Transient use of a systemic adenosine kinase inhibitor attenuates epilepsy development in mice

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

(2017) Pavel Klein et al.   EPILEPSIA

Epilepsy and astrocyte energy metabolism

(2017) Detlev Boison et al.   GLIA

A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy

(2017) Alina Schidlitzki et al.   Scientific Reports

South (S)- and North (N)-Methanocarba-7-Deazaadenosine Analogues as Inhibitors of Human Adenosine Kinase

(2016) Kiran S. Toti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development

(2015) Matthew L. Diamond et al.   EPILEPSIA

Adenosine kinase deficiency: expanding the clinical spectrum and evaluating therapeutic options

(2015) Christian Staufner et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats

(2015) Theresa A. Lusardi et al.   NEUROPHARMACOLOGY

Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy

(2015) Suzanne F.C. Miller-Delaney et al.   BRAIN

Deep sequencing reveals increased DNA methylation in chronic rat epilepsy

(2013) Katja Kobow et al.   ACTA NEUROPATHOLOGICA

The methylation hypothesis of pharmacoresistance in epilepsy

(2013) Katja Kobow et al.   EPILEPSIA

Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis

(2013) Rebecca L. Williams-Karnesky et al.   JOURNAL OF CLINICAL INVESTIGATION

Glial adenosine kinase – A neuropathological marker of the epileptic brain

(2013) Eleonora Aronica et al.   NEUROCHEMISTRY INTERNATIONAL

Rapamycin Attenuates the Development of Posttraumatic Epilepsy in a Mouse Model of Traumatic Brain Injury

(2013) Dongjun Guo et al.   PLoS One

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

(2012) Carl E. Stafstrom et al.   Frontiers in Pharmacology

Adenosine Kinase Deficiency Disrupts the Methionine Cycle and Causes Hypermethioninemia, Encephalopathy, and Abnormal Liver Function

(2011) Magnus K. Bjursell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Septotemporal Position in the Hippocampal Formation Determines Epileptic and Neurogenic Activity in Temporal Lobe Epilepsy

(2011) U. Haussler et al.   CEREBRAL CORTEX

Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy

(2011) Eleonora Aronica et al.   EPILEPSIA

A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

(2011) Susan A. Masino et al.   JOURNAL OF CLINICAL INVESTIGATION

The ketogenic diet: an appropriate first-line therapy?

(2010) Eric H Kossoff   Expert Review of Neurotherapeutics

Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice

(2009) Tianfu Li et al.   Neuron Glia Biology

How do seizures stop?

(2008) Fred A. Lado et al.   EPILEPSIA