Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators

标题
Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators
作者
关键词
P-gp modulators, BCRP modulators, MRP1 modulators, MDR reversers, Pirarubicin uptake, Molecular docking, Human plasma stability, Rhodamine-123 efflux, ATPase activity, Apparent permeability
出版物
出版商
Elsevier BV
发表日期
2019-03-28
DOI
10.1016/j.ejmech.2019.03.054

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