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Biochemistry & Molecular Biology
Armin Mooranian, Corina Mihaela Ionescu, Daniel Walker, Melissa Jones, Susbin Raj Wagle, Bozica Kovacevic, Jacqueline Chester, Thomas Foster, Edan Johnston, Jafri Kuthubutheen, Daniel Brown, Marcus D. Atlas, Momir Mikov, Hani Al-Salami
Summary: Recent studies have shown the potential applications of bile acid-Eudragit NM30D(R) capsules in drug encapsulation and viable-cell encapsulation. These capsules can improve cell viability, insulin levels, inflammatory profile, and bioenergetics, and the stability of the capsules is associated with cellular biological activities. Changes in ratios of bile acids to Eudragit NM30D(R) can alter the microenvironment of the capsules and subsequent cellular activities.
Article
Environmental Sciences
Zongfa Chen, Baosong Huang, Ziqi Yan, Yujie Hong, Mingming Zhao, Minxuan Jin, Anna Zheng, Zhongliang Wang
Summary: NHE and NKA are crucial regulators of ion transport in fish, and in this study 12 NHE genes and 12 NKA genes were identified in R. canadum. These genes were found to be distributed in gill, brain, and heart tissues, and showed specific expression patterns and responses to salinity changes.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Mai Abuowarda, Huda O. AbuBakr, Elshaimaa Ismael, Mohamed Shaalan, Mona A. Mohamed, Samira H. Aljuaydi
Summary: Leishmaniasis is a significant issue in Egypt, with dogs acting as the main reservoir host for this disease. Severe manifestations of cutaneous leishmaniasis were observed in humans, with phylogenetic analysis showing different strains of the parasite. Gene expression analysis in both blood and tissue samples confirmed the importance of certain genes in the disease's progression.
ZOONOSES AND PUBLIC HEALTH
(2021)
Article
Biology
Ranjan Rajeev, Sayanta Kundu, Teikur Majaw, Karma L. Bhutia
Summary: The present investigation aimed to study the performance of mutant lines obtained through gamma irradiations in terms of yield and yield attributing traits. It also focused on examining the expression of genes encoding antioxidant enzymes in control and gamma irradiated lines.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Fisheries
Nadia Gabr Ali, Tamer El-Sayed Ali, Ibrahim Mohamed Aboyadak, Mohamed Ahmed Elbakry
Summary: This study demonstrated the effectiveness of cefotaxime in treating Oreochromis niloticus brooders infected with virulent Pseudomonas aeruginosa, which showed high sensitivity to cefotaxime. The treated groups showed significant improvement in serum biochemical parameters and histopathological findings, with measured levels of cefotaxime in the fish's system and tissue residues.
Article
Biochemistry & Molecular Biology
Selena K. Tavener, Dennis E. Jewell, Kiran S. Panickar
Summary: Chronic low-grade inflammation is a significant factor in the progression of kidney disease, and activation of pro-inflammatory genes may contribute to renal inflammation and fibrosis. Blocking their activation could be important in ameliorating the initiation and/or progression of renal disease.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2022)
Article
Fisheries
Marwa M. Attia, Mamdouh Y. Elgendy, Mohamed Abdelsalam, Azza Hassan, Abdelbary Prince, Nagla M. K. Salaeh, Nehal A. Younis
Summary: This study identified heterophyid encysted metacercariae infecting gray mullets through morphological and molecular assays, showing a higher prevalence in wild-caught fish compared to farmed fish. Gene expression analysis indicated a significant increase in TNF-alpha and IL-10 in infected fish tissues, along with variable histopathological lesions in infected fish sections.
AQUACULTURE INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Muhammad Musa Khan, Ze-Yun Fan, Irfan Ali Sabir, Muhammad Hafeez, Sang Wen, Jian-Hui Wu, Bao-Li Qiu
Summary: This study investigated the effects of UV-C radiation on the physiology and gene expression of Plutella xylostella, a vegetable pest. The results showed that UV-C exposure suppressed the immunity of the pest and enhanced the virulence of entomopathogenic fungi. Additionally, UV irradiation was found to be an effective pest management tool that could reduce pesticide application and be economically beneficial and environmentally safe.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Mohammad Safarian, Manijeh Sabokdast Nodehi, Mohammad Reza Bihamta, Sajjad Sobhanverdi
Summary: This study aimed to investigate the stress responses of Mentha piperita under different lead concentrations. The results showed that the relative abundance of menthofuran synthase gene was downregulated, while the relative abundance of menthol reductase and pule gone reductase genes were upregulated under lead stress. Moreover, the menthol content also increased with intensifying lead stress. Moderate stress decreased chlorophyll and carotenoid content, and increased hydrogen peroxide content. Overall, these findings revealed the adaptation mechanisms of Mentha piperita under lead stress.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Cell Biology
Kunj Bihari Gupta, Anil K. Mantha, Monisha Dhiman
Summary: The study evaluated the inflammatory effects of wheat protein gliadin and the protective role of curcumin on human intestinal cell lines. The results demonstrated that gliadin exacerbates inflammation and cellular damage, while curcumin attenuates the inflammation and helps maintain cellular morphology.
Article
Chemistry, Medicinal
Nashwah G. M. Attallah, Engy Elekhnawy, Walaa A. Negm, Ismail A. Hussein, Fatma Alzahraa Mokhtar, Omnia Momtaz Al-Fakhrany
Summary: This study successfully synthesized silver nanoparticles using Gardenia thailandica leaf extract for the first time, and demonstrated their potential antibacterial activity against Staphylococcus aureus. The active constituents in the leaf extract were identified and their antioxidant activity was evaluated. The synthesized silver nanoparticles were characterized using various analytical techniques. Further experiments revealed that the silver nanoparticles induced morphological changes and altered gene expression in S. aureus bacteria, and showed wound healing and anti-inflammatory effects in vivo.
Article
Cardiac & Cardiovascular Systems
Adewale S. James, Regina N. Ugbaja, Emmanuel I. Ugwor, Funmilola C. Thomas, Adio J. Akamo, Dorcas I. Akinloye, Ofem E. Eteng, Shukurat K. Salami, Esther A. Emmanuel, Victory C. Ugbaja
Summary: This study evaluated the impact of lycopene (LYC) against palmitate (PA)-invoked cardiotoxicity. The results showed that LYC possesses anti-lipidemic, antioxidant, cytoprotective, and anti-inflammatory effects, and can reverse the cardiotoxicity caused by PA and improve tissue damage.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Fisheries
Kexin Zhang, Weiren Zhang, Ronghua Li, Junkai Lu, Qingwei Chen, Haojie Hu, Fei Yin, Changkao Mu, Weiwei Song, Chunlin Wang
Summary: This study reports the first infection of Mesanophrys sp. in mud crabs and investigates its impact on the crabs' survival, tissue distribution, and immune response. The infected group showed significantly lower survival rates and higher Mesanophrys sp. numbers in various tissues. Histopathological observation revealed tissue-specific pathogen infection. In addition, the infected group exhibited higher activity of antioxidant enzymes, indicating an immune defense reaction induced by Mesanophrys sp. infection. These findings are important for understanding the pathogenicity of Mesanophrys sp. and developing control measures for S. Paramamosain.
Article
Pharmacology & Pharmacy
Ahmed R. Hamed, Shaymaa M. M. Yahya, Heba K. Nabih
Summary: Hepatocellular carcinoma (HCC) is a major primary liver malignancy with limited early diagnosis and poor therapeutic outcomes. Melatonin, a promising antitumor agent, was found to inhibit the proliferation of doxorubicin-resistant HCC cells and downregulate drug resistance genes. The expression of apoptosis-related and anti-inflammatory genes was also elevated, indicating the potential of melatonin as an adjuvant therapy for human-resistant HCC.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2023)
Article
Toxicology
Shafiqur Rahman, Anil Kumar Sharma, Nittin Dev Singh, Shahid Prawez
Summary: This study found that T-2 toxin has significant suppressive effects on humoral and cell-mediated immune responses in rats after 12 weeks of exposure, leading to decreased levels of immunoglobulins and lymphocyte functions. The dose and duration of toxin exposure play a crucial role in this dose-dependent effect on the immune system.
HUMAN & EXPERIMENTAL TOXICOLOGY
(2021)
Article
Food Science & Technology
Perumal Venkatesh, Meleppat Balraj, Repally Ayyanna, Dasari Ankaiah, Venkatesan Arul
LWT-FOOD SCIENCE AND TECHNOLOGY
(2016)
Article
Biochemical Research Methods
Venkatesh Perumal, Ayyanna Repally, Ankaiah Dasari, Arul Venkatesan
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
(2016)
Article
Chemistry, Multidisciplinary
Palanichamy Esakkiraj, Balraj Meleppat, Avinash Kant Lakra, Repally Ayyanna, Venkatesan Arul
Article
Biochemistry & Molecular Biology
Palanichamy Esakkiraj, Christian Bharathi Antonyraj, Balraj Meleppat, Dasari Ankaiah, Repally Ayyanna, Syed Ibrahim Basheer Ahamed, Venkatesan Arul
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2017)
Article
Food Science & Technology
Dasari Ankaiah, Esakkiraj Palanichamy, Venkatesh Perumal, Repally Ayyanna, Arul Venkatesan
JOURNAL OF FUNCTIONAL FOODS
(2017)
Article
Biotechnology & Applied Microbiology
Ayyanna Repally, Venkatesh Perumal, Ankaiah Dasari, Esakkiraj Palanichamy, Arul Venkatesan
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2018)
Article
Biochemistry & Molecular Biology
Dasari Ankaiah, Esakkiraj Palanichamy, Christian Bharathi Antonyraj, Repally Ayyanna, Venkatesh Perumal, Syed Ibrahim Basheer Ahamed, Venkatesan Arul
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
