Transcriptional and epigenetic regulation of immune tolerance: roles of the NF-κB family members

Genetic and epigenetic influences on the loss of tolerance in autoimmunity

(2018) Peng Zhang et al.   Cellular & Molecular Immunology

Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation

(2018) Xiang Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

OX40 Costimulation Inhibits Foxp3 Expression and Treg Induction via BATF3-Dependent and Independent Mechanisms

(2018) Xiaolong Zhang et al.   Cell Reports

NF-kappaB: Two Sides of the Same Coin

(2018) Bruno Pires et al.   Genes

Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model

(2018) Lorenzo Schiaffino et al.   Scientific Reports

BRD4 and Cancer: going beyond transcriptional regulation

(2018) Benedetta Donati et al.   Molecular Cancer

Long non-coding RNA: a versatile regulator of the nuclear factor-κB signalling circuit

(2017) Xiaohua Mao et al.   IMMUNOLOGY

The cancer epigenome: Concepts, challenges, and therapeutic opportunities

(2017) Mark A. Dawson   SCIENCE

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

(2017) Paola A. Betancur et al.   Nature Communications

The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways

(2016) Xiang Xiao et al.   IMMUNITY

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

(2016) Agnieszka Mamińska et al.   Science Signaling

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100

(2016) Amanda J. Fusco et al.   Science Signaling

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

(2016) Agnieszka Mamińska et al.   Science Signaling

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100

(2016) Amanda J. Fusco et al.   Science Signaling

Early T Cell Activation: Integrating Biochemical, Structural, and Biophysical Cues

(2015) Bernard Malissen et al.   Annual Review of Immunology

Functional coupling between writers, erasers and readers of histone and DNA methylation

(2015) Idelisse Ortiz Torres et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation

(2015) Xiang Xiao et al.   Nature Communications

Complex interactions of transcription factors in mediating cytokine biology in T cells

(2014) Peng Li et al.   IMMUNOLOGICAL REVIEWS

T Cell-Intrinsic Function of the Noncanonical NF- B Pathway in the Regulation of GM-CSF Expression and Experimental Autoimmune Encephalomyelitis Pathogenesis

(2014) J. Yu et al.   JOURNAL OF IMMUNOLOGY

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

(2014) Jonathan D. Brown et al.   MOLECULAR CELL

Histone core modifications regulating nucleosome structure and dynamics

(2014) Peter Tessarz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Regulation of NF-κB by ubiquitination

(2013) Jueqi Chen et al.   CURRENT OPINION IN IMMUNOLOGY

Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme

(2013) Timothy T. Lu et al.   IMMUNITY

Epigenetic regulation of inducible gene expression in the immune system

(2013) Pek Siew Lim et al.   IMMUNOLOGY

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

(2013) Hongbo Hu et al.   NATURE

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Regulation of NF-κB signaling by the A20 deubiquitinase

(2012) Noula Shembade et al.   Cellular & Molecular Immunology

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

(2012) Irving C. Allen et al.   IMMUNITY

IKK biology

(2012) Fei Liu et al.   IMMUNOLOGICAL REVIEWS

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors

(2012) Stephen T. Smale   IMMUNOLOGICAL REVIEWS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window

(2012) Annamaria Lanzillotta et al.   NEUROBIOLOGY OF DISEASE

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

(2011) Bahram Razani et al.   IMMUNOLOGICAL REVIEWS

RelA Ser276 Phosphorylation-Coupled Lys310 Acetylation Controls Transcriptional Elongation of Inflammatory Cytokines in Respiratory Syncytial Virus Infection

(2011) A. R. Brasier et al.   JOURNAL OF VIROLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1

(2011) Y Liu et al.   ONCOGENE

MicroRNAs in NF- B signaling

(2011) X. Ma et al.   Journal of Molecular Cell Biology

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Linear polyubiquitination: a new regulator of NF-κB activation

(2009) Kazuhiro Iwai et al.   EMBO REPORTS

A20 Negatively Regulates T Cell Receptor Signaling to NF- B by Cleaving Malt1 Ubiquitin Chains

(2009) M. Duwel et al.   JOURNAL OF IMMUNOLOGY

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation

(2008) L. A. Puto et al.   GENES & DEVELOPMENT

Generation and Activation of Multiple Dimeric Transcription Factors within the NF- B Signaling System

(2008) S. Basak et al.   MOLECULAR AND CELLULAR BIOLOGY