Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway

Mechanisms involved in the possible nephroprotective effect of rutin and low dose γ irradiation against cisplatin-induced nephropathy in rats

(2017) Rasha R. Radwan et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Dexamethasone Attenuates LPS-induced Acute Lung Injury through Inhibition of NF-κB, COX-2, and Pro-inflammatory Mediators

(2016) Naif O. Al-Harbi et al.   IMMUNOLOGICAL INVESTIGATIONS

Rutin ameliorates kidney interstitial fibrosis in rats with obstructive nephropathy

(2016) Bin Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Rutin Prevents High Glucose-Induced Renal Glomerular Endothelial Hyperpermeability by Inhibiting the ROS/Rhoa/ROCK Signaling Pathway

(2016) Xiaoming Wang et al.   PLANTA MEDICA

Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats

(2016) Faisal Imam et al.   TOXICOLOGY MECHANISMS AND METHODS

Carfilzomib-induced cardiotoxicity mitigated by dexrazoxane through inhibition of hypertrophic gene expression and oxidative stress in rats

(2016) Naif O. Al-Harbi   TOXICOLOGY MECHANISMS AND METHODS

Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats

(2016) Faisal Imam et al.   TOXICOLOGY MECHANISMS AND METHODS

Carfilzomib-induced cardiotoxicity mitigated by dexrazoxane through inhibition of hypertrophic gene expression and oxidative stress in rats

(2016) Naif O. Al-Harbi   TOXICOLOGY MECHANISMS AND METHODS

Rutin Attenuates Carfilzomib-Induced Cardiotoxicity Through Inhibition of NF-κB, Hypertrophic Gene Expression and Oxidative Stress

(2015) Faisal Imam et al.   Cardiovascular Toxicology

Selenium and rutin alone or in combination do not have stronger protective effects than their separate effects against cadmium-induced renal damage

(2015) Sunny O. Abarikwu et al.   PHARMACEUTICAL BIOLOGY

Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity

(2015) Blanca Humanes et al.   Biomed Research International

Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: Possible mechanism of nephroprotection

(2014) Bidya Dhar Sahu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Renal thrombotic microangiopathy and podocytopathy associated with the use of carfilzomib in a patient with multiple myeloma

(2014) Liliane Hobeika et al.   BMC Nephrology

Olmesartan Attenuates Tacrolimus-Induced Biochemical and Ultrastructural Changes in Rat Kidney Tissue

(2014) Naif O. Al-Harbi et al.   Biomed Research International

Carfilzomib-related acute kidney injury may be prevented by N-acetyl-l-cysteine

(2014) Rimda Wanchoo et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma

(2013) M. Wang et al.   BLOOD

U.S. Food and Drug Administration Approval: Carfilzomib for the Treatment of Multiple Myeloma

(2013) T. M. Herndon et al.   CLINICAL CANCER RESEARCH

Integrated safety profile of single-agent carfilzomib: experience from 526 patients enrolled in 4 phase II clinical studies

(2013) D. Siegel et al.   HAEMATOLOGICA

Carfilzomib in multiple myeloma patients with renal impairment: pharmacokinetics and safety

(2013) A Z Badros et al.   LEUKEMIA

Design and rationale of FOCUS (PX-171-011): A randomized, open-label, phase 3 study of carfilzomib versus best supportive care regimen in patients with relapsed and refractory multiple myeloma (R/R MM)

(2012) Roman Hájek et al.   BMC CANCER

An open-label, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib

(2012) Ravi Vij et al.   BRITISH JOURNAL OF HAEMATOLOGY

Quercetin Ameliorates Cardiovascular, Hepatic, and Metabolic Changes in Diet-Induced Metabolic Syndrome in Rats

(2012) Sunil K. Panchal et al.   JOURNAL OF NUTRITION

Role of carfilzomib in the treatment of multiple myeloma

(2012) Rashid Z Khan et al.   Expert Review of Hematology

Rutin Attenuates Metabolic Changes, Nonalcoholic Steatohepatitis, and Cardiovascular Remodeling in High-Carbohydrate, High-Fat Diet-Fed Rats

(2011) Sunil K. Panchal et al.   JOURNAL OF NUTRITION

Evaluation for Antioxidant and Renoprotective Activity of Olmesartan Using Nephrectomy Rats

(2009) Daisuke Kadowaki et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve doxorubicin-induced cardiotoxicity and nephrotoxicity

(2009) Mohamed A. Ibrahim et al.   PHARMACOLOGICAL RESEARCH

Silymarin prevents adriamycin-induced cardiotoxicity and nephrotoxicity in rats

(2008) Nagla A. El-Shitany et al.   FOOD AND CHEMICAL TOXICOLOGY

Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity

(2008) O. Benavente-García et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY