DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease

DJ-1 Is a Copper Chaperone Acting on SOD1 Activation

(2014) Stefania Girotto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing the Dynamics of α-Synuclein Oligomers Using Hydrogen/Deuterium Exchange Monitored by Mass Spectrometry

(2013) Simon Mysling et al.   BIOCHEMISTRY

DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease

(2013) Muhammad U. Sajjad et al.   HUMAN MOLECULAR GENETICS

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

(2013) Sandra Tenreiro et al.   JOURNAL OF NEUROCHEMISTRY

PLK2 Modulates α-Synuclein Aggregation in Yeast and Mammalian Cells

(2013) Elisa Basso et al.   MOLECULAR NEUROBIOLOGY

Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization

(2013) Alireza Roostaee et al.   Molecular Neurodegeneration

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure

(2012) María Soledad Celej et al.   BIOCHEMICAL JOURNAL

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

(2012) Shuang-Yong Sun et al.   BRAIN RESEARCH BULLETIN

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

Parkinson’s disease-associated mutations in DJ-1 modulate its dimerization in living cells

(2012) Mariaelena Repici et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

(2012) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Accumulation of Toxic  -Synuclein Oligomer within Endoplasmic Reticulum Occurs in  -Synucleinopathy In Vivo

(2012) E. Colla et al.   JOURNAL OF NEUROSCIENCE

Alpha-synuclein: from secretion to dysfunction and death

(2012) O Marques et al.   Cell Death & Disease

Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease

(2011) Wenbo Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

(2011) Ken Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological roles of α-synuclein in neurological disorders

(2011) Kostas Vekrellis et al.   LANCET NEUROLOGY

Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy

(2011) Nahuai Badiola et al.   PLoS One

Interaction between -Synuclein and Other Proteins in Neurodegenerative Disorders

(2011) Kurt A. Jellinger   TheScientificWorldJOURNAL

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

(2010) I. Irrcher et al.   HUMAN MOLECULAR GENETICS

DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity

(2010) Satoshi Yamashita et al.   JOURNAL OF NEUROCHEMISTRY

L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments

(2010) Chenere P. Ramsey et al.   JOURNAL OF NEUROSCIENCE RESEARCH

DJ-1, PINK1, and their effects on mitochondrial pathways

(2010) Mark R. Cookson   MOVEMENT DISORDERS

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway

(2010) H. Aleyasin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zooming into protein oligomerization in neurodegeneration using BiFC

(2010) Susana A. Gonçalves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Yeast as a model for studying human neurodegenerative disorders

(2008) Leonor Miller-Fleming et al.   Biotechnology Journal

α-synuclein and Parkinson’s disease: a proteomic view

(2008) Mauro Fasano et al.   Expert Review of Proteomics

Formation of Toxic Oligomeric α-Synuclein Species in Living Cells

(2008) Tiago Fleming Outeiro et al.   PLoS One

Structural effects of Parkinson's disease linked DJ-1 mutations

(2008) Gaetano Malgieri et al.   PROTEIN SCIENCE