Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

(2013) Eeva M. Sommer et al.   BIOCHEMICAL JOURNAL

Terminal Axon Branching Is Regulated by the LKB1-NUAK1 Kinase Pathway via Presynaptic Mitochondrial Capture

(2013) Julien Courchet et al.   CELL

Transcription Factor/microRNA Axis Blocks Melanoma Invasion Program by miR-211 Targeting NUAK1

(2013) Rachel E. Bell et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Synthesis and structure–activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases

(2012) Edward G. McIver et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Neural tube defects by NUAK1 and NUAK2 double mutation

(2012) Tomomi Ohmura et al.   DEVELOPMENTAL DYNAMICS

ARK5 promotes glioma cell invasion, and its elevated expression is correlated with poor clinical outcome

(2012) Shijun Lu et al.   EUROPEAN JOURNAL OF CANCER

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

(2012) K. F. MacKenzie et al.   JOURNAL OF IMMUNOLOGY

Deregulated MYC expression induces dependence upon AMPK-related kinase 5

(2012) Lidan Liu et al.   NATURE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

(2012) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel cross-talk within the IKK family controls innate immunity

(2011) Kristopher Clark et al.   BIOCHEMICAL JOURNAL

High-Throughput Kinase Profiling: A More Efficient Approach toward the Discovery of New Kinase Inhibitors

(2011) Chandrasekhar V. Miduturu et al.   CHEMISTRY & BIOLOGY

An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers

(2011) T. Vallenius et al.   JOURNAL OF CELL SCIENCE

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2

(2011) Xianming Deng et al.   Nature Chemical Biology

A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation

(2011) X Hou et al.   ONCOGENE

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

(2010) Ayaz Najafov et al.   BIOCHEMICAL JOURNAL

New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion

(2010) A. Zagorska et al.   Science Signaling

Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease

(2009) R. Jeremy Nichols et al.   BIOCHEMICAL JOURNAL

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

(2009) Nicolas Humbert et al.   EMBO JOURNAL

Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ

(2009) Kristopher Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

(2009) Wenjun Zhou et al.   NATURE

The tau of MARK: a polarized view of the cytoskeleton

(2009) Dorthe Matenia et al.   TRENDS IN BIOCHEMICAL SCIENCES