Irisin exerts dual effects on browning and adipogenesis of human white adipocytes

FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

(2015) Xiao-Qing Xiong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

(2015) Mark P. Jedrychowski et al.   Cell Metabolism

Enhanced expression of FNDC5 in human embryonic stem cell-derived neural cells along with relevant embryonic neural tissues

(2015) Fatemeh Ahmadi Ghahrizjani et al.   GENE

Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

(2015) M J Vosselman et al.   INTERNATIONAL JOURNAL OF OBESITY

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

Irisin: A true, circulating hormone

(2015) Stergios A. Polyzos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts

(2015) Chao Xie et al.   PLoS One

Activation of Classical Brown Adipocytes in the Adult Human Perirenal Depot Is Highly Correlated with PRDM16–EHMT1 Complex Expression

(2015) Gaku Nagano et al.   PLoS One

The myokine irisin increases cortical bone mass

(2015) Graziana Colaianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Irisin – a myth rather than an exercise-inducible myokine

(2015) Elke Albrecht et al.   Scientific Reports

IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes

(2015) Rie Asada et al.   Scientific Reports

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

Irisin: ‘fat’ or artefact

(2014) A.B. Crujeiras et al.   CLINICAL ENDOCRINOLOGY

Association between habitual physical activity and brown adipose tissue activity in individuals undergoing PET-CT scan

(2014) Petros C. Dinas et al.   CLINICAL ENDOCRINOLOGY

Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans

(2014) M. Chondronikola et al.   DIABETES

Induced expression of Fndc5 significantly increased cardiomyocyte differentiation rate of mouse embryonic stem cells

(2014) Farzaneh Rabiee et al.   GENE

Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice

(2014) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans

(2014) J Y Huh et al.   INTERNATIONAL JOURNAL OF OBESITY

Browning of white fat: does irisin play a role in humans?

(2014) Manuela Elsen et al.   JOURNAL OF ENDOCRINOLOGY

Characterization of brown adipose tissue in the human perirenal depot

(2014) Per-Arne Svensson et al.   Obesity

Irisin Enhances Osteoblast DifferentiationIn Vitro

(2014) Graziana Colaianni et al.   International Journal of Endocrinology

Irisin

(2013) Ulf Elbelt et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Banting Lecture 2012: Regulation of Adipogenesis: Toward New Therapeutics for Metabolic Disease

(2013) B. M. Spiegelman   DIABETES

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Acquisition of pig intramuscular preadipocytes through dedifferentiation of mature adipocytes and establishment of optimal induction conditions

(2013) W. Sun et al.   GENETICS AND MOLECULAR RESEARCH

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Evidence against a Beneficial Effect of Irisin in Humans

(2013) Silja Raschke et al.   PLoS One

Irisin and FNDC5 in retrospect

(2013) Harold P Erickson   Adipocyte

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

From white to brown fat through the PGC-1 -dependent myokine irisin: implications for diabetes and obesity

(2012) J. I. Castillo-Quan   Disease Models & Mechanisms

Cellular and molecular comparison of redifferentiation of intramuscular- and visceral-adipocyte derived progeny cells

(2012) Jie Chen et al.   International Journal of Biological Sciences

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells

(2012) M.-S. Hashemi et al.   NEUROSCIENCE

The Regulation and Physiology of Mitochondrial Proton Leak

(2011) Ajit S. Divakaruni et al.   PHYSIOLOGY

UCP1 genetic polymorphism (–3826 A/G) diminishes resting energy expenditure and thermoregulatory sympathetic nervous system activity in young females

(2010) N Nagai et al.   INTERNATIONAL JOURNAL OF OBESITY

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Critical regulation of TGF  signaling by Hsp90

(2008) K. H. Wrighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA