Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension

The cancer theory of pulmonary arterial hypertension

(2017) Olivier Boucherat et al.   Pulmonary Circulation

HIPPO–Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension

(2016) Tatiana V. Kudryashova et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

(2016) Thomas Bertero et al.   JOURNAL OF CLINICAL INVESTIGATION

ACE2 overexpression inhibits acquired platinum resistance-induced tumor angiogenesis in NSCLC

(2016) Qijian Cheng et al.   ONCOLOGY REPORTS

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

(2016) Fuqin Fan et al.   Science Translational Medicine

Combination therapy versus monotherapy for pulmonary arterial hypertension: a meta-analysis

(2016) Annie Christine Lajoie et al.   Lancet Respiratory Medicine

Expression of MAS1 in breast cancer

(2015) Yi Luo et al.   CANCER SCIENCE

Angiotensin-Converting Enzyme 2 Attenuates Bleomycin-Induced Lung Fibrosis in Mice

(2015) Lifang Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway

(2015) U. Ehmer et al.   MOLECULAR CANCER RESEARCH

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(2015) Yanping Liu et al.   MOLECULAR MEDICINE

Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis prevents lipopolysaccharide–induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF–κB pathways

(2015) Yingchuan Li et al.   Scientific Reports

Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit

(2015) Thomas Bertero et al.   Cell Reports

The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes

(2014) D O Wennmann et al.   Cell Death & Disease

Mammalian Target of Rapamycin Complex 2 (mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension

(2013) Dmitry A. Goncharov et al.   CIRCULATION

ACE2 Activation Confers Endothelial Protection and Attenuates Neointimal Lesions in Prevention of Severe Pulmonary Arterial Hypertension in Rats

(2013) Gang Li et al.   LUNG

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Cell cycle dependence of ACE-2 explains downregulation in idiopathic pulmonary fibrosis

(2012) Bruce D. Uhal et al.   EUROPEAN RESPIRATORY JOURNAL

ACE2, a promising therapeutic target for pulmonary hypertension

(2011) Vinayak Shenoy et al.   CURRENT OPINION IN PHARMACOLOGY

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

(2011) Wilbert S. Aronow et al.   Journal of the American Society of Hypertension

Strategic Plan for Lung Vascular Research

(2010) Serpil Erzurum et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Connective Tissue Growth Factor Confers Drug Resistance in Breast Cancer through Concomitant Up-regulation of Bcl-xL and cIAP1

(2009) M.-Y. Wang et al.   CANCER RESEARCH

Prevention of Pulmonary Hypertension by Angiotensin-Converting Enzyme 2 Gene Transfer

(2009) Yoriko Yamazato et al.   HYPERTENSION