Macrophages in wound healing: activation and plasticity

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Niche signals and transcription factors involved in tissue-resident macrophage development

(2018) Wouter T'Jonck et al.   CELLULAR IMMUNOLOGY

Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders

(2018) Gabrielle M. Pine et al.   CYTOKINE

Hematopoietic cell-derived RELMα regulates hookworm immunity through effects on macrophages

(2018) Hashini M. Batugedara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A sensitive flow cytometric method for multi-parametric analysis of microRNA, messenger RNA and protein in single cells

(2018) Chunfai Lai et al.   METHODS

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

(2018) Shih-Yen Weng et al.   EBioMedicine

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

(2018) Charlotte L. Scott et al.   IMMUNITY

Developmental and Functional Heterogeneity of Monocytes

(2018) Martin Guilliams et al.   IMMUNITY

Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

(2018) Tara E. Sutherland et al.   PLoS Pathogens

Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells

(2017) Lidia Bosurgi et al.   SCIENCE

Specific repair by discerning macrophages

(2017) Tiffany Bouchery et al.   SCIENCE

Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver

(2017) Carlos M. Minutti et al.   SCIENCE

Tissue-specific contribution of macrophages to wound healing

(2017) Carlos M. Minutti et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts

(2017) Zhensen Zhu et al.   WOUND REPAIR AND REGENERATION

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

(2017) Dominik Rückerl et al.   PLoS Pathogens

A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair

(2016) Jing Wang et al.   CELL

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

(2016) Stanley Ching-Cheng Huang et al.   IMMUNITY

Clearance of apoptotic neutrophils and resolution of inflammation

(2016) Mallary C. Greenlee-Wacker   IMMUNOLOGICAL REVIEWS

Immune polarization by hookworms: taking cues from T helper type 2, type 2 innate lymphoid cells and alternatively activated macrophages

(2016) Meera G. Nair et al.   IMMUNOLOGY

Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection

(2016) Gang Chen et al.   INFECTION AND IMMUNITY

Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice

(2015) Rei Takahashi et al.   Geriatrics & Gerontology International

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

IRAK-M Promotes Alternative Macrophage Activation and Fibroproliferation in Bleomycin-Induced Lung Injury

(2015) Megan N. Ballinger et al.   JOURNAL OF IMMUNOLOGY

Macrophage PPARγ and impaired wound healing in type 2 diabetes

(2015) Rita E Mirza et al.   JOURNAL OF PATHOLOGY

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

(2015) L A Borthwick et al.   Mucosal Immunology

The role of tissue resident cells in neutrophil recruitment

(2015) Nancy D. Kim et al.   TRENDS IN IMMUNOLOGY

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair

(2015) Julia Esser-von Bieren et al.   PLoS Pathogens

Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis

(2014) Eimear Linehan et al.   AGING CELL

A2B Adenosine Receptor Induces Protective Antihelminth Type 2 Immune Responses

(2014) Nirav Patel et al.   Cell Host & Microbe

Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs

(2014) Cecilia A. Hinojosa et al.   EXPERIMENTAL GERONTOLOGY

Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling

(2014) Chris P. Verschoor et al.   HUMAN IMMUNOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Mononuclear phagocytes of the intestine, the skin, and the lung

(2014) Charlotte L. Scott et al.   IMMUNOLOGICAL REVIEWS

Engulfment of Apoptotic Cells by Macrophages: A Role of MicroRNA-21 in the Resolution of Wound Inflammation

(2014) A. Das et al.   JOURNAL OF IMMUNOLOGY

Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nano-Proresolving Medicines

(2014) Hildur H. Arnardottir et al.   JOURNAL OF IMMUNOLOGY

Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity

(2014) Jorming Goh et al.   MECHANISMS OF AGEING AND DEVELOPMENT

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

(2013) Rémi Mounier et al.   Cell Metabolism

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

(2013) Laura Campbell et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

(2013) Luke C. Davies et al.   Nature Communications

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

(2013) Julia Esser-von Bieren et al.   PLoS Pathogens

Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

(2011) Masayuki Ichioka et al.   DIABETES

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis

(2011) Teresa Bellón et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

(2010) U. Schingnitz et al.   JOURNAL OF IMMUNOLOGY

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing

(2009) K. J. Mylonas et al.   JOURNAL OF IMMUNOLOGY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE