Article
Environmental Sciences
Mathan Ramesh, Madhavan Sujitha, Pottanthara Ashokan Anila, Zongming Ren, Rama Krishnan Poopal
Summary: Ciprofloxacin, a widely used antibiotic, has been found to have ecological toxicity on Cirrhinus mrigala, leading to imbalanced oxidative defense system, tissue structural changes, and decreased plasma inorganic ion levels. These findings could serve as reliable biomarkers for antibiotic toxicity studies and may provide insights into the potential molecular impacts and adverse effects of ciprofloxacin on aquatic organisms.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Physiology
Elizabeth DiBona, Lee J. Pinnell, Annika Heising-Huang, Simon Geist, Jeffrey W. Turner, Frauke Seemann
Summary: Microplastic pollution is a global concern for environmental health, aquaculture, and fisheries. Studies have shown that microplastic ingestion may impact fish health, specifically causing intestinal damage and microbiota imbalances. Although no imminent threat to fish health was found at current environmental levels of microplastics, close monitoring of important spawning grounds is recommended.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Environmental Sciences
Yuyan Zhong, Jing Ren, Rui Li, Yuxin Xuan, Wu Yao, Qianye Yang, Yin Gan, Shuling Yu, Jintao Yuan
Summary: This study predicted the binding probability of 44 fluorinated biphenyls and their analogues (FBAs) to different nuclear hormone receptors (NHRs) using an endocrine-disrupting activity prediction tool. Molecular similarity and network toxicology analysis were used to enhance the screening process. The results revealed that FBAs have high binding potential for various NHRs, and the degree of receptor overlap was related to the Tanimoto coefficient of FBAs. Network toxicology analysis verified some of the docking screening results and identified important endocrine-disrupting pathways. This study identified potential endocrine-disrupting FBAs and developed a workflow for prioritizing the risk of potential endocrine-disrupting compounds using in silico approaches.
Article
Environmental Sciences
Anja Erasmus, Nico J. Smit, Sonja Zimmermann, Milen Nachev, Bernd Sures, Victor Wepener
Summary: Analysis of Clinus superciliosus along the South African coast revealed that element concentrations were influenced by oceanographic processes and seasonal geological run-off, with no significant correlation found between size and sex with element concentrations. Limited data highlights the need for further studies on element accumulation in intertidal fish species in South Africa.
MARINE POLLUTION BULLETIN
(2021)
Article
Environmental Sciences
Hui Liu, Yanyan Xu, Yuming Wang, Chunyang Liu, Jun Chen, Simiao Fan, Lijuan Xie, Yaqian Dong, Siyu Chen, Wenjie Zhou, Yubo Li
Summary: This study investigated the effects of paclobutrazol and uniconazole on the thyroid endocrine system in rats. Biomarkers of thyroid endocrine disruption induced by these chemicals were identified using lipidomic analysis. Network pharmacology was utilized to discover potential targets related to the biomarkers. The results showed that both paclobutrazol and uniconazole caused thyroid endocrine disorders in male and female rats, with stronger effects observed in females.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Odera Chukwumaijem Okafor, Williams Onwe Obaze, Chima Njoku, Sandra Chisom Udenze
Summary: This study investigates the impact of waste disposal sites on the physicochemical properties of water in selected states of Southeast Nigeria. The results show that during the wet season, values of BOD, COD, and other indicators were higher compared to the dry season and the respective controls. The study recommends proper awareness to prevent contamination of surface water bodies near waste disposal sites.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2023)
Article
Biochemistry & Molecular Biology
Vesela Yancheva, Elenka Georgieva, Iliana Velcheva, Ilia Iliev, Stela Stoyanova, Tonka Vasileva, Veselin Bivolarski, Dobrinka Todorova-Bambaldokova, Nurfatin Zulkipli, Laszlo Antal, Krisztian Nyeste
