Article
Infectious Diseases
Juana Liz Leslie Cucho-Medrano, Sammy Wesley Mendoza-Beingolea, Cesar Maximo Fuertes-Ruiton, Maria Elena Salazar-Salvatierra, Oscar Herrera-Calderon
Summary: The study aimed at determining the volatile phytochemical constituents in the essential oils of Croton species leaves and evaluating their antimicrobial activity. The oils showed in vitro antimicrobial activity against bacterial or fungal strains.
Article
Nanoscience & Nanotechnology
Zenon Toprakcioglu, Elizabeth G. Wiita, Akhila K. Jayaram, Rebecca C. Gregory, Tuomas P. J. Knowles
Summary: The emergence of drug-resistant bacteria and fungi is a global concern in healthcare. Developing effective small molecule therapeutic strategies is challenging, thus, exploring biomaterials with physical modes of action is an alternative approach. In this study, silk-based films embedded with selenium nanoparticles were found to exhibit antibacterial and antifungal properties while remaining biocompatible and noncytotoxic towards mammalian cells.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Infectious Diseases
Priscilla Augusta de Sousa Fernandes, Josefa Carolaine Pereira da Silva, Debora Lima Sales, Paulo Riceli Vasconcelos Ribeiro, Edy Sousa de Brito, Marta Regina Kerntopf, Gyllyandeson de Araujo Delmondes, Jacqueline Cosmo Andrade Pinheiro, Gerson Javier Torres Salazar, Francisco Lucas Alves Batista, Francisco Ernani Alves Magalhaes, Maria Celeste Vega Gomez, Miriam Rolon, Cathia Coronel, Jaime Ribeiro-Filho, Jose Weverton Almeida-Bezerra, Abolghasem Siyadatpanah, Veeranoot Nissapatorn, Maria de Lourdes Pereira, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga
Summary: The study investigated the chemical composition and pharmacological potential of an aqueous extract obtained from the roots of Croton heliotropiifolius, revealing its antioxidant and antifungal effects, as well as its ability to enhance the effectiveness of fluconazole. However, it showed weak antiparasitic effects.
Article
Chemistry, Medicinal
Suvi T. Hakkinen, Marina Sokovic, Liisa Nohynek, Ana Ciric, Marija Ivanov, Dejan Stojkovic, Irina Tsitko, Melanie Matos, Joao P. Baixinho, Viktoriya Ivasiv, Naiara Fernandez, Claudia Nunes dos Santos, Kirsi-Marja Oksman-Caldentey
Summary: Chicory contains bioactive compounds with antimicrobial, antifungal, and antibiofilm activities. Supercritical fluid extracts showed the highest bioactivity, inhibiting drug-resistant bacteria and fungi. There is potential for the development of novel antibacterial and antifungal preparations from chicory extracts.
Article
Materials Science, Multidisciplinary
Mohammad Hegazy
Summary: Thermo-responsive nanocontainers were synthesized by modifying mesoporous silica nanoparticles (MSN) with two copolymers, PMPS and PVCL. The loading and release of the antifungal drug AFG were controlled by the temperature-responsive PVCL, and the nanocontainers exhibited a killing effect against four strains of fungi. These stimuli-sensitive nanocontainers have great potential for biomedical applications.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Luis Enrique Garcia-Marin, Karla Juarez-Moreno, Alfredo Rafael Vilchis-Nestor, Ernestina Castro-Longoria
Summary: The biosynthesized copper oxide nanoparticles exhibit significant inhibitory effect on Candida albicans, showing potential as a candidate for developing topical antifungal treatment. Analysis reveals that exposure to nanoparticles leads to production of reactive oxygen species (ROS) in C. albicans, with nanoparticles distributed both inside and outside the cells, having minimal impact on cell viability.
Article
Plant Sciences
Shiqin Jiang, Xiuting Shen, Shenxin Xuan, Bao Yang, Qingfeng Ruan, Hui Cui, Zhongxiang Zhao, Jing Jin
Summary: Croton crassifolius Geisel (CCG) extract has shown therapeutic potential against ulcerative colitis (UC) by modulating metabolic pathways and reducing inflammation, offering a new strategy for UC management.
Article
Chemistry, Physical
Jing Zhang, Haoning Gong, Mingrui Liao, Zongyi Li, Ralf Schweins, Jeffrey Penny, Jian R. Lu
Summary: The research designed a group of short AMPs with high antifungal activities against Candida species and Cryptococcus neoformans, some of which showed effectiveness against fungal biofilms with low cytotoxicity to host cells. The fast action and high selectivity of these AMPs were found to be correlated to their fast membrane lysis, evidenced by various measurements and simulations.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Immunology
Rewan Abdelaziz, Yasmine H. Tartor, Ahmed B. Barakat, Gamal EL-Didamony, Marwa M. Gado, Adina Berbecea, Habil Dr. Isidora Radulov
Summary: This study aimed to discover a broad-spectrum biomaterial for treating multidrug-resistant bacterial and fungal infections. Streptomyces species were isolated from soil samples, and the most active strains with antimicrobial activity were identified. The bioactive metabolites extracted from these strains showed significant inhibitory effects against MDR bacteria and fungi, and demonstrated therapeutic efficacy in mouse models.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Polymer Science
Rana A. A. Alharbi, Fahad M. M. Alminderej, Nouf F. F. Al-Harby, Noura Y. Y. Elmehbad, Nadia A. A. Mohamed
Summary: A new series of hydrogels were prepared by incorporating substituted bisuracil linkages between chitosan Schiff's base chains and between chitosan chains. The structure of the hydrogels was confirmed through various techniques. The inhibitory effects of the hydrogels against different microbes were studied, with ZnO nanoparticle composites showing the highest inhibition potency.
Article
Food Science & Technology
Marie-Louise Heymich, Laura Nissl, Dominik Hahn, Matthias Noll, Monika Pischetsrieder
Summary: The study found that antimicrobial peptides Leg1 and Leg2 from chickpea have the potential to be used as preservatives against bacterial, fungal, and oxidative spoilage in food and other products, without cytotoxic effects on human cells. Additionally, Leg2 showed antioxidative activity by radical scavenging and reducing mechanisms.
Article
Materials Science, Multidisciplinary
C. M. Lopez-Badillo, M. Hernandez-Gonzalez, F. Hernandez-Centeno, I. Olivas-Armendariz, C. A. Rodriguez-Gonzalez, E. M. Muzquiz-Ramos, J. Lopez-Cuevas, H. Y. Lopez-De la Pena
Summary: CaO nanoparticles doped with different concentrations of Ag were synthesized by the sol-gel method to enhance their antimicrobial activity. The cytotoxicity study showed a cell viability percentage above 70%, indicating the nanoparticles could be used in medical and food applications.
Article
Chemistry, Multidisciplinary
Dmitry Korolev, Michael Shumilo, Galina Shulmeyster, Alexander Krutikov, Alexey Golovkin, Alexander Mishanin, Andrew Gorshkov, Anna Spiridonova, Anna Domorad, Alexander Krasichkov, Michael Galagudza
Summary: This study aimed to develop a technique for colloidal silver nanoparticle (AgNP) modification to increase stability in aqueous suspensions, reduce cytotoxicity, and enhance antimicrobial effects. Results showed that albumin coating significantly improved stability, decreased cytotoxicity, and conferred potent antimicrobial action, with Tween-80 modification demonstrating significant hemolysis and dose-dependent cytotoxic effects.
Article
Pharmacology & Pharmacy
Blanca de Juan Mora, Luis Filipe, Andreia Forte, Miguel M. Santos, Celso Alves, Fernando Teodoro, Rui Pedrosa, Manuela Ribeiro Carrott, Luis C. Branco, Sandra Gago
Summary: In this study, two nanomaterials based on mesoporous silica nanoparticles immobilized with ciprofloxacin were prepared and characterized for their structures and antimicrobial activities. The nanomaterials showed promising antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, and Klebsiella pneumoniae, with higher activity than the precursor and neutral ciprofloxacin.
Article
Biochemistry & Molecular Biology
Davide Campoccia, Lucio Montanaro, Stefano Ravaioli, Valentina Mariani, Giulia Bottau, Andrea De Donno, Carla Renata Arciola
Summary: In orthopedic surgery, preventing biomaterial-associated infections is a major concern. An effective strategy is to use anti-infective biomaterials that are coated, grafted, or doped with alternative molecules to conventional antibiotics. Antimicrobial peptides (AMPs) show promise as candidate molecules for this purpose. This study explored the potential of the peptide Dadapin-1, finding it to have significant antibacterial properties against relevant bacterial species while being non-cytotoxic to human cells. These findings suggest Dadapin-1 could be used in the production of anti-infective biomaterials.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.