Molecular tumor analysis and liquid biopsy: a feasibility investigation analyzing circulating tumor DNA in patients with central nervous system lymphomas

2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity

(2017) Parker L. Sulkowski et al.   Science Translational Medicine

Non-invasive detection of somatic mutations using next-generation sequencing in primary central nervous system lymphoma

(2017) Maxime Fontanilles et al.   Oncotarget

Targeting MYC Dependence by Metabolic Inhibitors in Cancer

(2017) Himalee S. Sabnis et al.   Genes

A Retrospective Analysis of Precision Medicine Outcomes in Patients With Advanced Cancer Reveals Improved Progression-Free Survival Without Increased Health Care Costs

(2017) Derrick S. Haslem et al.   Journal of Oncology Practice

Understanding type I and type II errors, statistical power and sample size

(2016) Anthony K. Akobeng   ACTA PAEDIATRICA

Sample size calculation while controlling false discovery rate for differential expression analysis with RNA-sequencing experiments

(2016) Ran Bi et al.   BMC BIOINFORMATICS

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Pharmacotherapies for the treatment of glioblastoma – current evidence and perspectives

(2016) Katharina Seystahl et al.   EXPERT OPINION ON PHARMACOTHERAPY

Mutant p53: a novel target for the treatment of patients with triple-negative breast cancer?

(2016) N.C. Synnott et al.   INTERNATIONAL JOURNAL OF CANCER

Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learned

(2016) Beth Linder et al.   OncoTargets and Therapy

Contemporary frameless intracranial biopsy techniques: Might variation in safety and efficacy be expected?

(2015) Iris S. C. Verploegh et al.   ACTA NEUROCHIRURGICA

Liquid biopsies in patients with diffuse glioma

(2015) Myron G. Best et al.   ACTA NEUROPATHOLOGICA

Detection ofK-rasgene mutation by liquid biopsy in patients with pancreatic cancer

(2015) Hideaki Kinugasa et al.   CANCER

Pharmacological reactivation of p53 as a strategy to treat cancer

(2015) J. Zawacka-Pankau et al.   JOURNAL OF INTERNAL MEDICINE

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

(2015) Yuxuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational analysis of primary central nervous system lymphoma

(2015) Aurélie Bruno et al.   Oncotarget

Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells

(2014) A. E. Vilgelm et al.   CANCER RESEARCH

Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer

(2014) P. J. Schuler et al.   CLINICAL CANCER RESEARCH

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma

(2014) Zhen Li et al.   MOLECULAR CANCER RESEARCH

Systems biology of primary CNS lymphoma: from genetic aberrations to modeling in mice

(2013) Martina Deckert et al.   ACTA NEUROPATHOLOGICA

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Diagnostic and prognostic value of circulating tumor-related DNA in cancer patients

(2013) Diego M Marzese et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

(2013) Garrett M Frampton et al.   NATURE BIOTECHNOLOGY

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients

(2012) L. Benesova et al.   ANALYTICAL BIOCHEMISTRY

Primary CNS lymphoma

(2012) Andrés J.M. Ferreri et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735

(2012) K. E. Hook et al.   MOLECULAR CANCER THERAPEUTICS

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

(2012) Luis A. Diaz Jr et al.   NATURE

MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells

(2011) K. A. Bridges et al.   CLINICAL CANCER RESEARCH

Prognostic Value of Free DNA Quantification in Serum and Cerebrospinal Fluid in Glioma Patients

(2011) Wei Shi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas

(2010) B.-L. Liu et al.   NEURO-ONCOLOGY