Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition

(2016) Cecilia Garlanda et al.   CURRENT OPINION IN IMMUNOLOGY

Fluid phase recognition molecules in neutrophil-dependent immune responses

(2016) Sébastien Jaillon et al.   SEMINARS IN IMMUNOLOGY

Update on molecular epidemiology of Shigella infection

(2015) Ila F.N. Lima et al.   CURRENT OPINION IN GASTROENTEROLOGY

Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice

(2015) Shannon J Heine et al.   IMMUNOLOGY AND CELL BIOLOGY

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

(2015) Andrea Doni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibacterial effect of porcine PTX3 against Streptococcus suis type 2 infection

(2015) Jueqiong Xu et al.   MICROBIAL PATHOGENESIS

Draft genomes of Shigella strains used by the STOPENTERICS consortium

(2015) Omar Rossi et al.   Gut Pathogens

Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

(2015) Barbara Bottazzi et al.   PLoS One

Shigella Vaccine Development: Prospective Animal Models and Current Status

(2014) Yeon-Jeong Kim et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection

(2014) Sébastien Jaillon et al.   IMMUNITY

B lymphocytes undergo TLR2-dependent apoptosis uponShigellainfection

(2014) Katharina Nothelfer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

(2014) P. C. Reading et al.   JOURNAL OF IMMUNOLOGY

Immunoregulatory effects on Caco-2 cells and mice of exopolysaccharides isolated from Lactobacillus acidophilus NCFM

(2014) Li Li et al.   Food & Function

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

(2013) S. Jaillon et al.   JOURNAL OF IMMUNOLOGY

Functional insights into theShigellatype III needle tip IpaD in secretion control and cell contact

(2013) Lionel Schiavolin et al.   MOLECULAR MICROBIOLOGY

Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation

(2013) I. Paciello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTX3 as a paradigm for the interaction of pentraxins with the Complement system

(2013) Antonio Inforzato et al.   SEMINARS IN IMMUNOLOGY

Response of CFTR-Deficient Mice to Long-Term chronic Pseudomonas aeruginosa Infection and PTX3 Therapy

(2012) Moira Paroni et al.   JOURNAL OF INFECTIOUS DISEASES

Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice

(2012) Bing Han et al.   LABORATORY INVESTIGATION

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

(2011) F. Moalli et al.   JOURNAL OF IMMUNOLOGY

Efficacy of PTX3 in a Rat Model of Invasive Aspergillosis

(2010) P. Lo Giudice et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of complement and Fc  receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

(2010) F. Moalli et al.   BLOOD

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality

(2010) Tommaso Mauri et al.   INTENSIVE CARE MEDICINE

Regulation of leukocyte recruitment by the long pentraxin PTX3

(2010) Livija Deban et al.   NATURE IMMUNOLOGY

An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

(2009) Barbara Bottazzi et al.   Annual Review of Immunology

Exogenous Pentraxin 3 Restores Antifungal Resistance and Restrains Inflammation in Murine Chronic Granulomatous Disease

(2009) C. D'Angelo et al.   JOURNAL OF IMMUNOLOGY

The IpaC Carboxyterminal Effector Domain Mediates Src-Dependent Actin Polymerization during Shigella Invasion of Epithelial Cells

(2009) Joëlle Mounier et al.   PLoS Pathogens

Muramylpeptide shedding modulates cell sensing of Shigella flexneri

(2008) Giulia Nigro et al.   CELLULAR MICROBIOLOGY

Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis

(2008) L. Steeghs et al.   INFECTION AND IMMUNITY

The versatility of Shigella effectors

(2007) Michinaga Ogawa et al.   NATURE REVIEWS MICROBIOLOGY

Phase 1 clinical trial of live attenuated Shigella dysenteriae type-1 ΔicsA Δent Δfep ΔstxA:HgR oral vaccine SC599 in healthy human adult volunteers

(2007) Christine Sadorge et al.   VACCINE