标题
The relevance of persisters in tuberculosis drug discovery
作者
关键词
-
出版物
MICROBIOLOGY-SGM
Volume -, Issue -, Pages -
出版商
Microbiology Society
发表日期
2019-02-18
DOI
10.1099/mic.0.000760
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stochastic expression of lactate dehydrogenase A induces Escherichia coli persister formation
- (2018) Naoki Yamamoto et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Microbe Profile: Mycobacterium tuberculosis: Humanity's deadly microbial foe
- (2018) Stephen V. Gordon et al. MICROBIOLOGY-SGM
- Viability, biofilm formation, and MazEF expression in drug-sensitive and drug-resistant Mycobacterium tuberculosis strains circulating in Xinjiang, China
- (2018) Jili Zhao et al. Infection and Drug Resistance
- Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria
- (2018) Alexandra Sakatos et al. Science Advances
- Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle mycobacterial adaptation
- (2018) Amar Deep et al. NUCLEIC ACIDS RESEARCH
- Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity
- (2017) E. Hesper Rego et al. NATURE
- Persistent bacterial infections and persister cells
- (2017) Robert A. Fisher et al. NATURE REVIEWS MICROBIOLOGY
- Enhanced respiration prevents drug tolerance and drug resistance inMycobacterium tuberculosis
- (2017) Catherine Vilchèze et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mycobacterium tuberculosis PhoY Proteins Promote Persister Formation by Mediating Pst/SenX3-RegX3 Phosphate Sensing
- (2017) Sarah B. Namugenyi et al. mBio
- Mycobacterium smegmatis PhoU Proteins Have Overlapping Functions in Phosphate Signaling and Are Essential
- (2017) Alyssa M. Brokaw et al. Frontiers in Microbiology
- Identification of drug candidates that enhance pyrazinamide activity from a clinical compound library
- (2017) Hongxia Niu et al. Emerging Microbes & Infections
- Mycobacterium tuberculosis Is Selectively Killed by Rifampin and Rifapentine in Hypoxia at Neutral pH
- (2016) Angelo Iacobino et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro
- (2016) Jees Sebastian et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors
- (2016) Ganesh Samala et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Potential of immunomodulatory agents as adjunct host-directed therapies for multidrug-resistant tuberculosis
- (2016) Alimuddin Zumla et al. BMC Medicine
- Molecular mechanisms and clinical implications of bacterial persistence
- (2016) Joran Elie Michiels et al. DRUG RESISTANCE UPDATES
- Mycobacterium tuberculosis can gain access to adipose depots of mice infected via the intra-nasal route and to lungs of mice with an infected subcutaneous fat implant
- (2016) Pooja Agarwal et al. MICROBIAL PATHOGENESIS
- Elucidating population-wide mycobacterial replication dynamics at the single-cell level
- (2016) Jacoba M. Mouton et al. MICROBIOLOGY-SGM
- High Persister Mutants in Mycobacterium tuberculosis
- (2016) Heather L. Torrey et al. PLoS One
- Mechanisms of bacterial persistence during stress and antibiotic exposure
- (2016) Alexander Harms et al. SCIENCE
- Defining dormancy in mycobacterial disease
- (2016) S. Lipworth et al. TUBERCULOSIS
- Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis
- (2015) Ben Gold et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Uncoupling Environmental pH and Intrabacterial Acidification from Pyrazinamide Susceptibility in Mycobacterium tuberculosis
- (2015) Nicholas D. Peterson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of potential Mycobacterium tuberculosis topoisomerase I inhibitors: A study against active, dormant and resistant tuberculosis
- (2015) Jonnalagadda Padma Sridevi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Activity of lipophilic and hydrophilic drugs against dormant and replicating Mycobacterium tuberculosis
- (2015) Giovanni Piccaro et al. JOURNAL OF ANTIBIOTICS
- The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition
- (2015) Shaleen B. Korch et al. JOURNAL OF MICROBIOLOGY
- Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis
- (2015) Yu-Min Chuang et al. mBio
- Erratum: Corrigendum: MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs
- (2015) Prabhakar Tiwari et al. Nature Communications
- In VitroandIn VivoActivities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis
- (2014) Ming Zhang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Development of novel tetrahydrothieno[2,3-c]pyridine-3-carboxamide based Mycobacterium tuberculosis pantothenate synthetase inhibitors: Molecular hybridization from known antimycobacterial leads
- (2014) Ganesh Samala et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Mycobacterium tuberculosis persistence in various adipose depots of infected mice and the effect of anti-tubercular therapy
- (2014) Pooja Agarwal et al. MICROBES AND INFECTION
- How sisters grow apart: mycobacterial growth and division
- (2014) Karen J. Kieser et al. NATURE REVIEWS MICROBIOLOGY
- A Trial of Mass Isoniazid Preventive Therapy for Tuberculosis Control
- (2014) Gavin J. Churchyard et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis
- (2014) Corinne S. Merle et al. NEW ENGLAND JOURNAL OF MEDICINE
- Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis
- (2014) Stephen H. Gillespie et al. NEW ENGLAND JOURNAL OF MEDICINE
- High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis
- (2014) Amina Jindani et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
- (2014) B. Javid et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bacterial persisters: formation, eradication, and experimental systems
- (2014) Sophie Helaine et al. TRENDS IN MICROBIOLOGY
- Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis
- (2014) Ambre Sala et al. Toxins
- Persisters, persistent infections and the Yin–Yang model
- (2014) Ying Zhang Emerging Microbes & Infections
- Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model
- (2013) Sarah Schmidt Grant et al. ACS Chemical Biology
- Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosis
- (2013) Jansy Sarathy et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Activities of Drug Combinations against Mycobacterium tuberculosis Grown in Aerobic and Hypoxic Acidic Conditions
- (2013) Giovanni Piccaro et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Microbial Persistence and the Road to Drug Resistance
- (2013) Nadia R. Cohen et al. Cell Host & Microbe
- Persister populations of Mycobacterium tuberculosis in sputum that grow in liquid but not on solid culture media
- (2013) J. Dhillon et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Detection of inhibitors of phenotypically drug-tolerant Mycobacterium tuberculosis using an in vitro bactericidal screen
- (2013) Ian M. Bassett et al. JOURNAL OF MICROBIOLOGY
- Activated ClpP kills persisters and eradicates a chronic biofilm infection
- (2013) B. P. Conlon et al. NATURE
- Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis
- (2013) Crystal M. Darby et al. PLoS One
- Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
- (2013) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
- (2013) R. A. Fasani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic Persistence of Antibiotic-Stressed Mycobacteria
- (2013) Y. Wakamoto et al. SCIENCE
- Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction
- (2013) Catherine Vilchèze et al. Nature Communications
- Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis
- (2012) Pravin S. Shirude et al. ACS Chemical Biology
- A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis
- (2012) Puiying A. Mak et al. ACS Chemical Biology
- Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis
- (2012) Ian M. Rosenthal et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Targeting Persisters for Tuberculosis Control
- (2012) Ying Zhang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Successful Shortening of Tuberculosis Treatment Using Adjuvant Host-Directed Therapy with FDA-Approved Phosphodiesterase Inhibitors in the Mouse Model
- (2012) Mamoudou Maiga et al. PLoS One
- Large mutational target size for rapid emergence of bacterial persistence
- (2012) H. S. Girgis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals
- (2012) Sarah Schmidt Grant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis
- (2011) Ruth J. Napier et al. Cell Host & Microbe
- Heterogeneous bacterial persisters and engineering approaches to eliminate them
- (2011) Kyle R Allison et al. CURRENT OPINION IN MICROBIOLOGY
- Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies
- (2011) M. Fauvart et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Bacterial persistence by RNA endonucleases
- (2011) Etienne Maisonneuve et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dormant ovoid cells of Mycobacterium tuberculosis are formed in response to gradual external acidification
- (2011) Margarita O. Shleeva et al. TUBERCULOSIS
- Persister Cells
- (2010) Kim Lewis Annual Review of Microbiology
- Activity of Drug Combinations against Dormant Mycobacterium tuberculosis
- (2010) P. Filippini et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Delineation of a Bacterial Starvation Stress Response Network Which Can Mediate Antibiotic Tolerance Development
- (2010) D. K. C. Fung et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- PhoY2 but not PhoY1 is the PhoU homologue involved in persisters in Mycobacterium tuberculosis
- (2010) W. Shi et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The Frequency of Persisters in Escherichia coli Reflects the Kinetics of Awakening from Dormancy
- (2010) A. Joers et al. JOURNAL OF BACTERIOLOGY
- Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli
- (2010) Tobias Dörr et al. PLOS BIOLOGY
- Novel persistence genes inPseudomonas aeruginosaidentified by high-throughput screening
- (2009) Valerie N. De Groote et al. FEMS MICROBIOLOGY LETTERS
- Energy production genessucBandubiFâ are involved in persister survival and tolerance to multiple antibiotics and stresses inEscherichia coli
- (2009) Chao Ma et al. FEMS MICROBIOLOGY LETTERS
- Stress-Induced -Lactam Antibiotic Resistance Mutation and Sequences of Stationary-Phase Mutations in the Escherichia coli Chromosome
- (2009) J. F. Petrosino et al. JOURNAL OF BACTERIOLOGY
- Discovery of Novel Proteasome Inhibitors Using a High-Content Cell-Based Screening System
- (2009) Irena Lavelin et al. PLoS One
- SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli
- (2009) Tobias Dörr et al. PLoS Genetics
- Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution
- (2009) Holly R. Ramage et al. PLoS Genetics
- Selective Killing of Nonreplicating Mycobacteria
- (2008) Ruslana Bryk et al. Cell Host & Microbe
- In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide
- (2008) R. Villar et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum
- (2008) Natalie J Garton et al. PLOS MEDICINE
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