The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells
出版年份 2019 全文链接
标题
The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 4, Pages 955
出版商
MDPI AG
发表日期
2019-02-23
DOI
10.3390/ijms20040955
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Simvastatin Strongly Augments Proapoptotic, Anti-inflammatory and Cytotoxic Activity of Oxicam Derivatives in Doxorubicin-resistant Colon Cancer Cells
- (2019) KAMILA ŚRODA-POMIANEK et al. ANTICANCER RESEARCH
- Cytotoxic and multidrug resistance reversal activity of phenothiazine derivative is strongly enhanced by theobromine, a phytochemical from cocoa
- (2019) Kamila Środa-Pomianek et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine
- (2018) Mahendra Seervi et al. BIOMEDICINE & PHARMACOTHERAPY
- Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives
- (2018) Kamila Środa-Pomianek et al. BIOMEDICINE & PHARMACOTHERAPY
- Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice
- (2018) Baodong Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Effects of simvastatin on nuclear receptors, drug metabolizing enzymes and transporters expression in Human Umbilical Vein Endothelial Cells
- (2018) Joanna Łapczuk-Romańska et al. Pharmacological Reports
- MDR reversal and pro-apoptotic effects of statins and statins combined with flavonoids in colon cancer cells
- (2018) Anna Palko-Łabuz et al. BIOMEDICINE & PHARMACOTHERAPY
- The possible ameliorative effect of simvastatin versus sulfasalazine on acetic acid induced ulcerative colitis in adult rats
- (2018) NA Soliman et al. CHEMICO-BIOLOGICAL INTERACTIONS
- The Anticancer Activity of the Old Neuroleptic Phenothiazine-type Drug Thioridazine
- (2016) GABRIELLA SPENGLER et al. ANTICANCER RESEARCH
- Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells
- (2016) Alice C. Rodrigues et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Sensitivity of Gastric Cancer Cells to Chemotherapy Drugs in Elderly Patients and Its Correlation with Cyclooxygenase-2 Expression
- (2015) Zhen-Qin Qiu et al. Asian Pacific Journal of Cancer Prevention
- Molecular mechanism underlying the anticancer effect of simvastatin on MDA-MB-231 human breast cancer cells
- (2015) YUAN-YUAN SHEN et al. Molecular Medicine Reports
- Statins inhibit ABCB1 and ABCG2 drug transporter activity in chronic myeloid leukemia cells and potentiate antileukemic effects of imatinib
- (2014) Eliza Glodkowska-Mrowka et al. EXPERIMENTAL HEMATOLOGY
- Design of Novel Potent Antihyperlipidemic Agents with Antioxidant/Anti-inflammatory Properties: Exploiting Phenothiazine’s Strong Antioxidant Activity
- (2014) Alexios N. Matralis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Simvastatin attenuates angiotensin II-induced inflammation and oxidative stress in human mesangial cells
- (2014) FENGXIANG ZHANG et al. Molecular Medicine Reports
- HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway
- (2013) X-F Qi et al. Cell Death & Disease
- Proveblue (Methylene Blue) as an Antimalarial Agent:In VitroSynergy with Dihydroartemisinin and Atorvastatin
- (2012) Jérôme Dormoi et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Multidrug Resistance Reversal and Apoptosis Induction in Human Colon Cancer Cells by Some Flavonoids Present in Citrus Plants
- (2012) Olga Wesołowska et al. JOURNAL OF NATURAL PRODUCTS
- Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression
- (2011) CARMINE SPAMPANATO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Chemosensitization by phenothiazines in human lung cancer cells: impaired resolution of γH2AX and increased oxidative stress elicit apoptosis associated with lysosomal expansion and intense vacuolation
- (2011) D Zong et al. Cell Death & Disease
- 8-Prenylnaringenin is an inhibitor of multidrug resistance-associated transporters, P-glycoprotein and MRP1
- (2010) Olga Wesołowska et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Differential interactions between statins and P-glycoprotein: Implications for exploiting statins as anticancer agents
- (2010) Carolyn A. Goard et al. INTERNATIONAL JOURNAL OF CANCER
- Synthesis and structure–activity relationships of phenothiazine carboxylic acids having pyrimidine-dione as novel histamine H1 antagonists
- (2009) Katsumi Kubota et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Double impact on p-glycoprotein by statins enhances doxorubicin cytotoxicity in human neuroblastoma cells
- (2009) Evelyn Sieczkowski et al. INTERNATIONAL JOURNAL OF CANCER
- Statins can modulate effectiveness of antitumor therapeutic modalities
- (2009) Marek Jakobisiak et al. MEDICINAL RESEARCH REVIEWS
- Induced Neuroprotection Independently From PrPSc Accumulation in a Mouse Model for Prion Disease Treated With Simvastatin
- (2008) Yaron Haviv et al. ARCHIVES OF NEUROLOGY
- Statin Induces Apoptosis and Cell Growth Arrest in Prostate Cancer Cells
- (2008) A. Hoque et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- An overview of cancer multidrug resistance: a still unsolved problem
- (2008) H. Lage CELLULAR AND MOLECULAR LIFE SCIENCES
- Development of inhibitors of ATP-binding cassette drug transporters – present status and challenges
- (2008) Suneet Shukla et al. Expert Opinion on Drug Metabolism & Toxicology
- Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells
- (2008) Hang Xiao et al. INTERNATIONAL JOURNAL OF CANCER
- Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice
- (2008) Soo-Jeong Cho et al. INTERNATIONAL JOURNAL OF CANCER
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