Lymphatic endothelial cell calcium pulses are sensitive to spatial gradients in wall shear stress

GPR68 Senses Flow and Is Essential for Vascular Physiology

(2018) Jie Xu et al.   CELL

Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor

(2018) Xiangyu Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional outcomes and kinetic patterning of gene expression in response to NF-κB activation

(2018) Mingming Zhao et al.   PLOS BIOLOGY

DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12–CXCR4 signaling axis

(2017) Andrew H. Chang et al.   GENES & DEVELOPMENT

Laminar flow downregulates Notch activity to promote lymphatic sprouting

(2017) Dongwon Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves

(2016) Boksik Cha et al.   GENES & DEVELOPMENT

Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress

(2016) Vinay N. Surya et al.   Journal of the Royal Society Interface

Measurement of shear stress-mediated intracellular calcium dynamics in human dermal lymphatic endothelial cells

(2015) M. Jafarnejad et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of dynamic shear and transmural pressure on wall shear stress sensitivity in collecting lymphatic vessels

(2015) Jeffrey A. Kornuta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex

(2015) Brian G. Coon et al.   JOURNAL OF CELL BIOLOGY

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

(2015) Amélie Sabine et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph flow regulates collecting lymphatic vessel maturation in vivo

(2015) Daniel T. Sweet et al.   JOURNAL OF CLINICAL INVESTIGATION

Nanoscale Patterning of Extracellular Matrix Alters Endothelial Function under Shear Stress

(2015) Karina H. Nakayama et al.   NANO LETTERS

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

Endothelial Ca2+ oscillations reflect VEGFR signaling-regulated angiogenic capacity in vivo

(2015) Yasuhiro Yokota et al.   eLife

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

(2015) Nicolas Baeyens et al.   eLife

Microvascular Endothelial Cells Migrate Upstream and Align Against the Shear Stress Field Created by Impinging Flow

(2014) Maggie A. Ostrowski et al.   BIOPHYSICAL JOURNAL

Lymphatic collecting vessel maturation and valve morphogenesis

(2014) Daniel Vittet   MICROVASCULAR RESEARCH

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency decoding of calcium oscillations

(2013) Erik Smedler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanical forces in lymphatic vascular development and disease

(2013) Lara Planas-Paz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation

(2012) Amélie Sabine et al.   DEVELOPMENTAL CELL

Dynamic Response Diversity of NFAT Isoforms in Individual Living Cells

(2012) Nissan Yissachar et al.   MOLECULAR CELL

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

(2009) Eleni Bazigou et al.   DEVELOPMENTAL CELL

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

NFATc1 regulates lymphatic endothelial development

(2009) Rishikesh M. Kulkarni et al.   MECHANISMS OF DEVELOPMENT

Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

(2008) Surya M. Nauli et al.   CIRCULATION