Deep Consensus, a deep learning-based approach for particle pruning in cryo-electron microscopy

Cryo-EM structures of the human INO80 chromatin-remodeling complex

(2017) Ricardo J. Aramayo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly

(2017) Aida Razi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structures of the human INO80 chromatin-remodeling complex

(2017) Ricardo J. Aramayo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design

(2017) S. Rawson et al.   Acta Crystallographica Section D-Structural Biology

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

(2016) Alan Merk et al.   CELL

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

DeepPicker: A deep learning approach for fully automated particle picking in cryo-EM

(2016) Feng Wang et al.   JOURNAL OF STRUCTURAL BIOLOGY

The development of cryo-EM into a mainstream structural biology technique

(2016) Eva Nogales   NATURE METHODS

EMPIAR: a public archive for raw electron microscopy image data

(2016) Andrii Iudin et al.   NATURE METHODS

2.3 A resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

(2016) S. Banerjee et al.   SCIENCE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Semi-automated selection of cryo-EM particles in RELION-1.3

(2015) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Deep learning

(2015) Yann LeCun et al.   NATURE

2.2 A resolution cryo-EM structure of  -galactosidase in complex with a cell-permeant inhibitor

(2015) A. Bartesaghi et al.   SCIENCE

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

(2014) Wilson Wong et al.   eLife

A pattern matching approach to the automatic selection of particles from low-contrast electron micrographs

(2013) V. Abrishami et al.   BIOINFORMATICS

Automatic post-picking using MAPPOS improves particle image detection from cryo-EM micrographs

(2013) Ramin Norousi et al.   JOURNAL OF STRUCTURAL BIOLOGY

Particle quality assessment and sorting for automatic and semiautomatic particle-picking techniques

(2013) J. Vargas et al.   JOURNAL OF STRUCTURAL BIOLOGY

Xmipp 3.0: An improved software suite for image processing in electron microscopy

(2013) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Iterative Stable Alignment and Clustering of 2D Transmission Electron Microscope Images

(2012) Zhengfan Yang et al.   STRUCTURE

A clustering approach to multireference alignment of single-particle projections in electron microscopy

(2010) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

Automatic particle selection from electron micrographs using machine learning techniques

(2009) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY