YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility

Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9

(2018) Hiroki Goto et al.   DEVELOPMENT

Skeletal cell YAP and TAZ combinatorially promote bone development

(2018) Christopher D. Kegelman et al.   FASEB JOURNAL

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

(2018) Filipa Neto et al.   eLife

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

(2017) Jongshin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation

(2017) K Otsubo et al.   ONCOGENE

YAP/TAZ-CDC42 signaling regulates vascular tip cell migration

(2017) Masahide Sakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis

(2017) Yiting Qiao et al.   Cell Reports

Endothelial Progenitors: A Consensus Statement on Nomenclature

(2017) Reinhold J. Medina et al.   Stem Cells Translational Medicine

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

(2017) Chuwen Lin et al.   eLife

A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency

(2017) Courtney M. Caroti et al.   Scientific Reports

MRTF potentiates TEAD‐YAP transcriptional activity causing metastasis

(2016) Tackhoon Kim et al.   EMBO JOURNAL

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

Confocal reference free traction force microscopy

(2016) Martin Bergert et al.   Nature Communications

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

(2015) Fei Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Kymographic Imaging of the Elastic Modulus of Epithelial Cells during the Onset of Migration

(2015) Esra Roan et al.   BIOPHYSICAL JOURNAL

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

(2015) E. Enzo et al.   EMBO JOURNAL

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

(2015) Toshiro Moroishi et al.   GENES & DEVELOPMENT

YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers

(2015) Giorgio G. Galli et al.   MOLECULAR CELL

YAP is essential for tissue tension to ensure vertebrate 3D body shape

(2015) Sean Porazinski et al.   NATURE

YAP Regulates S-Phase Entry in Endothelial Cells

(2015) Zhewei Shen et al.   PLoS One

Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2

(2015) Hyun-Jung Choi et al.   Nature Communications

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

Mitogen-Activated Protein Kinase Phosphatase-1 Promotes Neovascularization and Angiogenic Gene Expression

(2014) Joel D. Boerckel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

(2014) C. Esnault et al.   GENES & DEVELOPMENT

The role of the interaction of the vinculin proline-rich linker region with vinexin   in sensing the stiffness of the extracellular matrix

(2014) H. Yamashita et al.   JOURNAL OF CELL SCIENCE

In vivoroles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction

(2014) Cai-Ping Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

(2013) Sourav Banerjee et al.   BIOCHEMICAL JOURNAL

Collagen-Polymer Guidance of Vessel Network Formation and Stabilization by Endothelial Colony Forming Cells In Vitro

(2013) Catherine F. Whittington et al.   MACROMOLECULAR BIOSCIENCE

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Molecular mechanisms of cellular mechanosensing

(2013) Tianzhi Luo et al.   NATURE MATERIALS

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template

(2012) Patrick W. Oakes et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Distinct Recycling of Active and Inactive β1 Integrins

(2012) Antti Arjonen et al.   TRAFFIC

Hippo pathway regulation by cell morphology and stress fibers

(2011) K.-I. Wada et al.   DEVELOPMENT

Changes in cell migration of mesenchymal cells during osteogenic differentiation

(2011) Masanori Ichida et al.   FEBS LETTERS

An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers

(2011) T. Vallenius et al.   JOURNAL OF CELL SCIENCE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

Polymerization and matrix physical properties as important design considerations for soluble collagen formulations

(2010) S.T. Kreger et al.   BIOPOLYMERS

Collagen oligomers modulate physical and biological properties of three-dimensional self-assembled matrices

(2010) J. L. Bailey et al.   BIOPOLYMERS

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Collagen matrix physical properties modulate endothelial colony forming cell-derived vessels in vivo

(2010) P.J. Critser et al.   MICROVASCULAR RESEARCH

New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion

(2010) A. Zagorska et al.   Science Signaling

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

Cell-autonomous requirement for  1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

(2008) T. R. Carlson et al.   DEVELOPMENT

TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

Identification of a novel substrate for TNFα-induced kinase NUAK2

(2007) Hiroyuki Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS