Saponin‐enriched extracts from body wall and Cuvierian tubule of Holothuria leucospilota reduce fat accumulation and suppress lipogenesis in Caenorhabditis elegans

Holothuria scabra extracts possess anti-oxidant activity and promote stress resistance and lifespan extension in Caenorhabditis elegans

(2018) Prapaporn Jattujan et al.   EXPERIMENTAL GERONTOLOGY

Saponins enriched in the epidermal layer of Holothuria leucospilota body wall

(2018) Morakot Sroyraya et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Holothuria scabra extracts exhibit anti-Parkinson potential in C. elegans: A model for anti-Parkinson testing

(2017) Pawanrat Chalorak et al.   NUTRITIONAL NEUROSCIENCE

The cAMP-PKA pathway-mediated fat mobilization is required for cold tolerance in C. elegans

(2017) Fang Liu et al.   Scientific Reports

AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue

(2016) Sun-Joong Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Effects of Saponins on Lipid Metabolism: A Review of Potential Health Benefits in the Treatment of Obesity

(2016) Mariangela Marrelli et al.   MOLECULES

AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators

(2016) Elizabeth Moreno-Arriola et al.   PLoS One

Regulation of AMP-activated protein kinase by natural and synthetic activators

(2016) David Grahame Hardie   Acta Pharmaceutica Sinica B

CCAAT/enhancer-binding protein CEBP-2 controls fat consumption and fatty acid desaturation in Caenorhabditis elegans

(2015) Xiao-Ying Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SREBP and MDT-15 protectC. elegansfrom glucose-induced accelerated aging by preventing accumulation of saturated fat

(2015) Dongyeop Lee et al.   GENES & DEVELOPMENT

Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling

(2015) Lu Guo et al.   PHARMACEUTICAL BIOLOGY

Lipolysis and lipases in white adipose tissue – An update

(2015) Andressa Bolsoni-Lopes et al.   Archives of Endocrinology Metabolism

Effects of two sulfated triterpene saponins echinoside A and holothurin A on the inhibition of dietary fat absorption and obesity reduction

(2014) Yuming Wang et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Lipid Droplet Protein LID-1 Mediates ATGL-1-Dependent Lipolysis during Fasting in Caenorhabditis elegans

(2014) J. H. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

(2013) Silvia Bijland et al.   CLINICAL SCIENCE

Saponins from Platycodon grandiflorum inhibit hepatic lipogenesis through induction of SIRT1 and activation of AMP-activated protein kinase in high-glucose-induced HepG2 cells

(2013) Yong Pil Hwang et al.   FOOD CHEMISTRY

Effects of Bioactive Components of Sea Cucumber on the Serum, Liver Lipid Profile and Lipid Absorption

(2012) Xiao-Qian HU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

LOC66273 Isoform 2, a Novel Protein Highly Expressed in White Adipose Tissue, Induces Adipogenesis in 3T3-L1 Cells

(2012) Xi Ma et al.   JOURNAL OF NUTRITION

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Stephen S Lim et al.   LANCET

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Caenorhabditis elegans as a model for obesity research

(2011) J Zheng et al.   INTERNATIONAL JOURNAL OF OBESITY

Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress

(2011) Tiejie Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Dietary saponins of sea cucumber alleviate orotic acid-induced fatty liver in rats via PPARα and SREBP-1c signaling

(2010) Xiao-Qian Hu et al.   Lipids in Health and Disease

Qualitative and Quantitative Saponin Contents in Five Sea Cucumbers from the Indian Ocean

(2010) Séverine Van Dyck et al.   Marine Drugs

SiRNA against Fabp5 induces 3T3-L1 cells apoptosis during adipocytic induction

(2010) Xi Ma et al.   MOLECULAR BIOLOGY REPORTS

Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression

(2009) Seung-Jae Lee et al.   Cell Metabolism

C. elegans as Model for the Study of High Glucose- Mediated Life Span Reduction

(2009) A. Schlotterer et al.   DIABETES

Fat accumulation in Caenorhabditis elegans is mediated by SREBP homolog SBP-1

(2009) Toshihisa Nomura et al.   Genes and Nutrition

Fat synthesis and adiposity regulation in Caenorhabditis elegans

(2009) Jennifer L. Watts   TRENDS IN ENDOCRINOLOGY AND METABOLISM