A chemical engineering perspective of nanoparticle-based targeted drug delivery: A unit process approach

Physical Principles of Nanoparticle Cellular Endocytosis

(2015) Sulin Zhang et al.   ACS Nano

Dense nanoparticles exhibit enhanced vascular wall targeting over neutrally buoyant nanoparticles in human blood flow

(2015) Alex J. Thompson et al.   Acta Biomaterialia

Differential Impact of Plasma Proteins on the Adhesion Efficiency of Vascular-Targeted Carriers (VTCs) in Blood of Common Laboratory Animals

(2015) Katawut Namdee et al.   BIOCONJUGATE CHEMISTRY

A microfluidically perfused three dimensional human liver model

(2015) Knut Rennert et al.   BIOMATERIALS

Synthetic tumor networks for screening drug delivery systems

(2015) Balabhaskar Prabhakarpandian et al.   JOURNAL OF CONTROLLED RELEASE

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries

(2014) Aaron C. Anselmo et al.   ACS Nano

Super-Soft Hydrogel Particles with Tunable Elasticity in a Microfluidic Blood Capillary Model

(2014) Jiwei Cui et al.   ADVANCED MATERIALS

Organ-on-a-chip platforms for studying drug delivery systems

(2014) Nupura S. Bhise et al.   JOURNAL OF CONTROLLED RELEASE

Engineering and evaluating drug delivery particles in microfluidic devices

(2014) Mattias Björnmalm et al.   JOURNAL OF CONTROLLED RELEASE

A functional microengineered model of the human splenon-on-a-chip

(2014) L. G. Rigat-Brugarolas et al.   LAB ON A CHIP

Characterization of nanoparticle delivery in microcirculation using a microfluidic device

(2014) Antony Thomas et al.   MICROVASCULAR RESEARCH

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis

(2014) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theoretical and Computational Investigations of Nanoparticle-Biomembrane Interactions in Cellular Delivery

(2014) Hong-ming Ding et al.   Small

A Computational Model for Predicting Nanoparticle Accumulation in Tumor Vasculature

(2013) Hermann B. Frieboes et al.   PLoS One

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport

(2013) Alexandre Albanese et al.   Nature Communications

Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles

(2012) Erkki Ruoslahti   ADVANCED MATERIALS

Mimicking Adhesive Functionalities of Blood Platelets using Ligand-Decorated Liposomes

(2012) Madhumitha Ravikumar et al.   BIOCONJUGATE CHEMISTRY

Role of physicochemical properties of coating ligands in receptor-mediated endocytosis of nanoparticles

(2012) Hong-ming Ding et al.   BIOMATERIALS

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

SyM-BBB: a microfluidic blood brain barrier model

(2012) Balabhaskar Prabhakarpandian et al.   LAB ON A CHIP

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of red blood cells on nanoparticle targeted delivery in microcirculation

(2011) Jifu Tan et al.   Soft Matter

Physiologically Based Pharmacokinetic Modeling of Nanoparticles

(2010) Mingguang Li et al.   ACS Nano

Effects of particle size and ligand density on the kinetics of receptor-mediated endocytosis of nanoparticles

(2010) Hongyan Yuan et al.   APPLIED PHYSICS LETTERS

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

(2010) Jin-Wook Yoo et al.   CURRENT PHARMACEUTICAL DESIGN

The use of whole organ decellularization for the generation of a vascularized liver organoid

(2010) Pedro M. Baptista et al.   HEPATOLOGY

Fluid-shear-stress-induced translocation of aquaporin-2 and reorganization of actin cytoskeleton in renal tubular epithelial cells

(2010) Kyung-Jin Jang et al.   Integrative Biology

Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats

(2010) Hilliard L. Kutscher et al.   JOURNAL OF CONTROLLED RELEASE

Flow and adhesion of drug carriers in blood vessels depend on their shape: A study using model synthetic microvascular networks

(2010) Nishit Doshi et al.   JOURNAL OF CONTROLLED RELEASE

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments

(2009) Chi Zhang et al.   LAB ON A CHIP

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells

(2009) Kyung-Jin Jang et al.   LAB ON A CHIP

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY