Mini-HA Is Superior to Full Length Hemagglutinin Immunization in Inducing Stem-Specific Antibodies and Protection Against Group 1 Influenza Virus Challenges in Mice

Evaluation of Preexisting Anti-Hemagglutinin Stalk Antibody as a Correlate of Protection in a Healthy Volunteer Challenge with Influenza A/H1N1pdm Virus

(2018) Jae-Keun Park et al.   mBio

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

(2018) Lei Deng et al.   Nature Communications

Mini-hemagglutinin vaccination induces cross-reactive antibodies in pre-exposed NHP that protect mice against lethal influenza challenge

(2018) Joan E. M. van der Lubbe et al.   npj Vaccines

Divergent Requirement of Fc-Fcγ Receptor Interactions for In Vivo Protection against Influenza Viruses by Two Pan-H5 Hemagglutinin Antibodies

(2017) Shuangshuang Wang et al.   JOURNAL OF VIROLOGY

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

(2017) Silvie Van den Hoecke et al.   JOURNAL OF VIROLOGY

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model

(2017) Henning Jacobsen et al.   mBio

Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design

(2017) Sinthujan Jegaskanda et al.   Human Vaccines & Immunotherapeutics

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

(2017) Raffael Nachbagauer et al.   npj Vaccines

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

(2017) Troy C. Sutton et al.   npj Vaccines

HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids

(2016) Freek Cox et al.   Frontiers in Immunology

A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice

(2016) Raffael Nachbagauer et al.   npj Vaccines

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Advances in the development of influenza virus vaccines

(2015) Florian Krammer et al.   NATURE REVIEWS DRUG DISCOVERY

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

(2015) A. Impagliazzo et al.   SCIENCE

Immune history profoundly affects broadly protective B cell responses to influenza

(2015) Sarah F. Andrews et al.   Science Translational Medicine

FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities

(2015) Falk Nimmerjahn et al.   TRENDS IN IMMUNOLOGY

Protection against H5N1 by multiple immunizations with seasonal influenza vaccine in mice is correlated with H5 cross-reactive antibodies

(2015) Anna Roos et al.   VACCINE

Protection against H5N1 Influenza Virus Induced by Matrix-M Adjuvanted Seasonal Virosomal Vaccine in Mice Requires Both Antibodies and T Cells

(2015) Freek Cox et al.   PLoS One

Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

(2014) R. Nachbagauer et al.   JOURNAL OF VIROLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Transient Humoral Protection against H5N1 Challenge after Seasonal Influenza Vaccination of Humans

(2014) Ramon Roozendaal et al.   PLoS One

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

(2014) A. H. Ellebedy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly Neutralizing Antiviral Antibodies

(2013) Davide Corti et al.   Annual Review of Immunology

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

(2013) Andrea C Tricco et al.   BMC Medicine

Cross-Reactive Influenza-Specific Antibody-Dependent Cellular Cytotoxicity Antibodies in the Absence of Neutralizing Antibodies

(2013) S. Jegaskanda et al.   JOURNAL OF IMMUNOLOGY

Guiding the Immune Response against Influenza Virus Hemagglutinin toward the Conserved Stalk Domain by Hyperglycosylation of the Globular Head Domain

(2013) D. Eggink et al.   JOURNAL OF VIROLOGY

Antibody-Dependent Cellular Cytotoxicity Is Associated with Control of Pandemic H1N1 Influenza Virus Infection of Macaques

(2013) S. Jegaskanda et al.   JOURNAL OF VIROLOGY

Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Mechanisms of Hemagglutinin Targeted Influenza Virus Neutralization

(2013) Boerries Brandenburg et al.   PLoS One

Broader Neutralizing Antibodies against H5N1 Viruses Using Prime-Boost Immunization of Hyperglycosylated Hemagglutinin DNA and Virus-Like Particles

(2012) Shih-Chang Lin et al.   PLoS One

Highly Conserved Protective Epitopes on Influenza B Viruses

(2012) C. Dreyfus et al.   SCIENCE

Impacts on influenza A(H1N1)pdm09 infection from cross-protection of seasonal trivalent influenza vaccines and A(H1N1)pdm09 vaccines: Systematic review and meta-analyses

(2012) Jiehui Kevin Yin et al.   VACCINE

H3N2 Influenza Infection Elicits More Cross-Reactive and Less Clonally Expanded Anti-Hemagglutinin Antibodies Than Influenza Vaccination

(2011) M. Anthony Moody et al.   PLoS One

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

(2011) D. C. Ekiert et al.   SCIENCE

Acute effect of 1,25-dihydroxyvitamin D3, prednisone, and 1,25-dihydroxyvitamin D3 plus prednisone on serum osteocalcin in normal individuals

(2010) Henning K. Nielsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

(2010) C.-J. Wei et al.   SCIENCE

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE