Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

Cellular and molecular biology ofNeisseria meningitidiscolonization and invasive disease

(2015) Darryl J. Hill et al.   CLINICAL SCIENCE

The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection

(2014) Sébastien Jaillon et al.   IMMUNITY

Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

(2014) P. C. Reading et al.   JOURNAL OF IMMUNOLOGY

Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

(2014) L. Deban et al.   JOURNAL OF IMMUNOLOGY

Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation

(2014) Cristina Cunha et al.   NEW ENGLAND JOURNAL OF MEDICINE

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

(2013) Alberto Mantovani et al.   Annals of the New York Academy of Sciences

Complement component C6 deficiency in a Spanish family: Implications for clinical and molecular diagnosis

(2013) M.R. Moya-Quiles et al.   GENE

Conservation of Meningococcal Antigens in the Genus Neisseria

(2013) A. Muzzi et al.   mBio

Meningococcal disease and the complement system

(2013) Lisa A Lewis et al.   Virulence

Response of CFTR-Deficient Mice to Long-Term chronic Pseudomonas aeruginosa Infection and PTX3 Therapy

(2012) Moira Paroni et al.   JOURNAL OF INFECTIOUS DISEASES

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

Mechanism of meningeal invasion byNeisseria meningitidis

(2012) Mathieu Coureuil et al.   Virulence

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

(2011) F. Moalli et al.   JOURNAL OF IMMUNOLOGY

M-Ficolin Interacts with the Long Pentraxin PTX3: A Novel Case of Cross-Talk between Soluble Pattern-Recognition Molecules

(2011) E. Gout et al.   JOURNAL OF IMMUNOLOGY

Human Pentraxin 3 Binds to the Complement Regulator C4b-Binding Protein

(2011) Anne Braunschweig et al.   PLoS One

Genome Wide Expression Profiling Reveals Suppression of Host Defence Responses during Colonisation by Neisseria meningitides but not N. lactamica

(2011) Hazel En En Wong et al.   PLoS One

Role of complement and Fc  receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

(2010) F. Moalli et al.   BLOOD

Characterization of fHbp, nhba (gna2132), nadA, porA, and Sequence Type in Group B Meningococcal Case Isolates Collected in England and Wales during January 2008 and Potential Coverage of an Investigational Group B Meningococcal Vaccine

(2010) J. Lucidarme et al.   Clinical and Vaccine Immunology

PTX3 genetic variations affect the risk of Pseudomonas aeruginosa airway colonization in cystic fibrosis patients

(2010) M Chiarini et al.   GENES AND IMMUNITY

The Angiogenic Inhibitor Long Pentraxin PTX3 Forms an Asymmetric Octamer with Two Binding Sites for FGF2

(2010) Antonio Inforzato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterocomplexes of Mannose-binding Lectin and the Pentraxins PTX3 or Serum Amyloid P Component Trigger Cross-activation of the Complement System

(2010) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serogroup B meningococcal vaccines—an unfinished story

(2010) Manish Sadarangani et al.   LANCET INFECTIOUS DISEASES

Regulation of leukocyte recruitment by the long pentraxin PTX3

(2010) Livija Deban et al.   NATURE IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

(2010) Davide Serruto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Influence of serogroup B meningococcal vaccine antigens on growth and survival of the meningococcus in vitro and in ex vivo and in vivo models of infection

(2010) Kate L. Seib et al.   VACCINE

The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement

(2010) Lisa A. Lewis et al.   PLoS Pathogens

The Long Pentraxin PTX3 Is Crucial for Tissue Inflammation after Intestinal Ischemia and Reperfusion in Mice

(2009) Danielle G. Souza et al.   AMERICAN JOURNAL OF PATHOLOGY

An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

(2009) Barbara Bottazzi et al.   Annual Review of Immunology

Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

(2009) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exogenous Pentraxin 3 Restores Antifungal Resistance and Restrains Inflammation in Murine Chronic Granulomatous Disease

(2009) C. D'Angelo et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development

(2009) Helena Lo et al.   LANCET INFECTIOUS DISEASES

Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis

(2009) Johan Holst et al.   VACCINE

Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease

(2009) Susanne Jacobsson et al.   VACCINE

Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis

(2009) David S. Stephens   VACCINE

The Macrophage Scavenger Receptor A Is Host-Protective in Experimental Meningococcal Septicaemia

(2009) Annette Plüddemann et al.   PLoS Pathogens

The Acute-Phase Reactant C-Reactive Protein Binds to Phosphorylcholine-Expressing Neisseria meningitidis and Increases Uptake by Human Phagocytes

(2008) R. Casey et al.   INFECTION AND IMMUNITY

Binding of Complement Factor H (fH) to Neisseria meningitidis Is Specific for Human fH and Inhibits Complement Activation by Rat and Rabbit Sera

(2008) D. M. Granoff et al.   INFECTION AND IMMUNITY

SR-A, MARCO and TLRs Differentially Recognise Selected Surface Proteins from Neisseria meningitidis: an Example of Fine Specificity in Microbial Ligand Recognition by Innate Immune Receptors

(2008) Annette Plüddemann et al.   Journal of Innate Immunity

Structural recognition and functional activation of FcγR by innate pentraxins

(2008) Jinghua Lu et al.   NATURE

Molecular and cellular signatures of human vaccine adjuvants

(2008) F. Mosca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PENTRAXIN 3 AND C-REACTIVE PROTEIN IN SEVERE MENINGOCOCCAL DISEASE

(2008) Tom Sprong et al.   SHOCK