Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
出版年份 2019 全文链接
标题
Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2019-01-28
DOI
10.1038/s41418-019-0278-9
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield
- (2018) Muhammad Zaeem Noman et al. Autophagy
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- Adoptive transfer of natural killer cells in combination with chemotherapy improves outcomes of patients with locally advanced colon carcinoma
- (2018) Lingyu Li et al. CYTOTHERAPY
- Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells
- (2018) Adam Cribbs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
- (2018) Suresh Bugide et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
- (2018) Sergey Karakashev et al. Nature Communications
- MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation
- (2017) Hailong Liu et al. MOLECULAR CANCER RESEARCH
- Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models
- (2017) Elayne Chan-Penebre et al. MOLECULAR CANCER THERAPEUTICS
- EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms
- (2017) N Venkatesan et al. ONCOGENE
- UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome
- (2017) Karl B. Shpargel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PRC2-mediated repression of SMARCA2 predicts EZH2 inhibitor activity in SWI/SNF mutant tumors
- (2017) Thomas Januario et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma
- (2017) Yong Chen et al. OncoTargets and Therapy
- Cisplatin-enriching cancer stem cells confer multidrug resistance in non-small cell lung cancer via enhancing TRIB1/HDAC activity
- (2017) Lihui Wang et al. Cell Death & Disease
- Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control
- (2017) C Pawlyn et al. Blood Cancer Journal
- The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy
- (2017) Daniel Zingg et al. Cell Reports
- The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma
- (2017) Amrita M. Nargund et al. Cell Reports
- Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs
- (2017) Anna Kozlowska et al. Journal of Cancer
- Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma
- (2017) Thomas Powles et al. JAMA Oncology
- EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma
- (2016) Junli Yan et al. BLOOD
- Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells
- (2016) Margarida Ferreira-Teixeira et al. BMC Medicine
- EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
- (2016) Wendy Béguelin et al. CANCER CELL
- Enhanced Sensitivity of Cancer Stem Cells to Chemotherapy Using Functionalized Mesoporous Silica Nanoparticles
- (2016) Zhenzhen Chen et al. MOLECULAR PHARMACEUTICS
- ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice
- (2016) Radhika Mathur et al. NATURE GENETICS
- Enhancer of zeste homolog 2 (EZH2) expression in bladder cancer
- (2016) Joshua I. Warrick et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- JAK3-mediated phosphorylation of EZH2: a novel mechanism of non-canonical EZH2 activation and oncogenic function
- (2016) Theodoros Karantanos et al. Translational Cancer Research
- Enhancer of zeste homolog 2 (EZH2) promotes tumour cell migration and invasion via epigenetic repression of E-cadherin in renal cell carcinoma
- (2015) Li Liu et al. BJU INTERNATIONAL
- Molecular Pathways: Targeting Cancer Stem Cells Awakened by Chemotherapy to Abrogate Tumor Repopulation
- (2015) K. S. Chan CLINICAL CANCER RESEARCH
- Activation of EZH2 and SUZ12 Regulated by E2F1 Predicts the Disease Progression and Aggressive Characteristics of Bladder Cancer
- (2015) S.-R. Lee et al. CLINICAL CANCER RESEARCH
- Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma
- (2015) I. Aldiri et al. DEVELOPMENT
- Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
- (2015) Dongjun Peng et al. NATURE
- SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2
- (2015) Kimberly H Kim et al. NATURE MEDICINE
- Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
- (2015) Benjamin G Bitler et al. NATURE MEDICINE
- Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity
- (2015) Jie Yin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
- (2015) Yang-Fan Lv et al. Scientific Reports
- EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner
- (2015) Sung-Hak Kim et al. Stem Cell Reports
- In Vivo Disruption of an Rb-E2F-Ezh2 Signaling Loop Causes Bladder Cancer
- (2014) M. Santos et al. CANCER RESEARCH
- Methylation of NKG2D ligands contributes to immune system evasion in acute myeloid leukemia
- (2014) A Baragaño Raneros et al. GENES AND IMMUNITY
- EZH2 Represses Target Genes through H3K27-Dependent and H3K27-Independent Mechanisms in Hepatocellular Carcinoma
- (2014) Shu-Bin Gao et al. MOLECULAR CANCER RESEARCH
- Bladder cancers arise from distinct urothelial sub-populations
- (2014) Jason Van Batavia et al. NATURE CELL BIOLOGY
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- EZH2-Mediated Inactivation of IFN-γ-JAK-STAT1 Signaling Is an Effective Therapeutic Target in MYC-Driven Prostate Cancer
- (2014) Zhen Ning Wee et al. Cell Reports
- Comet assay measures of DNA damage are predictive of bladder cancer cell treatment sensitivityin vitroand outcomein vivo
- (2013) Karen J. Bowman et al. INTERNATIONAL JOURNAL OF CANCER
- Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
- (2013) S. K. Knutson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ovarian Cancer Stem Cell-Like Side Populations Are Enriched Following Chemotherapy and Overexpress EZH2
- (2011) S. Rizzo et al. MOLECULAR CANCER THERAPEUTICS
- Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
- (2011) Yaoting Gui et al. NATURE GENETICS
- Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation
- (2010) Boris G. Wilson et al. CANCER CELL
- Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium
- (2010) Guru Sonpavde et al. LANCET ONCOLOGY
- NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy
- (2008) Nadia Guerra et al. IMMUNITY
- SWI/SNF Mediates Polycomb Eviction and Epigenetic Reprogramming of the INK4b-ARF-INK4a Locus
- (2008) S. K. Kia et al. MOLECULAR AND CELLULAR BIOLOGY
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