Identification of trans-eQTLs using mediation analysis with multiple mediators

Causal Mediation Analysis of Survival Outcome with Multiple Mediators

(2017) Yen-Tsung Huang et al.   EPIDEMIOLOGY

Identifyingcis-mediators fortrans-eQTLs across many human tissues using genomic mediation analysis

(2017) Fan Yang et al.   GENOME RESEARCH

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Simultaneous inference of phenotype-associated genes and relevant tissues from GWAS data via Bayesian integration of multiple tissue-specific gene networks

(2017) Mengmeng Wu et al.   Journal of Molecular Cell Biology

Estimating and testing high-dimensional mediation effects in epigenetic studies

(2016) Haixiang Zhang et al.   BIOINFORMATICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Hypothesis test of mediation effect in causal mediation model with high-dimensional continuous mediators

(2015) Yen-Tsung Huang et al.   BIOMETRICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

The Genetic and Mechanistic Basis for Variation in Gene Regulation

(2015) Athma A. Pai et al.   PLoS Genetics

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases

(2014) Yen-Tsung Huang et al.   Annals of Applied Statistics

More powerful genetic association testing via a new statistical framework for integrative genomics

(2014) Sihai D. Zhao et al.   BIOMETRICS

Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations

(2014) M. Weiser et al.   GENETICS

Integrative modeling of multi-platform genomic data under the framework of mediation analysis

(2014) Yen-Tsung Huang   STATISTICS IN MEDICINE

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

(2014) Sarah Kim et al.   Nature Communications

Mediation Analysis Demonstrates That Trans-eQTLs Are Often Explained by Cis-Mediation: A Genome-Wide Analysis among 1,800 South Asians

(2014) Brandon L. Pierce et al.   PLoS Genetics

Innate and adaptive immunity in inflammatory bowel disease

(2013) Alessandra Geremia et al.   AUTOIMMUNITY REVIEWS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

(2012) Steve Eyre et al.   NATURE GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Patterns of Cis Regulatory Variation in Diverse Human Populations

(2012) Barbara E. Stranger et al.   PLoS Genetics

From expression QTLs to personalized transcriptomics

(2011) Stephen B. Montgomery et al.   NATURE REVIEWS GENETICS

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Innate Immunity and Rheumatoid Arthritis

(2010) Angelica Gierut et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Identification, Inference and Sensitivity Analysis for Causal Mediation Effects

(2010) Kosuke Imai et al.   STATISTICAL SCIENCE

A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies

(2010) Oliver Stegle et al.   PLoS Computational Biology

Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

(2009) Mark S Silverberg et al.   NATURE GENETICS

TLRs and innate immunity

(2008) B. A. Beutler   BLOOD

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics