOURNAL OF IMMUNOLOGY
- Exploiting Apoptosis for Therapeutic Tolerance Induction
- (2013) D. R. Getts et al. JOURNAL OF IMMUNOLOGY
- Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes
- (2013) B. O. Roep et al. Science Translational Medicine
- Antigen-Specific Tolerance by Autologous Myelin Peptide-Coupled Cells: A Phase 1 Trial in Multiple Sclerosis
- (2013) A. Lutterotti et al. Science Translational Medicine
- Transdermal Application of Myelin Peptides in Multiple Sclerosis Treatment
- (2013) Agata Walczak et al. JAMA Neurology
- Frequency of circulating autoreactive T cells committed to myelin determinants in relapsing–remitting multiple sclerosis patients
- (2012) Annie Elong Ngono et al. CLINICAL IMMUNOLOGY
- Stable antigen-specific T-cell hyporesponsiveness induced by tolerogenic dendritic cells from multiple sclerosis patients
- (2012) Dàlia Raϊch-Regué et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients With Refractory Crohn's Disease
- (2012) Pierre Desreumaux et al. GASTROENTEROLOGY
- Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading
- (2012) Suchitra Prasad et al. JOURNAL OF AUTOIMMUNITY
- Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice
- (2012) Tatiana Takiishi et al. JOURNAL OF CLINICAL INVESTIGATION
- PTPN22 Alters the Development of Regulatory T Cells in the Thymus
- (2012) C. J. Maine et al. JOURNAL OF IMMUNOLOGY
- CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
- (2012) Moa Fransson et al. Journal of Neuroinflammation
- Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
- (2012) Daniel R Getts et al. NATURE BIOTECHNOLOGY
- Increased Synapse Formation Obtained by T Cell Epitopes Containing a CxxC Motif in Flanking Residues Convert CD4+ T Cells into Cytolytic Effectors
- (2012) Vincent A. Carlier et al. PLoS One
- Engineering antigens for in situ erythrocyte binding induces T-cell deletion
- (2012) S. Kontos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2R null humanized mice
- (2011) E. Billerbeck et al. BLOOD
- Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients
- (2011) N. Giannoukakis et al. DIABETES CARE
- Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion
- (2011) James F. Mohan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tolerance Induced by Apoptotic Antigen-Coupled Leukocytes Is Induced by PD-L1+ and IL-10-Producing Splenic Macrophages and Maintained by T Regulatory Cells
- (2011) D. R. Getts et al. JOURNAL OF IMMUNOLOGY
- Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
- (2011) Diane K Wherrett et al. LANCET
- The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
- (2011) Yasutaka Motomura et al. NATURE IMMUNOLOGY
- A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS
- (2011) M. S. Freedman et al. NEUROLOGY
- Immune regulation of multiple sclerosis by transdermally applied myelin peptides
- (2010) Maciej Juryńczyk et al. ANNALS OF NEUROLOGY
- Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis
- (2010) R. A. Harry et al. ANNALS OF THE RHEUMATIC DISEASES
- Reversal of type 1 diabetes by a new MHC II-peptide chimera: “Single-epitope-mediated suppression” to stabilize a polyclonal autoimmune T-cell process
- (2010) Marvin Lin et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Antigenic strength controls the generation of antigen-specific IL-10-secreting T regulatory cells
- (2010) Leona Gabryšová et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Reversal of Autoimmunity by Boosting Memory-like Autoregulatory T Cells
- (2010) Sue Tsai et al. IMMUNITY
- Direct ex vivo analysis of allergen-specific CD4+ T cells
- (2010) William W. Kwok et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease
- (2010) J. A. Tye-Din et al. Science Translational Medicine
- Epitope-specific immunotherapy of rheumatoid arthritis: Clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial
- (2009) Eva C. Koffeman et al. ARTHRITIS AND RHEUMATISM
- No Effect of the Altered Peptide Ligand NBI-6024 on -Cell Residual Function and Insulin Needs in New-Onset Type 1 Diabetes
- (2009) M. Walter et al. DIABETES CARE
- Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10–secreting Th1 cells
- (2009) Leona Gabryšová et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Suppression of Ongoing T Cell-Mediated Autoimmunity by Peptide-MHC Class II Dimer Vaccination
- (2009) L. Li et al. JOURNAL OF IMMUNOLOGY
- Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes
- (2009) C. Capini et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells
- (2009) C. Pot et al. JOURNAL OF IMMUNOLOGY
- Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
- (2008) Hideki Garren et al. ANNALS OF NEUROLOGY
- Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
- (2008) Kirsti Näntö-Salonen et al. LANCET
- GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
- (2008) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
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