Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B

Lis1 dysfunction leads to traction force reduction and cytoskeletal disorganization during cell migration

(2018) Guo-Wei Jheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gli2 Rescues Delays in Brain Development Induced by Kif3a Dysfunction

(2018) Jia-Long Chen et al.   CEREBRAL CORTEX

Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

(2018) I-Ling Lu et al.   Nature Communications

COPI–TRAPPII activates Rab18 and regulates its lipid droplet association

(2016) Chunman Li et al.   EMBO JOURNAL

Acute accumulation of free cholesterol induces the degradation of perilipin 2 and Rab18-dependent fusion of ER and lipid droplets in cultured human hepatocytes

(2016) Asami Makino et al.   MOLECULAR BIOLOGY OF THE CELL

A mutation in the Warburg syndrome gene, RAB3GAP1, causes a similar syndrome with polyneuropathy and neuronal vacuolation in Black Russian Terrier dogs

(2016) Tendai Mhlanga-Mutangadura et al.   NEUROBIOLOGY OF DISEASE

PRRT2 mutations lead to neuronal dysfunction and neurodevelopmental defects

(2016) Yo-Tsen Liu et al.   Oncotarget

Identification of novel KIF11 mutations in patients with familial exudative vitreoretinopathy and a phenotypic analysis

(2016) Jia-Kai Li et al.   Scientific Reports

RAB18, a protein associated with Warburg Micro syndrome, controls neuronal migration in the developing cerebral cortex

(2016) Qinwei Wu et al.   Molecular Brain

ENU mutagenesis identifies mice modeling Warburg Micro Syndrome with sensory axon degeneration caused by a deletion in Rab18

(2015) Chih-Ya Cheng et al.   EXPERIMENTAL NEUROLOGY

Soybean isoflavone treatment induces osteoblast differentiation and proliferation by regulating analysis of Wnt/β-catenin pathway

(2015) Fang Yu et al.   GENE

Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation

(2015) Mark T. Handley et al.   Open Biology

Toward a Comprehensive Map of the Effectors of Rab GTPases

(2014) Alison K. Gillingham et al.   DEVELOPMENTAL CELL

A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton

(2014) S. M. Carpanini et al.   Disease Models & Mechanisms

Rab18 and a Rab18 GEF complex are required for normal ER structure

(2014) Andreas Gerondopoulos et al.   JOURNAL OF CELL BIOLOGY

Rab18 Facilitates Dengue Virus Infection by Targeting Fatty Acid Synthase to Sites of Viral Replication

(2014) W.-C. Tang et al.   JOURNAL OF VIROLOGY

Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid droplets

(2014) Hiromichi Dansako et al.   VIROLOGY

Autophagy-lysosome pathway associated neuropathology and axonal degeneration in the brains of alpha-galactosidase A-deficient mice

(2014) Michael P Nelson et al.   Acta Neuropathologica Communications

Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans

(2013) Ryan P. Liegel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutation Spectrum inRAB3GAP1,RAB3GAP2, andRAB18and Genotype-Phenotype Correlations in Warburg Micro Syndrome and Martsolf Syndrome

(2013) Mark T. Handley et al.   HUMAN MUTATION

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Rab and Arf Proteins in Genetic Diseases

(2013) Elsa Seixas et al.   TRAFFIC

Rab18 Binds to Hepatitis C Virus NS5A and Promotes Interaction between Sites of Viral Replication and Lipid Droplets

(2013) Shadi Salloum et al.   PLoS Pathogens

Molecular basis of Charcot–Marie–Tooth type 2B disease

(2012) Cecilia Bucci et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RAB3GAP1,RAB3GAP2andRAB18: disease genes in Micro and Martsolf syndromes

(2012) Mark T. Handley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Maturation of autophagosomes and endosomes: A key role for Rab7

(2012) Juha M.T. Hyttinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue

(2012) Marina R Pulido et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Loss-of-Function Mutations in RAB18 Cause Warburg Micro Syndrome

(2011) Danai Bem et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity

(2011) Marina R. Pulido et al.   PLoS One

Mutations in the Small GTPase Gene RAB39B Are Responsible for X-linked Mental Retardation Associated with Autism, Epilepsy, and Macrocephaly

(2010) Maila Giannandrea et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Visualization of the structures of the hepatitis C virus replication complex

(2010) Shih-Ching Chan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Canine inherited motor and sensory neuropathies: An updated classification in 22 breeds and comparison to Charcot–Marie–Tooth disease

(2010) Nicolas Granger   VETERINARY JOURNAL

The lysosome and neurodegenerative diseases

(2009) L. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Rab7 and the CMT2B disease

(2009) Laura Cogli et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Carpenter Syndrome

(2009) Pip Hidestrand et al.   JOURNAL OF CRANIOFACIAL SURGERY

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Rab18 and Rab43 have key roles in ER-Golgi trafficking

(2008) S. Y. Dejgaard et al.   JOURNAL OF CELL SCIENCE