Fibrosis is not just fibrosis - basement membrane modelling and collagen metabolism differs between hepatitis B- and C-induced injury

Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution

(2016) Andrea Baiocchini et al.   PLoS One

HBV infection is associated with greater mortality in hospitalised patients compared to HCV infection or alcoholic liver disease

(2015) R. Rajbhandari et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

(2015) D. J. Leeming et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Combined antiretroviral therapy attenuates hepatic extracellular matrix remodeling in HIV patients assessed by novel protein fingerprint markers

(2014) Diana J. Leeming et al.   AIDS

Soluble CD163, a macrophage activation marker, is independently associated with fibrosis in patients with chronic viral hepatitis B and C

(2014) Konstantin Kazankov et al.   HEPATOLOGY

Hepatitis C virus in the new era: Perspectives in epidemiology, prevention, diagnostics and predictors of response to therapy

(2014) Filippo Ansaldi   WORLD JOURNAL OF GASTROENTEROLOGY

Different collagen types show distinct rates of increase from early to late stages of hepatitis C–related liver fibrosis

(2013) Wei Chen et al.   HUMAN PATHOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

(2012) Juliane S. Troeger et al.   GASTROENTEROLOGY

Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis

(2012) Diana J. Leeming et al.   HEPATOLOGY RESEARCH

Anti-fibrotic therapy: Lost in translation?

(2012) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

Cytokine Levels and Histopathology in Chronic Hepatitis B and Chronic Hepatitis C

(2012) Fusun Zeynep Akcam et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)

(2011) DJ. Leeming et al.   BIOMARKERS

MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay

(2011) Sanne Skovgård Veidal et al.   PLoS One

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

(2010) Michael Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen

(2010) N. Barascuk et al.   CLINICAL BIOCHEMISTRY

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the disease?

(2010) Morten Asser Karsdal et al.   CLINICAL BIOCHEMISTRY

Mapping structural landmarks, ligand binding sites, and missense mutations to the collagen IV heterotrimers predicts major functional domains, novel interactions, and variation in phenotypes in inherited diseases affecting basement membranes

(2010) J. Des Parkin et al.   HUMAN MUTATION

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways

(2009) Mohamed Hassan et al.   HEPATOLOGY

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY