Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental “Two-Hit” Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation

Impacts of stress on reproductive and social behaviors

(2018) A.M. Magariños et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The Effect of Leisure Activity Diversity and Exercise Time on the Prevention of Depression in the Middle-Aged and Elderly Residents of Taiwan

(2018) Hsiao-Yun Lee et al.   International Journal of Environmental Research and Public Health

Environmental Enrichment Reverses Tyrosine Kinase Inhibitor-Mediated Impairment Through BDNF-TrkB Pathway

(2017) Harkaitz Bengoetxea et al.   MOLECULAR NEUROBIOLOGY

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

(2017) Ariel Zeleznikow-Johnston et al.   NEUROPHARMACOLOGY

Neuroendocrine stress reactivity of male C57BL/6N mice following chronic oral corticosterone exposure during adulthood or adolescence

(2017) Ziasmin Shahanoor et al.   PSYCHONEUROENDOCRINOLOGY

Hippocampal BDNF in physiological conditions and social isolation

(2017) Ivan Zaletel et al.   REVIEWS IN THE NEUROSCIENCES

Interaction of reelin and stress on immobility in the forced swim test but not dopamine-mediated locomotor hyperactivity or prepulse inhibition disruption: Relevance to psychotic and mood disorders

(2017) Michael J. Notaras et al.   SCHIZOPHRENIA RESEARCH

Environmental Enrichment Improves Spatial Learning and Memory in Vascular Dementia Rats with Activation of Wnt/β-Catenin Signal Pathway

(2017) Xinhao Jin et al.   MEDICAL SCIENCE MONITOR

Schisandra chinensis produces the antidepressant-like effects in repeated corticosterone-induced mice via the BDNF/TrkB/CREB signaling pathway

(2016) Tingxu Yan et al.   PSYCHIATRY RESEARCH

Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment

(2016) Renzhong Xing et al.   Oncotarget

Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment

(2016) J Rogers et al.   Translational Psychiatry

Environmental enrichment in male CD-1 mice promotes aggressive behaviors and elevated corticosterone and brain norepinephrine activity in response to a mild stressor

(2016) Robyn J. McQuaid et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Gene–environment interaction of reelin and stress in cognitive behaviours in mice: Implications for schizophrenia

(2015) Anna Schroeder et al.   BEHAVIOURAL BRAIN RESEARCH

Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis

(2015) Alexander Garthe et al.   HIPPOCAMPUS

Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder

(2015) Veronica Reinhart et al.   NEUROBIOLOGY OF DISEASE

Effects of Long-Term Treatment with Estradiol and Estrogen Receptor Subtype Agonists on Serotonergic Function in Ovariectomized Rats

(2015) Saloua Benmansour et al.   NEUROENDOCRINOLOGY

Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5

(2015) Emma L Burrows et al.   NEUROPSYCHOPHARMACOLOGY

Inoculation stress hypothesis of environmental enrichment

(2015) Elizabeth J. Crofton et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

GABAergic mechanisms of hippocampal hyperactivity in schizophrenia

(2015) Stephan Heckers et al.   SCHIZOPHRENIA RESEARCH

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice

(2015) Stefano Garofalo et al.   Nature Communications

Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?

(2015) Xin Du et al.   Frontiers in Psychiatry

Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat's hippocampus

(2014) Wenyu Cao et al.   BEHAVIOURAL BRAIN RESEARCH

BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment

(2014) Tanja Novkovic et al.   HIPPOCAMPUS

Sex-specific disruptions in spatial memory and anhedonia in a “two hit” rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling

(2014) Rachel A. Hill et al.   HIPPOCAMPUS

Corticosterone treatment during adolescence induces down-regulation of reelin and NMDA receptor subunit GLUN2C expression only in male mice: implications for schizophrenia

(2014) Laetitia Buret et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Vascular hippocampal plasticity after aerobic exercise in older adults

(2014) A Maass et al.   MOLECULAR PSYCHIATRY

Hippocampal estradiol synthesis and its significance for hippocampal synaptic stability in male and female animals

(2014) R. Vierk et al.   NEUROSCIENCE

Structural Hippocampal Anomalies in a Schizophrenia Population Correlate with Navigation Performance on a Wayfinding Task

(2014) Andrée-Anne Ledoux et al.   Frontiers in Behavioral Neuroscience

COGNITIVE DEFICITS AND FUNCTIONAL OUTCOMES IN MAJOR DEPRESSIVE DISORDER: DETERMINANTS, SUBSTRATES, AND TREATMENT INTERVENTIONS

(2013) Roger S. McIntyre et al.   DEPRESSION AND ANXIETY

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Environmental enrichment induces neuroplastic changes in middle age female BalbC mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1/2

(2013) G. Ramírez-Rodríguez et al.   NEUROSCIENCE

A Loss-of-Function Screen for Phosphatases that Regulate Neurite Outgrowth Identifies PTPN12 as a Negative Regulator of TrkB Tyrosine Phosphorylation

(2013) Malene Ambjørn et al.   PLoS One

A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism

(2013) Naama Barnea-Goraly et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Social group memberships protect against future depression, alleviate depression symptoms and prevent depression relapse

(2013) Tegan Cruwys et al.   SOCIAL SCIENCE & MEDICINE

Music Therapy Modulates Fronto-Temporal Activity in Rest-EEG in Depressed Clients

(2012) Jörg Fachner et al.   BRAIN TOPOGRAPHY

Cortical circuit dysfunction and cognitive deficits in schizophrenia - implications for preemptive interventions

(2012) David A. Lewis   EUROPEAN JOURNAL OF NEUROSCIENCE

Modulatory Effects of Sex Steroid Hormones on Brain-Derived Neurotrophic Factor-Tyrosine Kinase B Expression during Adolescent Development in C57Bl/6 Mice

(2012) R. A. Hill et al.   JOURNAL OF NEUROENDOCRINOLOGY

Long-term behavioral and NMDA receptor effects of young-adult corticosterone treatment in BDNF heterozygous mice

(2012) Maren Klug et al.   NEUROBIOLOGY OF DISEASE

The impact of environmental enrichment on sex-specific neurochemical circuitries – Effects on brain-derived neurotrophic factor and the serotonergic system

(2012) S. Chourbaji et al.   NEUROSCIENCE

Brain-derived neurotrophic factor and glucocorticoids: Reciprocal influence on the central nervous system

(2012) T. Numakawa et al.   NEUROSCIENCE

The impact of environmental enrichment in laboratory rats—Behavioural and neurochemical aspects

(2011) Joy Simpson et al.   BEHAVIOURAL BRAIN RESEARCH

Individual music therapy for depression: randomised controlled trial

(2011) Jaakko Erkkilä et al.   BRITISH JOURNAL OF PSYCHIATRY

Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety

(2011) Quentin Rainer et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders

(2011) Mia Thompson Ray   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Laminin-β1 Impairs Spatial Learning through Inhibition of ERK/MAPK and SGK1 Signaling

(2011) Ying C Yang et al.   NEUROPSYCHOPHARMACOLOGY

The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

(2011) Bun-Hee Lee et al.   Psychiatry Investigation

Environmental enrichment and chronic restraint stress in ICR mice: Effects on prepulse inhibition of startle and Y-maze spatial recognition memory

(2010) Yanmei Chen et al.   BEHAVIOURAL BRAIN RESEARCH

Mutual Regulation of Src Family Kinases and the Neurotrophin Receptor TrkB

(2010) Yang Z. Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The environment and schizophrenia

(2010) Jim van Os et al.   NATURE

The environment and susceptibility to schizophrenia

(2010) Alan S. Brown   PROGRESS IN NEUROBIOLOGY

A Genetic Variant BDNF Polymorphism Alters Extinction Learning in Both Mouse and Human

(2010) F. Soliman et al.   SCIENCE

The Frequency of Cognitive Impairment in Patients With Anxiety, Depression, and Bipolar Disorder

(2009) C. Thomas Gualtieri et al.   JOURNAL OF CLINICAL PSYCHIATRY

The CRF system, stress, depression and anxiety—insights from human genetic studies

(2009) E B Binder et al.   MOLECULAR PSYCHIATRY

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

Regulation of the Hypothalamic-Pituitary-Adrenal Axis

(2009) Anastasios Papadimitriou et al.   NEUROIMMUNOMODULATION

Enriched environment influences hormonal status and hippocampal brain derived neurotrophic factor in a sex dependent manner

(2009) J. Bakos et al.   NEUROSCIENCE

The number of granule cells in rat hippocampus is reduced after chronic mild stress and re-established after chronic escitalopram treatment

(2007) Magdalena N. Jayatissa et al.   NEUROPHARMACOLOGY