Summary: This study evaluated the toxicity of chlorpyrifos (CPF) and cypermethrin (CYP) on common carp, and found that CYP had a more prominent effect on fish organs, biochemical responses, behavior, and respiration rate compared to CPF. The results also indicated that the liver is more susceptible to chronic and chemically induced cellular stress compared to the gills.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Marine & Freshwater Biology
S. Bony, M. Labeille, E. Lefrancois, P. Noury, J. M. Olivier, R. Santos, N. Teichert, A. Besnard, A. Devaux
Summary: Implementing the European Water Framework Directive in tropical areas like the French West Indies (FWI) requires the selection of relevant aquatic sentinel species to investigate the ecological status of surface waters. This study focuses on the biological response of the widespread fish Sicydium spp. in Guadeloupe island, using enzymatic biomarkers and genotoxicity endpoints to assess river chemical quality. The results show significant differences in hepatic EROD activity, micronucleus frequency, and DNA damage level between fish from the most contaminated and low contaminated rivers, suggesting the usefulness of Sicydium spp. as sentinel species in assessing river quality and chemical pressures in FWI.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Limin Wang, Shengxuan Li, Ibrahim M. Ahmad, Guiying Zhang, Yanfeng Sun, Yang Wang, Congnan Sun, Chuan Jiang, Peng Cui, Dongming Li
Summary: Face masks are essential in preventing the transmission of viruses, but their increased production and use during the COVID-19 pandemic have led to global ecological challenges, such as resource consumption and environmental pollution. This review examines the environmental impacts of face masks, including energy consumption, waste disposal and pollution. Countermeasures, such as increasing public awareness and developing biodegradable masks, are proposed to mitigate these ecological crises.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Si-jie Jiang, Jingchun Sun, Gongsong Tong, Hao Ding, Jiewei Ouyang, Qiang Zhou, Yunxiang Fu, Mei-E Zhong
Summary: Phytoextraction is an effective method for remediation of heavy metal contaminated soil, with increasing focus on the harmless disposal and value-added use of harmful phytoextraction biomass (HPB). Various disposal technologies for HPB have been studied, such as composting and enzyme hydrolysis. In the future, the phytoextraction process should be combined with the disposal of HPB, and a grading handling strategy is suggested.
Article
Multidisciplinary Sciences
Shahid Mahboob, Zubair Ahmed, H. F. Alkahem Al-Balawi, Khalid A. Al-Ghanim, Promy Virik, N. Al-Mulham, F. Al-Misned
Summary: This research aims to investigate genotoxicity in fish and screen the aquatic ecosystem. The study found that Epinephalus chlorostigma showed the highest sensitivity to pollution, with high frequencies of DNA fragmentation, micronucleus induction, and nuclear abnormalities. The study suggests that this fish species and novel DNA damage assays can be effective tools for toxicity screening and water body monitoring.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Energy & Fuels
Anderson Anderson, Rameshkumar Chandralingam, T. R. PraveenKumar
Summary: This paper discusses the importance of plastics in daily life and the environmental impacts of plastic consumption during COVID-19. Plastics play a crucial role in the medical industry, but improper management can exacerbate infection rates and lead to worsening plastic pollution on a global scale.
ENERGY SOURCES PART A-RECOVERY UTILIZATION AND ENVIRONMENTAL EFFECTS
(2021)
Article
Engineering, Geological
Brendan C. O'Kelly, Abbas El-Zein, Xiaoli Liu, Anjan Patel, Xunchang Fei, Susmita Sharma, Arif Mohammad, Venkata Siva Naga Sai Goli, Jing Jing Wang, Dunzhu Li, Yunhong Shi, Liwen Xiao, Ganaraj Kuntikana, Bettadapura Subramanyam Shashank, Theo S. Sarris, Bendadi Hanumantha Rao, Abdel Mohsen O. Mohamed, Evan K. Paleologos, Mohaddeseh Mousavi Nezhad, Devendra N. Singh
Summary: Microplastics (MPs) are persistent contaminants in the terrestrial subsurface with significant effects on soil biological and ecosystem functions. Research has focused on the accumulation, fate, and effects of MPs in soil, as well as mitigation measures such as using MP-eating soil bacteria and fungi. Additionally, studies have explored the combined effects of MPs and other environmental contaminants, along with standardization of detection methods for MPs in soils.
ENVIRONMENTAL GEOTECHNICS
(2021)
Article
Pharmacology & Pharmacy
Gobichettipalayam Balasubramaniam Maadurshni, Manigandan Nagarajan, Saravanan Priyadharshini, Usha Singaravelu, Jeganathan Manivannan
Summary: This study explores the adverse outcome pathways of 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene (MBP), the main active metabolite of bisphenol A (BPA), as a potential health risk of plastic derived chemicals. Computational analysis reveals that MBP may target various physiological signaling pathways (MAPK and VEGF related angiogenesis signaling) and disease progression pathways (hypertension, cancer, and endocrine disorders). Validation studies support the impacts of MBP on cardiovascular pathogenesis. These findings provide novel insights for future health risk assessment of plastic derived chemicals.
Review
Engineering, Environmental
Alice K. M. Morita, Carolina Ibelli-Bianco, Jamil A. A. Anache, Jaqueline Coutinho, Natalia S. Pelinson, Juliana Nobrega, Livia M. P. Rosalem, Camila M. C. Leite, Leonardo M. Niviadonski, Caroline Manastella, Edson Wendland
Summary: This work provides an overview of environmental studies conducted in areas affected by dumpsites and nonsanitary landfills in Brazil, identifying main contaminants and assessing their environmental impact for guidance on intervention measures. The results reveal that Brazilian dumpsites are causing negative impacts on surrounding soils and water resources, posing ecological and public health risks that persist even after closure. Additionally, the study suggests the need for strict enforcement methods and monitoring plans to address this significant environmental problem in Brazil.
Article
Multidisciplinary Sciences
Silje Modahl Johanson, Erik Ropstad, Gunn Charlotte Ostby, Mona Aleksandersen, Galia Zamaratskaia, Gudrun Seeberg Boge, Ruth Halsne, Cathrine Trangerud, Jan Ludvig Lyche, Hanne Friis Berntsen, Karin Elisabeth Zimmer, Steven Verhaegen
Summary: This study found that in utero and lactational exposure to persistent organic pollutants had significant effects on female offspring in terms of mammary gland development, ovarian follicle maturation, and liver function, indicating potential harm to the female reproductive system and liver function from persistent organic pollutants.
Article
Environmental Sciences
Ane Haarr, Eliezer B. Mwakalapa, Aviti J. Mmochi, Jan L. Lyche, Anders Ruus, Halima Othman, Martin M. Larsen, Katrine Borga
Summary: Seasonal differences in precipitation may affect contaminant dynamics in tropical coastal regions, with higher concentrations of organohalogen contaminants found in marine organisms collected after the rainy season compared to before, indicating the impact of seasonal rainfall on contaminant distribution in coastal ecosystems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Applied
Chalumba Kachusi Simukoko, Eliezer Brown Mwakalapa, Patricia Bwalya, Kaampwe Muzandu, Vidar Berg, Stephen Mutoloki, Anuschka Polder, Jan Ludvig Lyche
Summary: The study found that levels of essential metals were higher in farmed tilapia, while levels of non-essential metals were higher in wild tilapia. Wild fish near the fish farms had significantly higher levels of essential metals compared to those distant from the farms. The estimated weekly intake for all metals was below the provisional tolerable weekly intakes.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2022)
Article
Clinical Neurology
Gerd Haga Bringeland, Nello Blaser, Kjell-Morten Myhr, Christian Alexander Vedeler, Sonia Gavasso
Summary: The study found that extending the dosing interval of natalizumab from 4 to 6 weeks resulted in 50% of patients reporting new or increased wearing-off symptoms, with those with pre-existing symptoms experiencing a higher frequency of symptom increase. These observations advocate for further research on the effect of extended interval dosing on wearing-off symptoms in randomized controlled trials.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Neurosciences
Ajay Yadav, Steven Verhaegen, Mussie Ghezu Hadera, Hanne Friis Berntsen, Vidar Berg, Jan Ludvig Lyche, Azemira Sabaredzovic, Line Smastuen Haug, Oddvar Myhre, Karin Elisabeth Zimmer, Ragnhild Elisabeth Paulsen, Erik Ropstad, Fernando Boix
Summary: Persistent organic pollutants (POPs) were found to reach the fetal brain, with differences observed in the distribution speed between different compounds. PFASs displayed slow elimination and high persistence in the brain, while OCPs and PCBs showed high levels relative to the dose administrated. Chicken embryos proved to be a suitable model for studying the distribution of POPs in the developing brain.
Article
Environmental Sciences
Sophie Mentzel, Merete Grung, Knut Erik Tollefsen, Marianne Stenrod, Karina Petersen, S. Jannicke Moe
Summary: This study explores the application of probabilistic risk assessment approaches in environmental risk assessment of chemicals, demonstrating the potential of Bayesian network modeling as an alternative to traditional risk calculation.
INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT
(2022)
Article
Computer Science, Theory & Methods
Nello Blaser, Morten Brun
Summary: This article presents a method for efficiently computing relative Cech persistent homology in low dimensional Euclidean space by introducing the concept of relative Delaunay-Cech complex.
DISCRETE & COMPUTATIONAL GEOMETRY
(2022)
Article
Multidisciplinary Sciences
Benedicte Sjo Tislevoll, Monica Hellesoy, Oda Helen Eck Fagerholt, Stein-Erik Gullaksen, Aashish Srivastava, Even Birkeland, Dimitrios Kleftogiannis, Pilar Ayuda-Duran, Laure Piechaczyk, Dagim Shiferaw Tadele, Jorn Skavland, Baliakas Panagiotis, Randi Hovland, Vibeke Andresen, Ole Morten Seternes, Tor Henrik Anderson Tvedt, Nima Aghaeepour, Sonia Gavasso, Kimmo Porkka, Inge Jonassen, Yngvar Floisand, Jorrit Enserink, Nello Blaser, Bjorn Tore Gjertsen
Summary: In this study, the initial signaling response to standard induction chemotherapy in 32 acute myeloid leukemia (AML) patients was investigated using 36-dimensional mass cytometry. The reduction of extracellular-signal-regulated kinase (ERK) 1/2 and p38 mitogen-activated protein kinase (MAPK) phosphorylation in the myeloid cell compartment 24 h post-chemotherapy was found to be a significant predictor of patient 5-year overall survival in this cohort. This study demonstrates the value of mass cytometry in early response evaluation in AML and highlights the potential of functional signaling analyses in precision oncology diagnostics.
NATURE COMMUNICATIONS
(2023)
Article
Environmental Sciences
Essa A. Khan, Randi Gronnestad, Ase Krokje, Zdenka Bartosov, Silje Modahl Johanson, Mette H. B. Mueller, Augustine Arukwe
Summary: In this study, we investigated the effects of per- and polyfluoroalkyl substances (PFAS) mixture exposure on liver lipid homeostasis in A/J mice. The mice were fed environmentally relevant concentrations of the PFAS mixture for 10 weeks. The results showed that PFAS accumulation in the liver led to hepatotoxic effects, interference with membrane lipid profile and homeostasis, oxidative stress, and alterations in lipid metabolism, potentially impacting the general health and physiology of exposed animals and humans.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Engineering, Environmental
Bjorn Henrik Hansen, Augustine Arukwe, Hannah Marie Knutsen, Kaja Skarpnord, Julia Farkas, Lara Veylit, Raymond Nepstad, Essa Ahsan Khan, Trond Nordtug, Lisbet Sorensen
Summary: Intentional discharges of produced water from oil production platforms to the marine environment contain a complex mixture of toxicants, including polycyclic aromatic hydrocarbons (PAHs). Early life stages of fish are highly sensitive to petrogenic exposure, and short-term exposure during critical periods of embryonic development may have detrimental effects on larvae health and survival. However, why different periods are more sensitive to exposure than others are not fully understood.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Samuel A. Welch, S. Jannicke Moe, Mohammad N. Sharikabad, Knut Erik Tollefsen, Kristine Olsen, Merete Grung
Summary: Environmental risk assessment (ERA) of pharmaceuticals relies on measured environmental concentrations, but data is often sparse. Predicted environmental concentrations (PECs), calculated from sales weights, provide an alternative, but usually only cover prescription sales. In this study, approximately 200 active pharmaceutical ingredients (APIs) in Norway were ranked based on sales PECs to assess environmental risk. Additional wholesale and veterinary data were compared to evaluate their impact on exposure and risk predictions. The study also investigated the persistence, mobility, and bioaccumulation of the APIs. The findings suggest that sales PECs are an efficient option for ERA, although there are limitations due to data availability and uncertainty quantification.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2023)
Correction
Multidisciplinary Sciences
Benedicte Sjo Tislevoll, Monica Hellesoy, Oda Helen Eck Fagerholt, Stein-Erik Gullaksen, Aashish Srivastava, Even Birkeland, Dimitrios Kleftogiannis, Pilar Ayuda-Duran, Laure Piechaczyk, Dagim Shiferaw Tadele, Jorn Skavland, Panagotis Baliakas, Randi Hovland, Vibeke Andresen, Ole Morten Seternes, Tor Henrik Anderson Tvedt, Nima Aghaeepour, Sonia Gavasso, Kimmo Porkka, Inge Jonassen, Yngvar Floisand, Jorrit Enserink, Nello Blaser, Bjorn Tore Gjertsen
NATURE COMMUNICATIONS
(2023)
Article
Physiology
Marta Eide, Anders Goksoyr, Fekadu Yadetie, Alejandra Gilabert, Zdenka Bartosova, Havard G. Froysa, Shirin Fallahi, Xiaokang Zhang, Nello Blaser, Inge Jonassen, Per Bruheim, Guttorm Alendal, Morten Brun, Cinta Porte, Odd Andre Karlsen
Summary: The involvement of Ppar a and b subtypes in lipid metabolism regulation in Atlantic cod was studied using two model agonists. WY-14,643 and GW501516 were found to activate Ppar a and b, affecting genes in lipid metabolism pathways and inducing changes in lipid composition.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Environmental Sciences
Umar M. Bello, Mary-Cathrine Madekurozwa, Hermanus B. Groenewald, Augustine Arukwe, Tom A. Aire
Summary: This study investigated the effects of DBP exposure on the testes of adult male quails. The results showed that high doses of DBP led to significant decreases in seminiferous tubular diameter and epithelial height, as well as structural changes in the Leydig cells. These findings suggest that DBP exposure may impair the reproductive system of adult birds.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Imaging Science & Photographic Technology
Simeon Mayala, Ida Herdlevaer, Jonas Bull Haugsoen, Shamundeeswari Anandan, Nello Blaser, Sonia Gavasso, Morten Brun
Summary: This paper proposes a graph-based unsupervised brain segmentation method that can segment 3D MRI images into brain, non-brain tissues, and background. It shows comparable results to state-of-the-art methods but does not require labels.
JOURNAL OF IMAGING
(2022)
Article
Environmental Sciences
Emily Curren, Sandric Chee Yew Leong
Summary: Microplastics in marine ecosystems serve as microhabitats for diverse toxic plankton species, including viable resting cysts of dinoflagellates. The diversity of plankton communities on the plastisphere is influenced by anthropogenic factors. This study highlights the importance of plastics as vectors for the transport of harmful opportunistic species in the marine environment.
MARINE ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Vladimir G. Dvoretsky, Alexander G. Dvoretsky
Summary: The Barents Sea, as the largest Arctic shelf region, plays a vital role in supporting commercial fisheries. The ecosystem of this region is significantly influenced by both warm Atlantic Water (AW) and cold Arctic Water (ARW), resulting in distinct frontal zones. This study found that copepod populations, particularly herbivorous copepods, were most abundant and productive in the Polar Front, as well as in the eastern frontal zones. The geographic positions of sampling stations, depth, and chlorophyll a concentration were identified as the main factors influencing copepod biomass and production.
MARINE ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Alberto Rovellini, Charlotte L. Mortimer, Matthew R. Dunn, Elizabeth A. Fulton, Jamaluddin Jompa, Abdul Haris, James J. Bell
Summary: This study compared the structural complexity of coral- and sponge-dominated areas of an Indonesian coral reef using 3D photogrammetry. The results showed that smaller-scale refugia were reduced in sponge-dominated reefs, potentially impacting smaller reef fauna.
MARINE ENVIRONMENTAL RESEARCH
(2024)