A Novel Bacteriophage Lysin-Human Defensin Fusion Protein Is Effective in Treatment of Clostridioides difficile Infection in Mice

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

(2018) L Clifford McDonald et al.   CLINICAL INFECTIOUS DISEASES

Update on Antimicrobial Resistance in Clostridium difficile: Resistance Mechanisms and Antimicrobial Susceptibility Testing

(2017) Zhong Peng et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Clostridium difficile disease: Diagnosis, pathogenesis, and treatment update

(2017) Lena M. Napolitano et al.   SURGERY

Genome characterization of a novel binary toxin-positive strain of Clostridium difficile and comparison with the epidemic 027 and 078 strains

(2017) Zhong Peng et al.   Gut Pathogens

Antibiotic Resistance and Toxin Production of Clostridium difficile Isolates from the Hospitalized Patients in a Large Hospital in Florida

(2017) Zhong Peng et al.   Frontiers in Microbiology

The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa

(2017) Daniel B. Gilmer et al.   PLoS One

Reclassification of Clostridium difficile as Clostridioides difficile (Hall and O’Toole 1935) Prévot 1938

(2016) Paul A. Lawson et al.   ANAEROBE

Comparative genomic analysis of toxin-negative strains of Clostridium difficile from humans and animals with symptoms of gastrointestinal disease

(2016) Piklu Roy Chowdhury et al.   BMC MICROBIOLOGY

Burden of Six Healthcare-Associated Infections on European Population Health: Estimating Incidence-Based Disability-Adjusted Life Years through a Population Prevalence-Based Modelling Study

(2016) Alessandro Cassini et al.   PLOS MEDICINE

The non-toxigenic Clostridium difficile CD37 protects mice against infection with a BI/NAP1/027 type of C. difficile strain

(2015) Keshan Zhang et al.   ANAEROBE

Using a Novel Lysin To Help Control Clostridium difficile Infections

(2015) Qiong Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of a Novel Binary Toxin–Positive Strain of Clostridium difficile Associated With Severe Diarrhea That Was Not Ribotype 027 and 078 in China

(2015) Chunhui Li et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

New Role for Human α-Defensin 5 in the Fight against Hypervirulent Clostridium difficile Strains

(2014) Lucinda Furci et al.   INFECTION AND IMMUNITY

Clostridium difficile phages: still difficult?

(2014) Katherine R. Hargreaves et al.   Frontiers in Microbiology

European Society of Clinical Microbiology and Infectious Diseases: Update of the Treatment Guidance Document for Clostridium difficile Infection

(2013) S.B. Debast et al.   CLINICAL MICROBIOLOGY AND INFECTION

A Segment of 97 Amino Acids within the Translocation Domain of Clostridium difficile Toxin B Is Essential for Toxicity

(2013) Yongrong Zhang et al.   PLoS One

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Human α-Defensins Inhibit Clostridium difficile Toxin B

(2008) Torsten Giesemann et al.   GASTROENTEROLOGY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols