Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson’s Disease

Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson’s disease

(2018) Vassilis E Papadopoulos et al.   HUMAN MOLECULAR GENETICS

Expression of the DJ-1 protein in the serum of Chinese patients with Parkinson’s disease

(2018) Chunna An et al.   NEUROSCIENCE LETTERS

Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy

(2018) Natascha Fussi et al.   Cell Death & Disease

Discovery, validation and optimization of cerebrospinal fluid biomarkers for use in Parkinson’s disease

(2017) Lucia Farotti et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome

(2017) Yi Yang et al.   PLoS One

Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff

(2017) Heiko Braak et al.   Journal of Parkinsons Disease

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease

(2016) Min Shi et al.   Alzheimers & Dementia

Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease

(2016) Edward J. Goetzl et al.   FASEB JOURNAL

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Advances in Biomarker Research in Parkinson’s Disease

(2015) Shyamal H. Mehta et al.   Current Neurology and Neuroscience Reports

A cell culture model for monitoring α-synuclein cell-to-cell transfer

(2015) Juan F. Reyes et al.   NEUROBIOLOGY OF DISEASE

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

(2015) Edward J. Goetzl et al.   NEUROLOGY

Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease

(2015) YaXing Gui et al.   Oncotarget

Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease

(2014) Min Shi et al.   ACTA NEUROPATHOLOGICA

The Parkinson's Disease-Related Protein DJ-1 Protects Dopaminergic Neurons in vivo and Cultured Cells from Alpha-Synuclein and 6-Hydroxydopamine Toxicity

(2014) Sara Batelli et al.   Neurodegenerative Diseases

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease

(2014) L Zondler et al.   Cell Death & Disease

Salivary DJ-1 could be an indicator of Parkinson's disease progression

(2014) Wen-Yan Kang et al.   Frontiers in Aging Neuroscience

Increased DJ-1 in Urine Exosome of Korean Males with Parkinson’s Disease

(2014) Dong Hwan Ho et al.   Biomed Research International

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

(2012) Shuang-Yong Sun et al.   BRAIN RESEARCH BULLETIN

EFNS/MDS-ES recommendations for the diagnosis of Parkinson's disease

(2012) A. Berardelli et al.   EUROPEAN JOURNAL OF NEUROLOGY

Alpha-synuclein: from secretion to dysfunction and death

(2012) O Marques et al.   Cell Death & Disease

DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease

(2012) Xiangmin Lin et al.   Scientific Reports

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease

(2011) Ivana Devic et al.   BRAIN

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

(2011) Lydia Alvarez-Erviti et al.   NEUROBIOLOGY OF DISEASE

Parkinsonism: Onset, progression, and mortality

(2011) M. Hoehn et al.   NEUROLOGY

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease

(2010) Min Shi et al.   NEUROSCIENCE LETTERS

Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood

(2008) Robin Barbour et al.   Neurodegenerative Diseases